Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thrombopoietin receptor' and Ligand = 'BDBM50179478'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50179478 (5-((2-(6-(3,4-dimethylphenyl)pyridin-2-yl)-1H-benz...) Show SMILES Cc1ccc(cc1C)-c1cccc(n1)-c1nc2ccc(C=C3SC(S)=NC3=O)cc2[nH]1 |w:20.21,c:26| Show InChI InChI=1S/C24H18N4OS2/c1-13-6-8-16(10-14(13)2)17-4-3-5-19(25-17)22-26-18-9-7-15(11-20(18)27-22)12-21-23(29)28-24(30)31-21/h3-12H,1-2H3,(H,26,27)(H,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPOR				Bioorg Med Chem Lett 16: 1212-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.096 BindingDB Entry DOI: 10.7270/Q2V124BM
					More data for this Ligand-Target Pair