Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Ligand = 'BDBM50253785'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50253785 (9,10-Dioxo-9,10-dihydro-anthracene-2,7-dicarboxyli...) Show SMILES NCCCC[C@H](N)C(=O)NCCNC(=O)c1ccc2C(=O)c3ccc(cc3C(=O)c2c1)C(=O)NCCNC(=O)[C@@H](N)CCCCN |r| Show InChI InChI=1S/C32H44N8O6/c33-11-3-1-5-25(35)31(45)39-15-13-37-29(43)19-7-9-21-23(17-19)28(42)24-18-20(8-10-22(24)27(21)41)30(44)38-14-16-40-32(46)26(36)6-2-4-12-34/h7-10,17-18,25-26H,1-6,11-16,33-36H2,(H,37,43)(H,38,44)(H,39,45)(H,40,46)/t25-,26-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
University of Padova Curated by ChEMBL					Assay Description Inhibition of telomerase in human JR8 cells by TRAP assay				J Med Chem 51: 5566-74 (2008) Article DOI: 10.1021/jm800160v BindingDB Entry DOI: 10.7270/Q2R78F1Q
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