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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine protease 1' and Ligand = 'BDBM50046373'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine protease 1


(Homo sapiens (Human))		BDBM50046373
PNG
(CHEMBL108670 | {1-(3,4-Dichloro-phenyl)-2-[2-(1-fo...)
Show SMILES CC(C)(C)OC(=O)NC(C(=O)N1CCC[C@H]1C(=O)NC(CCCNC(N)=N)C=O)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C24H34Cl2N6O5/c1-24(2,3)37-23(36)31-19(14-8-9-16(25)17(26)12-14)21(35)32-11-5-7-18(32)20(34)30-15(13-33)6-4-10-29-22(27)28/h8-9,12-13,15,18-19H,4-7,10-11H2,1-3H3,(H,30,34)(H,31,36)(H4,27,28,29)/t15?,18-,19?/m0/s1
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n/an/a 15n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against trypsin

J Med Chem 36: 314-9 (1993)


BindingDB Entry DOI: 10.7270/Q2930S8J
More data for this
Ligand-Target Pair