Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Urotensin-2 receptor' and Ligand = 'BDBM50302269'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50302269 ((R)-N-(4-(3,4-dimethoxyphenyl)-4-(4-(4-ethylpipera...) Show SMILES CCN1CCN(CC1)c1cccc2C(=O)N(Cc12)[C@H](CCCNS(=O)(=O)c1cnc[nH]1)c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C29H38N6O5S/c1-4-33-13-15-34(16-14-33)25-8-5-7-22-23(25)19-35(29(22)36)24(21-10-11-26(39-2)27(17-21)40-3)9-6-12-32-41(37,38)28-18-30-20-31-28/h5,7-8,10-11,17-18,20,24,32H,4,6,9,12-16,19H2,1-3H3,(H,30,31)/t24-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]urotensin 2 from urotensin 2 receptor in human RMS13 cells by scintillation proximity assay				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (RAT)	BDBM50302269 ((R)-N-(4-(3,4-dimethoxyphenyl)-4-(4-(4-ethylpipera...) Show SMILES CCN1CCN(CC1)c1cccc2C(=O)N(Cc12)[C@H](CCCNS(=O)(=O)c1cnc[nH]1)c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C29H38N6O5S/c1-4-33-13-15-34(16-14-33)25-8-5-7-22-23(25)19-35(29(22)36)24(21-10-11-26(39-2)27(17-21)40-3)9-6-12-32-41(37,38)28-18-30-20-31-28/h5,7-8,10-11,17-18,20,24,32H,4,6,9,12-16,19H2,1-3H3,(H,30,31)/t24-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50302269 ((R)-N-(4-(3,4-dimethoxyphenyl)-4-(4-(4-ethylpipera...) Show SMILES CCN1CCN(CC1)c1cccc2C(=O)N(Cc12)[C@H](CCCNS(=O)(=O)c1cnc[nH]1)c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C29H38N6O5S/c1-4-33-13-15-34(16-14-33)25-8-5-7-22-23(25)19-35(29(22)36)24(21-10-11-26(39-2)27(17-21)40-3)9-6-12-32-41(37,38)28-18-30-20-31-28/h5,7-8,10-11,17-18,20,24,32H,4,6,9,12-16,19H2,1-3H3,(H,30,31)/t24-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at urotensin 2 receptor in human RMS13 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobilization aft...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair