BindingDB PrimarySearch

Found 11 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50036217
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tubulin beta-2B chain (Bos taurus)	BDBM50035218 (CHEMBL61 \| PODOFILOX \| Podophyllinic acid lactone ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmaceutical Chemistry Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 36: 1146-56 (1993) BindingDB Entry DOI: 10.7270/Q2BV7H8S
Institute of Pharmaceutical Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Tubulin beta-2B chain (Bos taurus)	BDBM50041130 (6-Methoxy-2-phenyl-1H-quinolin-4-one \| CHEMBL14120...) Show SMILES COc1ccc2nc(cc(O)c2c1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmaceutical Chemistry Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 36: 1146-56 (1993) BindingDB Entry DOI: 10.7270/Q2BV7H8S
Institute of Pharmaceutical Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50044966 (6-Chloro-2-phenyl-1H-quinolin-4-one \| CHEMBL15845) Show SMILES Oc1cc(nc2ccc(Cl)cc12)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmaceutical Chemistry Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 36: 1146-56 (1993) BindingDB Entry DOI: 10.7270/Q2BV7H8S
Institute of Pharmaceutical Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50044963 (6-Fluoro-2-phenyl-1H-quinolin-4-one \| CHEMBL16098) Show SMILES Oc1cc(nc2ccc(F)cc12)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmaceutical Chemistry Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 36: 1146-56 (1993) BindingDB Entry DOI: 10.7270/Q2BV7H8S
Institute of Pharmaceutical Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50044960 (7-Hydroxy-2-phenyl-1H-quinolin-4-one \| CHEMBL15634) Show SMILES Oc1ccc2c(O)cc(nc2c1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmaceutical Chemistry Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 36: 1146-56 (1993) BindingDB Entry DOI: 10.7270/Q2BV7H8S
Institute of Pharmaceutical Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50044969 (7-Fluoro-2-phenyl-1H-quinolin-4-one \| CHEMBL279539) Show SMILES Oc1cc(nc2cc(F)ccc12)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmaceutical Chemistry Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 36: 1146-56 (1993) BindingDB Entry DOI: 10.7270/Q2BV7H8S
Institute of Pharmaceutical Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50044962 (7-Methoxy-2-phenyl-1H-quinolin-4-one \| CHEMBL15831) Show SMILES COc1ccc2c(O)cc(nc2c1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmaceutical Chemistry Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 36: 1146-56 (1993) BindingDB Entry DOI: 10.7270/Q2BV7H8S
Institute of Pharmaceutical Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50044968 (8-Fluoro-2-phenyl-1H-quinolin-4-one \| CHEMBL15450) Show SMILES Oc1cc(nc2c(F)cccc12)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmaceutical Chemistry Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 36: 1146-56 (1993) BindingDB Entry DOI: 10.7270/Q2BV7H8S
Institute of Pharmaceutical Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50044961 (6-Hydroxy-2-phenyl-1H-quinolin-4-one \| CHEMBL27653...) Show SMILES Oc1ccc2nc(cc(O)c2c1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmaceutical Chemistry Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 36: 1146-56 (1993) BindingDB Entry DOI: 10.7270/Q2BV7H8S
Institute of Pharmaceutical Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50044965 (1-Methyl-2-phenyl-1H-quinolin-4-one \| CHEMBL277048) Show SMILES Cn1c(cc(=O)c2ccccc12)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmaceutical Chemistry Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 36: 1146-56 (1993) BindingDB Entry DOI: 10.7270/Q2BV7H8S
Institute of Pharmaceutical Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bos taurus)	BDBM50044970 (8-Methoxy-2-phenyl-1H-quinolin-4-one \| CHEMBL15706) Show SMILES COc1cccc2c(O)cc(nc12)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmaceutical Chemistry Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization				J Med Chem 36: 1146-56 (1993) BindingDB Entry DOI: 10.7270/Q2BV7H8S
Institute of Pharmaceutical Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair