BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thromboxane-A synthase' and Ligand = 'BDBM50034746'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thromboxane-A synthase


(Homo sapiens (Human))		BDBM50034746
PNG
((E)-7-[4-(6-{3-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2...)
Show SMILES OC(=O)CCCC\C=C(/c1ccc(OCCCCCCOc2cccc(c2)[C@H]2OC[C@@H](C\C=C/CCC(O)=O)[C@H](O2)c2ccccc2O)cc1)c1cccnc1
Show InChI InChI=1S/C46H53NO9/c48-42-21-10-9-20-41(42)45-37(15-5-3-7-22-43(49)50)33-55-46(56-45)35-16-13-18-39(31-35)54-30-12-2-1-11-29-53-38-26-24-34(25-27-38)40(36-17-14-28-47-32-36)19-6-4-8-23-44(51)52/h3,5,9-10,13-14,16-21,24-28,31-32,37,45-46,48H,1-2,4,6-8,11-12,15,22-23,29-30,33H2,(H,49,50)(H,51,52)/b5-3-,40-19+/t37-,45+,46+/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 70n/an/an/an/an/an/a



ZENECA Pharmaceuticals

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human microsomal thromboxane synthase.

J Med Chem 38: 1608-28 (1995)


BindingDB Entry DOI: 10.7270/Q2319TWW
More data for this
Ligand-Target Pair