Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM473607'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM473607 (US10844062, Example 43) Show SMILES CC(C)(C#N)c1cc(F)cc(c1)C(=O)Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F Show InChI InChI=1S/C27H19F3N8O/c1-27(2,11-31)15-8-14(9-16(28)10-15)26(39)37-19-6-5-18(29)22(20(19)30)38-24-17(4-3-7-32-24)21-23-25(35-12-33-21)36-13-34-23/h3-10,12-13H,1-2H3,(H,32,38)(H,37,39)(H,33,34,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
Incheon University Industry Academic Cooperation Foundation; Samjin Pharmaceutical Co., Ltd.; Bamichem Co., Ltd. US Patent					Assay Description The inhibitory activities of the compounds of the present invention against VEGFR-2 tyrosine kinase were analyzed using ADP-Glo™ kinase assay kit com...				US Patent US10844062 (2020) BindingDB Entry DOI: 10.7270/Q2NG4TRN
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