Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50134430'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50134430 (CHEMBL3747248) Show SMILES COc1cccc(Nc2c(cnc3c(C(C)C)c(nn23)S(C)(=O)=O)C(N)=O)c1 Show InChI InChI=1S/C18H21N5O4S/c1-10(2)14-17-20-9-13(15(19)24)16(23(17)22-18(14)28(4,25)26)21-11-6-5-7-12(8-11)27-3/h5-10,21H,1-4H3,(H2,19,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Research Center Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assay				Bioorg Med Chem Lett 26: 454-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.093 BindingDB Entry DOI: 10.7270/Q2X92D4M
					More data for this Ligand-Target Pair