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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sterol O-acyltransferase 1' and Ligand = 'BDBM50002953'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50002953
PNG
(8-(5,6-Diphenyl-pyridazin-3-ylsulfanyl)-octanoic a...)
Show SMILES OC(=O)CCCCCCCSc1cc(-c2ccccc2)c(nn1)-c1ccccc1
Show InChI InChI=1S/C24H26N2O2S/c27-23(28)16-10-2-1-3-11-17-29-22-18-21(19-12-6-4-7-13-19)24(26-25-22)20-14-8-5-9-15-20/h4-9,12-15,18H,1-3,10-11,16-17H2,(H,27,28)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>3.00E+5n/an/an/an/an/an/a



Università di Firenze

Curated by ChEMBL


Assay Description
In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes

J Med Chem 44: 4292-5 (2001)


BindingDB Entry DOI: 10.7270/Q2W37VMS
More data for this
Ligand-Target Pair