Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50233823 (CHEMBL4097807) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of telomerase activity in human MDA-MB-435 cell lysate measured after 24 hrs by TRAP assay | Eur J Med Chem 125: 117-129 (2017) Article DOI: 10.1016/j.ejmech.2016.09.028 BindingDB Entry DOI: 10.7270/Q2NS0X5V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50233823 (CHEMBL4097807) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of telomerase activity in human U2OS cell lysate measured after 24 hrs by TRAP assay | Eur J Med Chem 125: 117-129 (2017) Article DOI: 10.1016/j.ejmech.2016.09.028 BindingDB Entry DOI: 10.7270/Q2NS0X5V | |||||||||||
More data for this Ligand-Target Pair |