Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf [V600E]' and Ligand = 'BDBM103663'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human))	BDBM103663 (US8563553, 88) Show SMILES CCCNc1nccc(n1)-c1nc([nH]c1-c1cc(F)cc(NS(=O)(=O)CCC)c1Cl)C1CC1 Show InChI InChI=1S/C22H26ClFN6O2S/c1-3-8-25-22-26-9-7-16(27-22)20-19(28-21(29-20)13-5-6-13)15-11-14(24)12-17(18(15)23)30-33(31,32)10-4-2/h7,9,11-13,30H,3-6,8,10H2,1-2H3,(H,28,29)(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.390	n/a	n/a	n/a	n/a	7.5	n/a
Novartis AG; IRM LLC US Patent					Assay Description Raf/Mek amplified luminescence proximity homogeneous assay.				US Patent US8563553 (2013) BindingDB Entry DOI: 10.7270/Q2ZP44R7
					More data for this Ligand-Target Pair