Compile Data Set for Download or QSAR

Found 1063 hits of ic50 for UniProtKB: P51946   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM50539763 (Adagrasib | Mrtx-849 | Mrtx849) Show SMILES CN1CCC[C@H]1COc1nc2CN(CCc2c(n1)N1CCN([C@@H](CC#N)C1)C(=O)C(F)=C)c1cccc2cccc(Cl)c12 Show InChI InChI=1S/C32H35ClFN7O2/c1-21(34)31(42)41-17-16-40(18-23(41)11-13-35)30-25-12-15-39(28-10-4-7-22-6-3-9-26(33)29(22)28)19-27(25)36-32(37-30)43-20-24-8-5-14-38(24)2/h3-4,6-7,9-10,23-24H,1,5,8,11-12,14-20H2,2H3/t23-,24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d2md00216g BindingDB Entry DOI: 10.7270/Q2DF6W53
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530357 (WO2022064009, Compound 136 | WO2022064009, Compoun...) Show SMILES C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1cccc(C)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	1.38	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530269 (WO2022064009, Compound 13) Show SMILES C[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r,wU:27.31,13.14,4.7,wD:21.23,1.0,(5.09,-6.89,;3.75,-7.66,;2.42,-6.89,;1.08,-7.66,;1.08,-9.2,;2.42,-9.97,;3.75,-9.2,;-.25,-9.97,;-1.58,-9.2,;-2.92,-9.97,;-4.25,-9.2,;-4.25,-7.66,;-5.58,-6.89,;-5.58,-5.35,;-6.92,-4.58,;-4.25,-4.58,;-2.92,-5.35,;-2.92,-6.89,;-1.58,-7.66,;-4.25,-3.04,;-5.58,-2.27,;-2.92,-2.27,;-1.58,-3.04,;-.25,-2.27,;-.25,-.73,;1.08,.04,;-1.58,.04,;-2.92,-.73,;-4.25,.04,;-4.25,1.58,;-5.58,2.35,;-6.92,1.58,;-6.92,.04,;-5.58,-.73,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	1.41	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530396 (WO2022064009, Compound 173) Show SMILES C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=N)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	1.66	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530309 (WO2022064009, Compound 70) Show SMILES C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	1.78	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530370 (WO2022064009, Compound 180a) Show SMILES C[C@H]1CN([C@H](C)c2nc(NC3CCOCC3)ncc12)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	2.09	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530318 (WO2022064009, Compound 82 | WO2022064009, Compound...) Show SMILES C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	2.14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530249 (WO2022064009, Compound 5) Show SMILES C[C@@H]1Cc2cnc(N[C@H]3CCN(C)C(=O)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	2.14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530318 (WO2022064009, Compound 82 | WO2022064009, Compound...) Show SMILES C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	2.14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530297 (WO2022064009, Compound 58) Show SMILES CCn1ccc(CNc2ncc3C[C@@H](C)N(Cc3n2)C(=O)[C@H]2CCN(C)C[C@@H]2c2ccccc2)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	2.34	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530245 (WO2022064009, Compound 1 | WO2022064009, Compound ...) Show SMILES C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	2.45	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530266 (WO2022064009, Compound 154 | WO2022064009, Compoun...) Show SMILES C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	2.51	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530260 (WO2022064009, Compound 37) Show SMILES CO[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r,wU:28.32,14.15,5.8,wD:22.24,2.1,(6.42,-7.66,;5.09,-6.89,;3.75,-7.66,;2.42,-6.89,;1.08,-7.66,;1.08,-9.2,;2.42,-9.97,;3.75,-9.2,;-.25,-9.97,;-1.58,-9.2,;-2.92,-9.97,;-4.25,-9.2,;-4.25,-7.66,;-5.58,-6.89,;-5.58,-5.35,;-6.92,-4.58,;-4.25,-4.58,;-2.92,-5.35,;-2.92,-6.89,;-1.58,-7.66,;-4.25,-3.04,;-5.58,-2.27,;-2.92,-2.27,;-1.58,-3.04,;-.25,-2.27,;-.25,-.73,;1.08,.04,;-1.58,.04,;-2.92,-.73,;-4.25,.04,;-4.25,1.58,;-5.58,2.35,;-6.92,1.58,;-6.92,.04,;-5.58,-.73,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	2.51	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530397 (WO2022064009, Compound 174) Show SMILES C[C@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	2.63	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530383 (WO2022064009, Compound 160) Show SMILES CC(C)N1CC[C@@H]([C@H](C1)c1cccc(Cl)c1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2C[C@H]1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	2.63	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530308 (WO2022064009, Compound 69) Show SMILES C[C@@H]1Cc2cnc(N[C@H]3CC[C@@H](CC3)OC(F)F)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r,wU:30.34,1.0,8.7,wD:24.26,11.14,(-6.92,-4.58,;-5.58,-5.35,;-5.58,-6.89,;-4.25,-7.66,;-4.25,-9.2,;-2.92,-9.97,;-1.58,-9.2,;-.25,-9.97,;1.08,-9.2,;1.08,-7.66,;2.42,-6.89,;3.75,-7.66,;3.75,-9.2,;2.42,-9.97,;5.08,-6.89,;6.42,-7.66,;6.42,-9.2,;7.75,-6.89,;-1.58,-7.66,;-2.92,-6.89,;-2.92,-5.35,;-4.25,-4.58,;-4.25,-3.04,;-5.58,-2.27,;-2.92,-2.27,;-1.58,-3.04,;-.25,-2.27,;-.25,-.73,;1.08,.04,;-1.58,.04,;-2.92,-.73,;-4.25,.04,;-4.25,1.58,;-5.58,2.35,;-6.92,1.58,;-6.92,.04,;-5.58,-.73,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	2.69	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530252 (WO2022064009, Compound 8) Show SMILES C[C@@H]1Cc2cnc(N[C@@H]3CCOC4(CCC4)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	2.69	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530305 (WO2022064009, Compound 66) Show SMILES CC(C)n1ccc(CNc2ncc3C[C@@H](C)N(Cc3n2)C(=O)[C@H]2CCN(C)C[C@@H]2c2ccccc2)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	2.75	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530280 (WO2022064009, Compound 29) Show SMILES C[C@@H]1Cc2cnc(NC3Cc4ccccc4C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	2.82	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530401 (WO2022064009, Compound 188) Show SMILES C[C@@H]1CN(Cc2nc(NC3CCOCC3)ncc12)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	2.82	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530310 (WO2022064009, Compound 71) Show SMILES C[C@@H]1Cc2cnc(N[C@@H](CO)c3ccccc3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	2.88	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM50363196 (CHEMBL1944698) Show SMILES CN1C\C=C\CCOc2cccc(c2)-c2ccnc(Nc3cccc(C1)c3)n2 |t:3| Show InChI InChI=1S/C23H24N4O/c1-27-13-3-2-4-14-28-21-10-6-8-19(16-21)22-11-12-24-23(26-22)25-20-9-5-7-18(15-20)17-27/h2-3,5-12,15-16H,4,13-14,17H2,1H3,(H,24,25,26)/b3-2+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Medical Center Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His6-tagged CDK7/cyclin H/N-terminal GST-tagged MAT1 expressed in baculovirus infected Sf21 in...				J Med Chem 59: 8667-8684 (2016) Article DOI: 10.1021/acs.jmedchem.6b00150 BindingDB Entry DOI: 10.7270/Q2G73GP8
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530335 (WO2022064009, Compound 120 | WO2022064009, Compoun...) Show SMILES C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccc(F)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	3.02	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530369 (WO2022064009, Compound 150) Show SMILES CCN1CC[C@@H]([C@H](C1)c1cccc(C)c1)C(=O)N1Cc2nc(NCc3ccn(C)n3)ncc2C[C@H]1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	3.16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530356 (WO2022064009, Compound 134) Show SMILES C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1cccc(C)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	3.16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530337 (WO2022064009, Compound 122b) Show SMILES C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccc(Cl)c(F)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	3.16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530286 (WO2022064009, Compound 156 | WO2022064009, Compoun...) Show SMILES C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	3.24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530256 (WO2022064009, Compound 12) Show SMILES C[C@@H]1Cc2cnc(N[C@H]3CC[C@H](O)CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r,wU:27.31,8.7,1.0,wD:21.23,11.11,(-6.92,-4.58,;-5.58,-5.35,;-5.58,-6.89,;-4.25,-7.66,;-4.25,-9.2,;-2.92,-9.97,;-1.58,-9.2,;-.25,-9.97,;1.08,-9.2,;1.08,-7.66,;2.42,-6.89,;3.75,-7.66,;5.08,-6.89,;3.75,-9.2,;2.42,-9.97,;-1.58,-7.66,;-2.92,-6.89,;-2.92,-5.35,;-4.25,-4.58,;-4.25,-3.04,;-5.58,-2.27,;-2.92,-2.27,;-1.58,-3.04,;-.25,-2.27,;-.25,-.73,;1.08,.04,;-1.58,.04,;-2.92,-.73,;-4.25,.04,;-4.25,1.58,;-5.58,2.35,;-6.92,1.58,;-6.92,.04,;-5.58,-.73,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	3.24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530424 (WO2022064009, Compound 210) Show SMILES C[C@@H]1Cc2cnc(NC3CCN(CC3)S(=O)(=O)C3CC3)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	3.31	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530423 (WO2022064009, Compound 209) Show SMILES C[C@@H]1Cc2cnc(NC3CCN(CC3)S(C)(=O)=O)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	3.31	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530299 (WO2022064009, Compound 