Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tubulin beta-2B chain (Bos taurus) | BDBM50035218 (CHEMBL61 | PODOFILOX | Podophyllinic acid lactone ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy Curated by ChEMBL | Assay Description Inhibition of tubulin polymerization | J Med Chem 37: 1126-35 (1994) BindingDB Entry DOI: 10.7270/Q2ZC81XN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tubulin beta-2B chain (Bos taurus) | BDBM50035218 (CHEMBL61 | PODOFILOX | Podophyllinic acid lactone ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL | Assay Description Inhibition of bovine tubulin polymerization | J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tubulin beta-2B chain (Bos taurus) | BDBM50035218 (CHEMBL61 | PODOFILOX | Podophyllinic acid lactone ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Chemistry Curated by ChEMBL | Assay Description Inhibition of tubulin polymerization | J Med Chem 36: 1146-56 (1993) BindingDB Entry DOI: 10.7270/Q2BV7H8S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |