Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Sgk1' and Ligand = 'BDBM268921'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM268921 (US9718825, Example 346) Show SMILES CC(C)N1CCC(CC1)Oc1nc(nc2[nH]nc(C)c12)-c1ccc(NS(=O)(=O)c2cc(Cl)ccc2F)cc1 Show InChI InChI=1S/C26H28ClFN6O3S/c1-15(2)34-12-10-20(11-13-34)37-26-23-16(3)31-32-25(23)29-24(30-26)17-4-7-19(8-5-17)33-38(35,36)22-14-18(27)6-9-21(22)28/h4-9,14-15,20,33H,10-13H2,1-3H3,(H,29,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01601 BindingDB Entry DOI: 10.7270/Q2P55SCW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM268921 (US9718825, Example 346) Show SMILES CC(C)N1CCC(CC1)Oc1nc(nc2[nH]nc(C)c12)-c1ccc(NS(=O)(=O)c2cc(Cl)ccc2F)cc1 Show InChI InChI=1S/C26H28ClFN6O3S/c1-15(2)34-12-10-20(11-13-34)37-26-23-16(3)31-32-25(23)29-24(30-26)17-4-7-19(8-5-17)33-38(35,36)22-14-18(27)6-9-21(22)28/h4-9,14-15,20,33H,10-13H2,1-3H3,(H,29,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01601 BindingDB Entry DOI: 10.7270/Q2P55SCW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM268921 (US9718825, Example 346) Show SMILES CC(C)N1CCC(CC1)Oc1nc(nc2[nH]nc(C)c12)-c1ccc(NS(=O)(=O)c2cc(Cl)ccc2F)cc1 Show InChI InChI=1S/C26H28ClFN6O3S/c1-15(2)34-12-10-20(11-13-34)37-26-23-16(3)31-32-25(23)29-24(30-26)17-4-7-19(8-5-17)33-38(35,36)22-14-18(27)6-9-21(22)28/h4-9,14-15,20,33H,10-13H2,1-3H3,(H,29,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	7.4	n/a
SANOFI US Patent					Assay Description The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...				US Patent US9718825 (2017) BindingDB Entry DOI: 10.7270/Q2VM4F82
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Mus musculus (Mouse))	BDBM268921 (US9718825, Example 346) Show SMILES CC(C)N1CCC(CC1)Oc1nc(nc2[nH]nc(C)c12)-c1ccc(NS(=O)(=O)c2cc(Cl)ccc2F)cc1 Show InChI InChI=1S/C26H28ClFN6O3S/c1-15(2)34-12-10-20(11-13-34)37-26-23-16(3)31-32-25(23)29-24(30-26)17-4-7-19(8-5-17)33-38(35,36)22-14-18(27)6-9-21(22)28/h4-9,14-15,20,33H,10-13H2,1-3H3,(H,29,30,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	171	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mouse SGK1 in presence 500 uM presence of ATP				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01601 BindingDB Entry DOI: 10.7270/Q2P55SCW
					More data for this Ligand-Target Pair