Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase JAK2 [828-1132] (Homo sapiens (Human)) | BDBM197716![]() (US9216984, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | 7.8 | 25 |
Incyte Corporation; Incyte Holdings Corporation US Patent | Assay Description The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,... | US Patent US9216984 (2015) BindingDB Entry DOI: 10.7270/Q26M35PV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 [828-1132] (Homo sapiens (Human)) | BDBM197716![]() (US9216984, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | 7.8 | 25 |
Incyte Corporation; Incyte Holdings Corporation US Patent | Assay Description The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,... | US Patent US9216984 (2015) BindingDB Entry DOI: 10.7270/Q26M35PV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 [828-1132] (Homo sapiens (Human)) | BDBM197716![]() (US9216984, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | 7.8 | 25 |
Incyte Corporation; Incyte Holdings Corporation US Patent | Assay Description The compounds of the invention were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al.,... | US Patent US9216984 (2015) BindingDB Entry DOI: 10.7270/Q26M35PV | |||||||||||
More data for this Ligand-Target Pair |