Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM243366'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM243366 (4-{5-[3-(Thiazol-2- ylamino)-phenyl]oxazol- 2-yl}-...) Show SMILES O=C1NCCN(c2ncc(o2)-c2cccc(Nc3nccs3)c2)C11CC1 Show InChI InChI=1S/C18H17N5O2S/c24-15-18(4-5-18)23(8-6-19-15)17-21-11-14(25-17)12-2-1-3-13(10-12)22-16-20-7-9-26-16/h1-3,7,9-11H,4-6,8H2,(H,19,24)(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	7.8	25
AB SCIENCE US Patent					Assay Description SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...				US Patent US10053455 (2018) BindingDB Entry DOI: 10.7270/Q27946PV
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