Compile Data Set for Download or QSAR

Found 92 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 8831   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421849 ((5S)-7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)ph...) Show SMILES Cn1cnc(n1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(C4CCNC(C4)C(F)(F)F)c3c2)C1 |r,t:14| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421854 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3nnc(C)o3)C2)C1=O |r,c:35| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421835 (US10493060, Example GDC-0994) Show SMILES Cn1nccc1Nc1cccc(n1)-c1ccn(C(CO)c2ccc(Cl)c(F)c2)c(=O)c1 Show InChI InChI=1S/C22H19ClFN5O2/c1-28-21(7-9-25-28)27-20-4-2-3-18(26-20)14-8-10-29(22(31)12-14)19(13-30)15-5-6-16(23)17(24)11-15/h2-12,19,30H,13H2,1H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421835 (US10493060, Example GDC-0994) Show SMILES Cn1nccc1Nc1cccc(n1)-c1ccn(C(CO)c2ccc(Cl)c(F)c2)c(=O)c1 Show InChI InChI=1S/C22H19ClFN5O2/c1-28-21(7-9-25-28)27-20-4-2-3-18(26-20)14-8-10-29(22(31)12-14)19(13-30)15-5-6-16(23)17(24)11-15/h2-12,19,30H,13H2,1H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421836 (US10493060, Example BVD-523) Show SMILES CC(C)Nc1cc(-c2c[nH]c(c2)C(=O)NC(CO)c2cccc(Cl)c2)c(Cl)cn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421836 (US10493060, Example BVD-523) Show SMILES CC(C)Nc1cc(-c2c[nH]c(c2)C(=O)NC(CO)c2cccc(Cl)c2)c(Cl)cn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421837 (US10493060, Example SCH772984) Show SMILES O=C(CN1CCC(C1)C(=O)Nc1ccc2[nH]nc(-c3ccncc3)c2c1)N1CCN(CC1)c1ccc(cc1)-c1ncccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421837 (US10493060, Example SCH772984) Show SMILES O=C(CN1CCC(C1)C(=O)Nc1ccc2[nH]nc(-c3ccncc3)c2c1)N1CCN(CC1)c1ccc(cc1)-c1ncccn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421838 (2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-yl)-7...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CCC2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |c:35| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421838 (2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-yl)-7...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CCC2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |c:35| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421840 (2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-yl)-7...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CCC2(CCN(CC(=O)N3CCN(CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421840 (2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-yl)-7...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CCC2(CCN(CC(=O)N3CCN(CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421843 (7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phenyl)...) Show SMILES Cc1cc(ccn1)-c1n[nH]c2ccc(cc12)N1CCC2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |c:32| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421843 (7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phenyl)...) Show SMILES Cc1cc(ccn1)-c1n[nH]c2ccc(cc12)N1CCC2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |c:32| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421844 (7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phenyl)...) Show SMILES Cc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CCC2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |c:32| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421844 (7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phenyl)...) Show SMILES Cc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CCC2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |c:32| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421845 ((S)-7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phe...) Show SMILES Cc1cc(ccn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r,c:32| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421845 ((S)-7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phe...) Show SMILES Cc1cc(ccn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r,c:32| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421846 ((R)-7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phe...) Show SMILES Cc1cc(ccn1)-c1n[nH]c2ccc(cc12)N1CC[C@@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r,c:32| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421847 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1nn(c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O)C(c1ccccc1)(c1ccccc1)c1ccccc1 |r,c:35| Show InChI InChI=1S/C57H55N9O3/c1-40(2)69-51-26-23-44(36-58-51)53-49-35-48(24-25-50(49)66(60-53)57(45-13-7-4-8-14-45,46-15-9-5-10-16-46)47-17-11-6-12-18-47)65-34-30-56(55(65)68)29-33-63(38-56)37-52(67)64-31-27-42(28-32-64)41-19-21-43(22-20-41)54-59-39-62(3)61-54/h4-27,35-36,39-40H,28-34,37-38H2,1-3H3/t56-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421847 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1nn(c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O)C(c1ccccc1)(c1ccccc1)c1ccccc1 |r,c:35| Show InChI InChI=1S/C57H55N9O3/c1-40(2)69-51-26-23-44(36-58-51)53-49-35-48(24-25-50(49)66(60-53)57(45-13-7-4-8-14-45,46-15-9-5-10-16-46)47-17-11-6-12-18-47)65-34-30-56(55(65)68)29-33-63(38-56)37-52(67)64-31-27-42(28-32-64)41-19-21-43(22-20-41)54-59-39-62(3)61-54/h4-27,35-36,39-40H,28-34,37-38H2,1-3H3/t56-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421849 ((5S)-7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)ph...) Show SMILES Cn1cnc(n1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(C4CCNC(C4)C(F)(F)F)c3c2)C1 |r,t:14| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421851 ((S)-7-(2-(4-(4-(1H-1,2,3-Triazol-1-yl)phenyl)-3,6-...