Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4D' and Ligand = 'BDBM50304409'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50304409 (CHEMBL595959 | cis-2-{2-[2-(1H-Imidazol-1-yl)ethox...) Show SMILES COc1ccc(cc1OC)C1=NN(CCOCCn2ccnc2)C(=O)[C@@H]2CC=CC[C@H]12 |r,c:29,t:11| Show InChI InChI=1S/C23H28N4O4/c1-29-20-8-7-17(15-21(20)30-2)22-18-5-3-4-6-19(18)23(28)27(25-22)12-14-31-13-11-26-10-9-24-16-26/h3-4,7-10,15-16,18-19H,5-6,11-14H2,1-2H3/t18-,19+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 601-8550 Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysis				Bioorg Med Chem 17: 6959-70 (2009) Article DOI: 10.1016/j.bmc.2009.08.014 BindingDB Entry DOI: 10.7270/Q2WH2Q26
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