Found 170 hits Enz. Inhib. hit(s) with all data for assayid = 2 entry = 11501 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Receptor-type tyrosine-protein kinase FLT3 [D835H]
(Homo sapiens (Human)) | BDBM621080
(N-(6-(6-(1-methyl- cyclopropyl)imidazo- [1,2-a]pyr...)Show SMILES CC1(CC1)c1ccc2ncc(-c3cccc(NC4CCC5(CNC5)C4)n3)n2c1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.170 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621080
(N-(6-(6-(1-methyl- cyclopropyl)imidazo- [1,2-a]pyr...)Show SMILES CC1(CC1)c1ccc2ncc(-c3cccc(NC4CCC5(CNC5)C4)n3)n2c1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0980 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 (D835Y)
(Homo sapiens (Human)) | BDBM621080
(N-(6-(6-(1-methyl- cyclopropyl)imidazo- [1,2-a]pyr...)Show SMILES CC1(CC1)c1ccc2ncc(-c3cccc(NC4CCC5(CNC5)C4)n3)n2c1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM621080
(N-(6-(6-(1-methyl- cyclopropyl)imidazo- [1,2-a]pyr...)Show SMILES CC1(CC1)c1ccc2ncc(-c3cccc(NC4CCC5(CNC5)C4)n3)n2c1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.370 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621080
(N-(6-(6-(1-methyl- cyclopropyl)imidazo- [1,2-a]pyr...)Show SMILES CC1(CC1)c1ccc2ncc(-c3cccc(NC4CCC5(CNC5)C4)n3)n2c1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0340 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835H]
(Homo sapiens (Human)) | BDBM621098
(6-(6-(difluorometh- oxy)imidazo[1,2-a]- pyridin-3-...)Show SMILES FC(F)Oc1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621098
(6-(6-(difluorometh- oxy)imidazo[1,2-a]- pyridin-3-...)Show SMILES FC(F)Oc1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0120 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 (D835Y)
(Homo sapiens (Human)) | BDBM621098
(6-(6-(difluorometh- oxy)imidazo[1,2-a]- pyridin-3-...)Show SMILES FC(F)Oc1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0470 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM621098
(6-(6-(difluorometh- oxy)imidazo[1,2-a]- pyridin-3-...)Show SMILES FC(F)Oc1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621098
(6-(6-(difluorometh- oxy)imidazo[1,2-a]- pyridin-3-...)Show SMILES FC(F)Oc1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0110 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835H]
(Homo sapiens (Human)) | BDBM621166
(N-((3S,4S)-4-fluoro- pyrrolidin-3-yl)-6-(6-(1- met...)Show SMILES Cn1cc(cn1)-c1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621166
(N-((3S,4S)-4-fluoro- pyrrolidin-3-yl)-6-(6-(1- met...)Show SMILES Cn1cc(cn1)-c1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 (D835Y)
(Homo sapiens (Human)) | BDBM621166
(N-((3S,4S)-4-fluoro- pyrrolidin-3-yl)-6-(6-(1- met...)Show SMILES Cn1cc(cn1)-c1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM621166
(N-((3S,4S)-4-fluoro- pyrrolidin-3-yl)-6-(6-(1- met...)Show SMILES Cn1cc(cn1)-c1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.540 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621166
(N-((3S,4S)-4-fluoro- pyrrolidin-3-yl)-6-(6-(1- met...)Show SMILES Cn1cc(cn1)-c1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0120 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835H]
(Homo sapiens (Human)) | BDBM621167
(1-(4-(3-(6-(((3S,4S)-4- fluoropyrrolidin-3-yl)- am...)Show SMILES CC(C)(O)Cn1cc(cn1)-c1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621167
(1-(4-(3-(6-(((3S,4S)-4- fluoropyrrolidin-3-yl)- am...)Show SMILES CC(C)(O)Cn1cc(cn1)-c1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0590 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 (D835Y)
(Homo sapiens (Human)) | BDBM621167
(1-(4-(3-(6-(((3S,4S)-4- fluoropyrrolidin-3-yl)- am...)Show SMILES CC(C)(O)Cn1cc(cn1)-c1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM621167
(1-(4-(3-(6-(((3S,4S)-4- fluoropyrrolidin-3-yl)- am...)Show SMILES CC(C)(O)Cn1cc(cn1)-c1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.310 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621167
(1-(4-(3-(6-(((3S,4S)-4- fluoropyrrolidin-3-yl)- am...)Show SMILES CC(C)(O)Cn1cc(cn1)-c1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0160 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835H]
(Homo sapiens (Human)) | BDBM621168
(6-(6-(1-cyclopropyl-1H- pyrazol-4-yl)imidazo- [1,2...)Show SMILES F[C@H]1CNC[C@@H]1Nc1cccc(n1)-c1cnc2ccc(cn12)-c1cnn(c1)C1CC1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621168
(6-(6-(1-cyclopropyl-1H- pyrazol-4-yl)imidazo- [1,2...)Show SMILES F[C@H]1CNC[C@@H]1Nc1cccc(n1)-c1cnc2ccc(cn12)-c1cnn(c1)C1CC1 |r| | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 (D835Y)
(Homo sapiens (Human)) | BDBM621168
(6-(6-(1-cyclopropyl-1H- pyrazol-4-yl)imidazo- [1,2...)Show SMILES F[C@H]1CNC[C@@H]1Nc1cccc(n1)-c1cnc2ccc(cn12)-c1cnn(c1)C1CC1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM621168
(6-(6-(1-cyclopropyl-1H- pyrazol-4-yl)imidazo- [1,2...)Show SMILES F[C@H]1CNC[C@@H]1Nc1cccc(n1)-c1cnc2ccc(cn12)-c1cnn(c1)C1CC1 |r| | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621168
(6-(6-(1-cyclopropyl-1H- pyrazol-4-yl)imidazo- [1,2...)Show SMILES F[C@H]1CNC[C@@H]1Nc1cccc(n1)-c1cnc2ccc(cn12)-c1cnn(c1)C1CC1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0110 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835H]
(Homo sapiens (Human)) | BDBM621115
(US20230303563, Compound 117)Show SMILES OCc1cc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2cc1C1CC1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0380 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621115
(US20230303563, Compound 117)Show SMILES OCc1cc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2cc1C1CC1 |r| | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0110 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 (D835Y)
(Homo sapiens (Human)) | BDBM621115
(US20230303563, Compound 117)Show SMILES OCc1cc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2cc1C1CC1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0770 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM621115
(US20230303563, Compound 117)Show SMILES OCc1cc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2cc1C1CC1 |r| | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621115
(US20230303563, Compound 117)Show SMILES OCc1cc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2cc1C1CC1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.00700 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835H]
(Homo sapiens (Human)) | BDBM621116
(2-(3-(6-(((3S,4S)-4- fluoropyrrolidin-3- yl)amino)...)Show SMILES CC(C)(O)c1cn2c(cnc2cc1CO)-c1cccc(N[C@H]2CNC[C@@H]2F)n1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.180 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621116
(2-(3-(6-(((3S,4S)-4- fluoropyrrolidin-3- yl)amino)...)Show SMILES CC(C)(O)c1cn2c(cnc2cc1CO)-c1cccc(N[C@H]2CNC[C@@H]2F)n1 |r| | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0520 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 (D835Y)
(Homo sapiens (Human)) | BDBM621116
(2-(3-(6-(((3S,4S)-4- fluoropyrrolidin-3- yl)amino)...)Show SMILES CC(C)(O)c1cn2c(cnc2cc1CO)-c1cccc(N[C@H]2CNC[C@@H]2F)n1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM621116
(2-(3-(6-(((3S,4S)-4- fluoropyrrolidin-3- yl)amino)...)Show SMILES CC(C)(O)c1cn2c(cnc2cc1CO)-c1cccc(N[C@H]2CNC[C@@H]2F)n1 |r| | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0750 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621116
(2-(3-(6-(((3S,4S)-4- fluoropyrrolidin-3- yl)amino)...)Show SMILES CC(C)(O)c1cn2c(cnc2cc1CO)-c1cccc(N[C@H]2CNC[C@@H]2F)n1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.00900 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835H]
(Homo sapiens (Human)) | BDBM621117
(2-(3-(6-(((3S,4S)-4- fluoropiperidin-3- yl)amino)p...)Show SMILES CC(C)(O)c1cn2c(cnc2cc1CO)-c1cccc(N[C@H]2CNCC[C@@H]2F)n1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621117
(2-(3-(6-(((3S,4S)-4- fluoropiperidin-3- yl)amino)p...)Show SMILES CC(C)(O)c1cn2c(cnc2cc1CO)-c1cccc(N[C@H]2CNCC[C@@H]2F)n1 |r| | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0340 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 (D835Y)
(Homo sapiens (Human)) | BDBM621117
(2-(3-(6-(((3S,4S)-4- fluoropiperidin-3- yl)amino)p...)Show SMILES CC(C)(O)c1cn2c(cnc2cc1CO)-c1cccc(N[C@H]2CNCC[C@@H]2F)n1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM621117
(2-(3-(6-(((3S,4S)-4- fluoropiperidin-3- yl)amino)p...)Show SMILES CC(C)(O)c1cn2c(cnc2cc1CO)-c1cccc(N[C@H]2CNCC[C@@H]2F)n1 |r| | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.180 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621117
(2-(3-(6-(((3S,4S)-4- fluoropiperidin-3- yl)amino)p...)Show SMILES CC(C)(O)c1cn2c(cnc2cc1CO)-c1cccc(N[C@H]2CNCC[C@@H]2F)n1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0170 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835H]
(Homo sapiens (Human)) | BDBM621123
(US20230303563, Compound 165)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621123
(US20230303563, Compound 165)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0250 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 (D835Y)
(Homo sapiens (Human)) | BDBM621123
(US20230303563, Compound 165)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM621123
(US20230303563, Compound 165)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621123
(US20230303563, Compound 165)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNC[C@@H]4F)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.00700 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835H]
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0410 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 (D835Y)
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.170 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621125
((R)-N-(6-(6- (difluoromethyl)imidazo[1,2- a]pyridi...)Show SMILES FC(F)c1ccc2ncc(-c3cccc(N[C@H]4CNCC44CC4)n3)n2c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
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