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Found 1 hit Enz. Inhib. hit(s) with Target = 'Thromboxane-A synthase' and Ligand = 'BDBM50037045'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thromboxane-A synthase


(Rattus norvegicus)		BDBM50037045
PNG
(5-Methoxy-7-methyl-2-methylamino-4-pyridin-3-ylmet...)
Show SMILES CNc1nc2c(Cc3cccnc3)c(OC)c(O)c(C)c2s1
Show InChI InChI=1S/C16H17N3O2S/c1-9-13(20)14(21-3)11(7-10-5-4-6-18-8-10)12-15(9)22-16(17-2)19-12/h4-6,8,20H,7H2,1-3H3,(H,17,19)
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PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Eisai Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of rat

J Med Chem 37: 3062-70 (1994)


BindingDB Entry DOI: 10.7270/Q2WM1F2J
More data for this
Ligand-Target Pair