Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM351765'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM351765 (US9796716, Compound 11) Show SMILES COc1ccc(COc2cccc(Oc3ccc(cc3)-c3nn(C4CCCC4)c4ncnc(N)c34)c2)cc1 Show InChI InChI=1S/C30H29N5O3/c1-36-23-13-9-20(10-14-23)18-37-25-7-4-8-26(17-25)38-24-15-11-21(12-16-24)28-27-29(31)32-19-33-30(27)35(34-28)22-5-2-3-6-22/h4,7-17,19,22H,2-3,5-6,18H2,1H3,(H2,31,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PHARMASCIENCE, INC. US Patent					Assay Description Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length Bruton Aga...				US Patent US9796716 (2017) BindingDB Entry DOI: 10.7270/Q2MW2K8J
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