Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1 [T204D]' and Ligand = 'BDBM283047'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 [T204D] (Homo sapiens (Human))	BDBM283047 (6-(1-(2,2-difluoroethyl)-4-(2-hydroxyphenyl)-1H- i...) Show SMILES Oc1ccccc1-c1ncn(CC(F)F)c1-c1ccc2ncc(C#N)n2n1 Show InChI InChI=1S/C18H12F2N6O/c19-15(20)9-25-10-23-17(12-3-1-2-4-14(12)27)18(25)13-5-6-16-22-8-11(7-21)26(16)24-13/h1-6,8,10,15,27H,9H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin at Madison					Assay Description Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...				J Med Chem 51: 7243-52 (2008) BindingDB Entry DOI: 10.7270/Q2B85BFB
					More data for this Ligand-Target Pair