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Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50256143'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50256143
PNG
(CHEMBL4079300)
Show SMILES COc1cccc(Nc2cc(nc3CCN\C(=N/C#N)c23)-c2cccc(OC)c2)c1
Show InChI InChI=1S/C23H21N5O2/c1-29-17-7-3-5-15(11-17)20-13-21(27-16-6-4-8-18(12-16)30-2)22-19(28-20)9-10-25-23(22)26-14-24/h3-8,11-13H,9-10H2,1-2H3,(H,25,26)(H,27,28)
PDB

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Medicinal Chemistry& Screening ,?Pharmacokinetics& Metabolism , and§Experimental Dermatology , Almirall S.A., Centro de Investigación y Desarrollo , Crta. Laureà Miró 408-410 , Sant Feliu de

Curated by ChEMBL


Assay Description
Inhibition of Vascular endothelial growth factor receptor 2

J Med Chem 61: 2472-2489 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01751
BindingDB Entry DOI: 10.7270/Q2HQ42BB
More data for this
Ligand-Target Pair