Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2 [808-1132]' and Ligand = 'BDBM127762'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 [808-1132] (Homo sapiens (Human))	BDBM127762 (US10758542, Example 135 | US8791123, 135 | US97824...) Show SMILES O[C@H]1CCC[C@H]1NC(=O)c1cnn2ccc(nc12)N1CCC[C@@H]1c1cncc(F)c1 |r| Show InChI InChI=1S/C21H23FN6O2/c22-14-9-13(10-23-11-14)17-4-2-7-27(17)19-6-8-28-20(26-19)15(12-24-28)21(30)25-16-3-1-5-18(16)29/h6,8-12,16-18,29H,1-5,7H2,(H,25,30)/t16-,17-,18+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc. US Patent					Assay Description Jak2: Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mix...				US Patent US10758542 (2020) BindingDB Entry DOI: 10.7270/Q2RB77PD
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [808-1132] (Homo sapiens (Human))	BDBM127762 (US10758542, Example 135 | US8791123, 135 | US97824...) Show SMILES O[C@H]1CCC[C@H]1NC(=O)c1cnn2ccc(nc12)N1CCC[C@@H]1c1cncc(F)c1 |r| Show InChI InChI=1S/C21H23FN6O2/c22-14-9-13(10-23-11-14)17-4-2-7-27(17)19-6-8-28-20(26-19)15(12-24-28)21(30)25-16-3-1-5-18(16)29/h6,8-12,16-18,29H,1-5,7H2,(H,25,30)/t16-,17-,18+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma, Inc. US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mixture c...				US Patent US9796724 (2017) BindingDB Entry DOI: 10.7270/Q27M0B21
					More data for this Ligand-Target Pair