BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Thromboxane-A synthase' and Ligand = 'BDBM50110446'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thromboxane-A synthase


(Homo sapiens (Human))		BDBM50110446
PNG
(5-{[1-{3-[6-(2-chlorophenyl)-1,4-dimethyl-7,8,9,10...)
Show SMILES CC1N=C(c2c3CCN(Cc4cccc(c4)C(=N/OCCCCC(O)=O)\c4cccnc4)Cc3sc2-n2c(C)nnc12)c1ccccc1Cl |c:2|
Show InChI InChI=1S/C37H36ClN7O3S/c1-23-36-42-41-24(2)45(36)37-33(35(40-23)28-12-3-4-13-30(28)38)29-15-17-44(22-31(29)49-37)21-25-9-7-10-26(19-25)34(27-11-8-16-39-20-27)43-48-18-6-5-14-32(46)47/h3-4,7-13,16,19-20,23H,5-6,14-15,17-18,21-22H2,1-2H3,(H,46,47)/b43-34+
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 24n/an/an/an/an/an/a



Nikken Chemicals Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of thromboxane synthase (TXA2) in human platelet microsomes [reduced formation of TXB2 from prostaglandin H2(PGH2)]

Bioorg Med Chem Lett 12: 771-4 (2002)


BindingDB Entry DOI: 10.7270/Q23X85ZH
More data for this
Ligand-Target Pair