Found 28 hits Enz. Inhib. hit(s) with all data for assayid = 5 entry = 50047005 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143076
(CHEMBL3758587)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3ccc(C)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O4/c1-10-3-5-13-14(7-10)20(27)24(19(13)26)16-6-4-12(8-15(16)21)23-18(25)17-11(2)28-9-22-17/h3-9H,1-2H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 198 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143148
(CHEMBL3759376)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3ccc(F)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClFN4O3/c1-9-8-22-24-16(9)17(26)23-11-3-5-15(14(20)7-11)25-18(27)12-4-2-10(21)6-13(12)19(25)28/h2-8H,1H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143083
(CHEMBL3759424)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O4/c1-10-4-3-5-13-16(10)20(27)24(19(13)26)15-7-6-12(8-14(15)21)23-18(25)17-11(2)28-9-22-17/h3-9H,1-2H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 519 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143085
(CHEMBL3759846)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 Show InChI InChI=1S/C18H12ClN5O3/c1-9-8-21-23-14(9)16(25)22-10-4-5-13(12(19)7-10)24-17(26)11-3-2-6-20-15(11)18(24)27/h2-8H,1H3,(H,21,23)(H,22,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143086
(CHEMBL3759289)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3ccc(Cl)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2N3O4/c1-9-16(22-8-28-9)17(25)23-11-3-5-15(14(21)7-11)24-18(26)12-4-2-10(20)6-13(12)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 405 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143144
(CHEMBL3759867)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2N3O4/c1-9-16(22-8-28-9)17(25)23-10-5-6-14(13(21)7-10)24-18(26)11-3-2-4-12(20)15(11)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 983 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143145
(CHEMBL3759381)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3ccc(F)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11ClFN3O4/c1-9-16(22-8-28-9)17(25)23-11-3-5-15(14(20)7-11)24-18(26)12-4-2-10(21)6-13(12)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 642 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143146
(CHEMBL3759878)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11ClFN3O4/c1-9-16(22-8-28-9)17(25)23-10-5-6-14(12(20)7-10)24-18(26)11-3-2-4-13(21)15(11)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143147
(CHEMBL3759705)Show SMILES Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 Show InChI InChI=1S/C18H11ClN4O4/c1-9-14(21-8-27-9)16(24)22-10-4-5-13(12(19)7-10)23-17(25)11-3-2-6-20-15(11)18(23)26/h2-8H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.53E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143166
(CHEMBL3759038)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3ccc(C)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O3S/c1-10-3-5-13-14(7-10)20(27)24(19(13)26)16-6-4-12(8-15(16)21)23-18(25)17-11(2)28-9-22-17/h3-9H,1-2H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.12E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143165
(CHEMBL3760018)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H14ClN3O3S/c1-10-4-3-5-13-16(10)20(27)24(19(13)26)15-7-6-12(8-14(15)21)23-18(25)17-11(2)28-9-22-17/h3-9H,1-2H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.41E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143164
(CHEMBL3758216)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3ccc(Cl)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2N3O3S/c1-9-16(22-8-28-9)17(25)23-11-3-5-15(14(21)7-11)24-18(26)12-4-2-10(20)6-13(12)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.98E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143163
(CHEMBL3758756)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11Cl2N3O3S/c1-9-16(22-8-28-9)17(25)23-10-5-6-14(13(21)7-10)24-18(26)11-3-2-4-12(20)15(11)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143162
(CHEMBL3758967)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3ccc(F)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11ClFN3O3S/c1-9-16(22-8-28-9)17(25)23-11-3-5-15(14(20)7-11)24-18(26)12-4-2-10(21)6-13(12)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 306 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143161
