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Found 1 hit Enz. Inhib. hit(s) with Target = 'Thromboxane-A synthase' and Ligand = 'BDBM50037763'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thromboxane-A synthase


(Rattus norvegicus)		BDBM50037763
PNG
(6-[2-Imidazol-1-yl-1,3-diphenyl-prop-(E)-ylideneam...)
Show SMILES OC(=O)CCCCCO\N=C(\C(Cc1ccccc1)n1ccnc1)c1ccccc1
Show InChI InChI=1S/C24H27N3O3/c28-23(29)14-8-3-9-17-30-26-24(21-12-6-2-7-13-21)22(27-16-15-25-19-27)18-20-10-4-1-5-11-20/h1-2,4-7,10-13,15-16,19,22H,3,8-9,14,17-18H2,(H,28,29)/b26-24+
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PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Pharmacia-Farmitalia Carlo Erba

Curated by ChEMBL


Assay Description
In vitro inhibition of thromboxane-A2 synthase in rat whole blood during clotting at 37 degrees centigrade

J Med Chem 37: 3588-604 (1994)


BindingDB Entry DOI: 10.7270/Q2C24VFD
More data for this
Ligand-Target Pair