Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet-activating factor acetylhydrolase (Homo sapiens (Human)) | BDBM50125265 (CHEMBL204021 | N-(2-Diethylamino-ethyl)-2-[2-(4-fl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de La R£union Curated by ChEMBL | Assay Description Inhibition of human Lp-PLA2 | Bioorg Med Chem Lett 28: 787-792 (2018) Article DOI: 10.1016/j.bmcl.2017.12.052 BindingDB Entry DOI: 10.7270/Q2GB26N5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |