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Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM26623'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-2


(Homo sapiens (Human))
BDBM26623
PNG
((5Z)-5-[(4-methylphenyl)methylidene]-1,3-thiazolid...)
Show SMILES Cc1ccc(C=C2SC(O)=NC2=O)cc1 |w:5.4,c:9|
Show InChI InChI=1S/C11H9NO2S/c1-7-2-4-8(5-3-7)6-9-10(13)12-11(14)15-9/h2-6H,1H3,(H,12,13,14)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 4.40E+3n/an/an/an/an/an/a



Medical University of South Carolina



Assay Description
The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...


J Med Chem 52: 74-86 (2009)


Article DOI: 10.1021/jm800937p
BindingDB Entry DOI: 10.7270/Q2S180SF
More data for this
Ligand-Target Pair