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-n3ccnn3)C2)C1=O |r,c:35| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421851 ((S)-7-(2-(4-(4-(1H-1,2,3-Triazol-1-yl)phenyl)-3,6-...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-n3ccnn3)C2)C1=O |r,c:35| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421852 ((S)-2-(3-(6-isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3cn(C)nn3)C2)C1=O |r,c:35| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421852 ((S)-2-(3-(6-isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3cn(C)nn3)C2)C1=O |r,c:35| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421853 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421853 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421854 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3nnc(C)o3)C2)C1=O |r,c:35| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421855 ((S)-7-(2-(4-(4-(5-(Ethylamino)-1,3,4-oxadiazol-2-y...) Show SMILES CCNc1nnc(o1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccc(OC(C)C)nc4)c3c2)C1 |r,t:16| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421855 ((S)-7-(2-(4-(4-(5-(Ethylamino)-1,3,4-oxadiazol-2-y...) Show SMILES CCNc1nnc(o1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccc(OC(C)C)nc4)c3c2)C1 |r,t:16| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421856 ((S)-7-(2-(4-(4-(5-(Ethylamino)-1,3,4-thiadiazol-2-...) Show SMILES CCNc1nnc(s1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccc(OC(C)C)nc4)c3c2)C1 |r,t:16| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421856 ((S)-7-(2-(4-(4-(5-(Ethylamino)-1,3,4-thiadiazol-2-...) Show SMILES CCNc1nnc(s1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccc(OC(C)C)nc4)c3c2)C1 |r,t:16| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421857 ((S)-7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phe...) Show SMILES Cn1cnc(n1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccnc(c4)C(F)(F)F)c3c2)C1 |r,t:14| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421857 ((S)-7-(2-(4-(4-(1-Methyl-1H-1,2,4-triazol-3-yl)phe...) Show SMILES Cn1cnc(n1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccnc(c4)C(F)(F)F)c3c2)C1 |r,t:14| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421859 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncccn3)C2)C1=O |r,c:35| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421859 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncccn3)C2)C1=O |r,c:35| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421860 ((S)-7-(2-(4-(4-(5-Fluoropyrimidin-2-yl)phenyl)-3,6...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncc(F)cn3)C2)C1=O |r,c:35| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421860 ((S)-7-(2-(4-(4-(5-Fluoropyrimidin-2-yl)phenyl)-3,6...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncc(F)cn3)C2)C1=O |r,c:35| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421861 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(CC3)C34CC(C3)(C4)c3ncn(C)n3)C2)C1=O |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421863 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3cn(C)cn3)C2)C1=O |r,c:35| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421865 ((S)-7-(2-(4-(4-(5-Fluoropyrimidin-2-yl)phenyl)-3,6...) Show SMILES Fc1cnc(nc1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccnc(c4)C(F)(F)F)c3c2)C1 |r,t:15| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421865 ((S)-7-(2-(4-(4-(5-Fluoropyrimidin-2-yl)phenyl)-3,6...) Show SMILES Fc1cnc(nc1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccnc(c4)C(F)(F)F)c3c2)C1 |r,t:15| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421866 ((S)-2-(3-(4-Fluorophenyl)-1H-indazol-5-yl)-7-(2-(4...) Show SMILES Cn1cnc(n1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccc(F)cc4)c3c2)C1 |r,t:14| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421866 ((S)-2-(3-(4-Fluorophenyl)-1H-indazol-5-yl)-7-(2-(4...) Show SMILES Cn1cnc(n1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccc(F)cc4)c3c2)C1 |r,t:14| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421867 ((S)-2-(3-(2-Isopropoxypyridin-4-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1cc(ccn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r,c:35| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421867 ((S)-2-(3-(2-Isopropoxypyridin-4-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1cc(ccn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCC(=CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r,c:35| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM421868 ((S)-2-(3-(3-Fluoropyridin-4-yl)-1H-indazol-5-yl)-7...) Show SMILES Cn1cnc(n1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccncc4F)c3c2)C1 |r,t:14| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421868 ((S)-2-(3-(3-Fluoropyridin-4-yl)-1H-indazol-5-yl)-7...) Show SMILES Cn1cnc(n1)-c1ccc(cc1)C1=CCN(CC1)C(=O)CN1CC[C@]2(CCN(C2=O)c2ccc3[nH]nc(-c4ccncc4F)c3c2)C1 |r,t:14| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421869 ((S)-2-(3-(6-Isopropoxypyridin-3-yl)-1H-indazol-5-y...) Show SMILES CC(C)Oc1ccc(cn1)-c1n[nH]c2ccc(cc12)N1CC[C@]2(CCN(CC(=O)N3CCN(CC3)c3ccc(cc3)-c3ncn(C)n3)C2)C1=O |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
					More data for this Ligand-Target Pair

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