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Found 1 hit Enz. Inhib. hit(s) with Target = 'Thromboxane-A synthase' and Ligand = 'BDBM50024914'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thromboxane-A synthase


(Rattus norvegicus)		BDBM50024914
PNG
(6-Chloro-3-(6-imidazol-1-yl-hexyl)-1H-quinazoline-...)
Show SMILES Clc1ccc2[nH]c(=O)n(CCCCCCn3ccnc3)c(=O)c2c1
Show InChI InChI=1S/C17H19ClN4O2/c18-13-5-6-15-14(11-13)16(23)22(17(24)20-15)9-4-2-1-3-8-21-10-7-19-12-21/h5-7,10-12H,1-4,8-9H2,(H,20,24)
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Similars
PubMed
n/an/a 4n/an/an/an/an/an/a



Medical Research Division of American Cyanamid Company

Curated by ChEMBL


Assay Description
Tested for inhibition of thromboxane synthetase from spontaneously hypertensive rats

J Med Chem 30: 2277-83 (1988)


BindingDB Entry DOI: 10.7270/Q23T9HT6
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Ligand-Target Pair