BindingDB PrimarySearch

Found 20 hits Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM86701'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse--Intramural Research Program Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 from dopamine transporter of rat brain membrane				Bioorg Med Chem Lett 14: 3295-8 (2004) Article DOI: 10.1016/j.bmcl.2004.03.075 BindingDB Entry DOI: 10.7270/Q2F76D43
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse--Intramural Research Program Curated by ChEMBL					Assay Description Displacement of [3H]WIN-from DAT in rat brain membrane				Bioorg Med Chem Lett 15: 5419-23 (2005) Article DOI: 10.1016/j.bmcl.2005.08.111 BindingDB Entry DOI: 10.7270/Q2KP82XR
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat brain				J Med Chem 49: 6391-9 (2006) Article DOI: 10.1021/jm060762q BindingDB Entry DOI: 10.7270/Q2WD41D4
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by PDSP K_i Database									J Pharmacol Exp Ther 314: 575-83 (2005) Article DOI: 10.1124/jpet.105.085829 BindingDB Entry DOI: 10.7270/Q27M06H6
Duquesne University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Ability to displace [3H]-WIN- 35 radioligand for the dopamine transporter 428 DAT in rat brain				Bioorg Med Chem Lett 12: 1249-52 (2002) BindingDB Entry DOI: 10.7270/Q2Z037GM
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	11.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 from the dopamine transporter in rat caudate putamen				J Med Chem 43: 1085-93 (2000) BindingDB Entry DOI: 10.7270/Q2M61KZ7
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse--Intramural Research Program Curated by ChEMBL					Assay Description Binding affinity at dopamine transporter in rat brain by [3H]WIN-35428 displacement.				J Med Chem 47: 3388-98 (2004) Article DOI: 10.1021/jm030646c BindingDB Entry DOI: 10.7270/Q2WS8TZ4
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by ChEMBL					Assay Description In vitro dopamine transporter binding affinity using [3H]WIN-35428 as radioligand was determined				J Med Chem 46: 2908-16 (2003) Article DOI: 10.1021/jm0300375 BindingDB Entry DOI: 10.7270/Q2BG2PQ0
National Institute on Drug Abuse Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Affinity for rat dopamine transporter using [3H]WIN-35428 displacement.				J Med Chem 38: 3933-40 (1995) BindingDB Entry DOI: 10.7270/Q20V8DF2
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse - Intramural Research Program Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 binding to the dopamine transporter in rat caudate putamen tissue.				J Med Chem 42: 3502-9 (1999) Article DOI: 10.1021/jm980701v BindingDB Entry DOI: 10.7270/Q2VD705D
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]WIN-35428 binding in rat caudate-putamen				J Med Chem 37: 2258-61 (1994) BindingDB Entry DOI: 10.7270/Q2FJ2HFZ
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Binding affinity to dopamine transporter (DAT) using [3H]WIN-35428 as a radioligand				J Med Chem 43: 4151-9 (2000) Article DOI: 10.1021/jm990472s BindingDB Entry DOI: 10.7270/Q2PK0JWZ
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by ChEMBL					Assay Description Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.				J Med Chem 40: 4329-39 (1998) Article DOI: 10.1021/jm970525a BindingDB Entry DOI: 10.7270/Q2CV4GV5
National Institute on Drug Abuse Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Ability of compound to inhibit dopamine uptake of receptor was determined				Bioorg Med Chem Lett 15: 2149-57 (2005) Article DOI: 10.1016/j.bmcl.2005.02.012 BindingDB Entry DOI: 10.7270/Q2RR20G2
Pomona College Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by PDSP K_i Database									J Pharmacol Exp Ther 314: 575-83 (2005) Article DOI: 10.1124/jpet.105.085829 BindingDB Entry DOI: 10.7270/Q27M06H6
Duquesne University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by ChEMBL					Assay Description In vitro inhibition of dopamine uptake in rat tissue, was determined using [3H]-DAU as radioligand				J Med Chem 40: 4329-39 (1998) Article DOI: 10.1021/jm970525a BindingDB Entry DOI: 10.7270/Q2CV4GV5
National Institute on Drug Abuse Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13.8	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by ChEMBL					Assay Description In vitro potency for inhibiting [3H]- dopamine uptake was determined				J Med Chem 46: 2908-16 (2003) Article DOI: 10.1021/jm0300375 BindingDB Entry DOI: 10.7270/Q2BG2PQ0
National Institute on Drug Abuse Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Organix Inc Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to the dopamine transporter in the cynomolgus (macaca fascicularis) monkey caudate-putamen.				J Med Chem 39: 371-9 (1996) Article DOI: 10.1021/jm950463t BindingDB Entry DOI: 10.7270/Q2Q240XF
Organix Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine uptake in rat caudate putamen.				J Med Chem 38: 3933-40 (1995) BindingDB Entry DOI: 10.7270/Q20V8DF2
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86701 (3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse - Intramural Research Program Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine uptake in rat caudate putamen tissue.				J Med Chem 42: 3502-9 (1999) Article DOI: 10.1021/jm980701v BindingDB Entry DOI: 10.7270/Q2VD705D
					More data for this Ligand-Target Pair