Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM20538'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM20538 (2-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}ox...) Show SMILES FC(F)(F)c1ccc(cc1)-c1cc(Oc2ccc3ccccc3n2)ncn1 Show InChI InChI=1S/C20H12F3N3O/c21-20(22,23)15-8-5-14(6-9-15)17-11-19(25-12-24-17)27-18-10-7-13-3-1-2-4-16(13)26-18/h1-12H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	7.4	22
Amgen					Assay Description TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...				J Med Chem 50: 3515-27 (2007) Article DOI: 10.1021/jm070190p BindingDB Entry DOI: 10.7270/Q2RN364D
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM20538 (2-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}ox...) Show SMILES FC(F)(F)c1ccc(cc1)-c1cc(Oc2ccc3ccccc3n2)ncn1 Show InChI InChI=1S/C20H12F3N3O/c21-20(22,23)15-8-5-14(6-9-15)17-11-19(25-12-24-17)27-18-10-7-13-3-1-2-4-16(13)26-18/h1-12H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...				J Med Chem 50: 3515-27 (2007) Article DOI: 10.1021/jm070190p BindingDB Entry DOI: 10.7270/Q2RN364D
					More data for this Ligand-Target Pair