(CHEMBL3759171)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H11ClFN3O3S/c1-9-16(22-8-28-9)17(25)23-10-5-6-14(12(20)7-10)24-18(26)11-3-2-4-13(21)15(11)19(24)27/h2-8H,1H3,(H,23,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 474 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143160
(CHEMBL3759573)Show SMILES Cc1scnc1C(=O)Nc1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 Show InChI InChI=1S/C18H11ClN4O3S/c1-9-14(21-8-27-9)16(24)22-10-4-5-13(12(19)7-10)23-17(25)11-3-2-6-20-15(11)18(23)26/h2-8H,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143159
(CHEMBL3759555)Show SMILES Cc1ccc2C(=O)N(C(=O)c2c1)c1ccc(NC(=O)c2nccn2C)cc1Cl Show InChI InChI=1S/C20H15ClN4O3/c1-11-3-5-13-14(9-11)20(28)25(19(13)27)16-6-4-12(10-15(16)21)23-18(26)17-22-7-8-24(17)2/h3-10H,1-2H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 602 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143158
(CHEMBL3758228)Show SMILES Cc1cccc2C(=O)N(C(=O)c12)c1ccc(NC(=O)c2nccn2C)cc1Cl Show InChI InChI=1S/C20H15ClN4O3/c1-11-4-3-5-13-16(11)20(28)25(19(13)27)15-7-6-12(10-14(15)21)23-18(26)17-22-8-9-24(17)2/h3-10H,1-2H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 506 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143157
(CHEMBL3759647)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3ccc(Cl)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2N4O3/c1-24-7-6-22-16(24)17(26)23-11-3-5-15(14(21)9-11)25-18(27)12-4-2-10(20)8-13(12)19(25)28/h2-9H,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.57E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143156
(CHEMBL3759990)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2N4O3/c1-24-8-7-22-16(24)17(26)23-10-5-6-14(13(21)9-10)25-18(27)11-3-2-4-12(20)15(11)19(25)28/h2-9H,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143155
(CHEMBL3758986)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3ccc(F)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClFN4O3/c1-24-7-6-22-16(24)17(26)23-11-3-5-15(14(20)9-11)25-18(27)12-4-2-10(21)8-13(12)19(25)28/h2-9H,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.07E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143154
(CHEMBL3758795)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClFN4O3/c1-24-8-7-22-16(24)17(26)23-10-5-6-14(12(20)9-10)25-18(27)11-3-2-4-13(21)15(11)19(25)28/h2-9H,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.09E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143153
(CHEMBL3759672)Show SMILES Cn1ccnc1C(=O)Nc1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 Show InChI InChI=1S/C18H12ClN5O3/c1-23-8-7-21-15(23)16(25)22-10-4-5-13(12(19)9-10)24-17(26)11-3-2-6-20-14(11)18(24)27/h2-9H,1H3,(H,22,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143152
(CHEMBL3759656)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3ccc(C)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H15ClN4O3/c1-10-3-5-13-14(7-10)20(28)25(19(13)27)16-6-4-12(8-15(16)21)23-18(26)17-11(2)9-22-24-17/h3-9H,1-2H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.75E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143151
(CHEMBL3759530)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C20H15ClN4O3/c1-10-4-3-5-13-16(10)20(28)25(19(13)27)15-7-6-12(8-14(15)21)23-18(26)17-11(2)9-22-24-17/h3-9H,1-2H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143150
(CHEMBL3759211)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3ccc(Cl)cc3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2N4O3/c1-9-8-22-24-16(9)17(26)23-11-3-5-15(14(21)7-11)25-18(27)12-4-2-10(20)6-13(12)19(25)28/h2-8H,1H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.38E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143149
(CHEMBL3758298)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2N4O3/c1-9-8-22-24-16(9)17(26)23-10-5-6-14(13(21)7-10)25-18(27)11-3-2-4-12(20)15(11)19(25)28/h2-8H,1H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143081
(CHEMBL3759028)Show SMILES Cc1cn[nH]c1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c(Cl)c1 Show InChI InChI=1S/C19H12ClFN4O3/c1-9-8-22-24-16(9)17(26)23-10-5-6-14(12(20)7-10)25-18(27)11-3-2-4-13(21)15(11)19(25)28/h2-8H,1H3,(H,22,24)(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Positive allosteric modulation of human mGlu4 receptor by cell based calcium mobilization |
Bioorg Med Chem Lett 26: 751-6 (2016)
Article DOI: 10.1016/j.bmcl.2015.12.104
BindingDB Entry DOI: 10.7270/Q261124T |
More data for this
Ligand-Target Pair | |
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