Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM22186'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22186 (4-(4-{2-[bis(4-fluorophenyl)methoxy]ethyl}piperazi...) Show SMILES CC(O)(CCN1CCN(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1)c1ccccc1 Show InChI InChI=1S/C29H34F2N2O2/c1-29(34,25-5-3-2-4-6-25)15-16-32-17-19-33(20-18-32)21-22-35-28(23-7-11-26(30)12-8-23)24-9-13-27(31)14-10-24/h2-14,28,34H,15-22H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	4	-44.6	n/a	n/a	n/a	n/a	n/a	7.4	4
National Taiwan University					Assay Description The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...				J Med Chem 51: 2795-806 (2008) Article DOI: 10.1021/jm701270n BindingDB Entry DOI: 10.7270/Q2B27SK6
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