Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50132424'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50132424 (3-[2-Oxo-2-(1H-pyrrol-2-yl)-eth-(Z)-ylidene]-5-(th...) Show SMILES O=C(\C=C1/C(=O)Nc2ccc(cc12)C(=O)c1cccs1)c1ccc[nH]1 Show InChI InChI=1S/C19H12N2O3S/c22-16(15-3-1-7-20-15)10-13-12-9-11(5-6-14(12)21-19(13)24)18(23)17-4-2-8-25-17/h1-10,20H,(H,21,24)/b13-10-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.				Bioorg Med Chem Lett 13: 3105-10 (2003) BindingDB Entry DOI: 10.7270/Q2833RDR
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