Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM421835'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM421835 (US10493060, Example GDC-0994) Show SMILES Cn1nccc1Nc1cccc(n1)-c1ccn(C(CO)c2ccc(Cl)c(F)c2)c(=O)c1 Show InChI InChI=1S/C22H19ClFN5O2/c1-28-21(7-9-25-28)27-20-4-2-3-18(26-20)14-8-10-29(22(31)12-14)19(13-30)15-5-6-16(23)17(24)11-15/h2-12,19,30H,13H2,1H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Recurium IP Holdings, LLC US Patent					Assay Description Activated ERK1 and ERK2 activity was determined in a Mobility Shift Assay (MSA) format as follows: Compound and kinase solution were prepared with as...				US Patent US10493060 (2019) BindingDB Entry DOI: 10.7270/Q2SQ92R3
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