60) Show SMILES C[C@@H]1Cc2cnc(NCC3CN(C)C=C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r,c:13| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	3.55	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530354 (WO2022064009, Compound 132) Show SMILES C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccc(Cl)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	3.63	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530339 (WO2022064009, Compound 126) Show SMILES C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1cccc(C)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	3.72	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530250 (WO2022064009, Compound 6) Show SMILES C[C@@H]1Cc2cnc(N[C@@H]3CCC(=O)N(C)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530316 (WO2022064009, Compound 78) Show SMILES C[C@@H]1Cc2cnc(Nc3ccnc(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	4.27	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530377 (WO2022064009, Compound 152) Show SMILES C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=O)[C@H]1CCN(CCO)C[C@@H]1c1cccc(C)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	4.37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530251 (WO2022064009, Compound 7) Show SMILES C[C@@H]1Cc2cnc(N[C@H]3CCC(=O)N(C)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	4.47	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530301 (WO2022064009, Compound 62 | WO2022064009, Compound...) Show SMILES C[C@@H]1Cc2cnc(NC[C@@H]3CCOC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	4.68	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530426 (WO2022064009, Compound 212) Show SMILES C[C@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)N1CCN(C)C[C@H]1c1cccc(F)c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	4.79	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530408 (WO2022064009, Compound 195b) Show SMILES C[C@@H]1Cc2cnc(NC3CCOCC3)nc2[C@H](C)N1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530342 (WO2022064009, Compound 129) Show SMILES C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1cccc(c1)C(F)(F)F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530247 (WO2022064009, Compound 3) Show SMILES C[C@@H]1Cc2cnc(NC3CC[C@@H](CC3)OCC3CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r,wU:31.36,1.0,wD:25.28,11.14,(-6.92,-4.58,;-5.58,-5.35,;-5.58,-6.89,;-4.25,-7.66,;-4.25,-9.2,;-2.92,-9.97,;-1.58,-9.2,;-.25,-9.97,;1.08,-9.2,;1.08,-7.66,;2.42,-6.89,;3.75,-7.66,;3.75,-9.2,;2.42,-9.97,;5.08,-6.89,;6.42,-7.66,;7.75,-6.89,;8.38,-5.48,;9.28,-6.73,;-1.58,-7.66,;-2.92,-6.89,;-2.92,-5.35,;-4.25,-4.58,;-4.25,-3.04,;-5.58,-2.27,;-2.92,-2.27,;-1.58,-3.04,;-.25,-2.27,;-.25,-.73,;1.08,.04,;-1.58,.04,;-2.92,-.73,;-4.25,.04,;-4.25,1.58,;-5.58,2.35,;-6.92,1.58,;-6.92,.04,;-5.58,-.73,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530262 (WO2022064009, Compound 39) Show SMILES C[C@@H]1Cc2cnc(N[C@H]3CCOC(C)(C)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530286 (WO2022064009, Compound 156 | WO2022064009, Compoun...) Show SMILES C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530293 (WO2022064009, Compound 54) Show SMILES C[C@H](Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1)c1ccn(C)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	5.13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530298 (WO2022064009, Compound 59) Show SMILES C[C@@H]1Cc2cnc(N[C@H]3CCC[C@H](O)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	5.25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530410 (WO2022064009, Compound 199) Show SMILES CN1CC[C@@H]([C@H](C1)c1ccccc1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2[C@@H]2C[C@H]12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	5.37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530414 (WO2022064009, Compound 203) Show SMILES CN1CC[C@@H]([C@H](C1)c1cccc(C)c1)C(=O)N1Cc2nc(Nc3cnn(C)c3)ncc2[C@@H]2C[C@H]12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	5.37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530312 (WO2022064009, Compound 73) Show SMILES CC(C1CC1)n1cc(Nc2ncc3C[C@@H](C)N(Cc3n2)C(=O)[C@H]2CCN(C)C[C@@H]2c2ccccc2)cn1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	5.75	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM530394 (WO2022064009, Compound 171a) Show SMILES C[C@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022064009	n/a	n/a	5.75	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC936B
					More data for this Ligand-Target Pair

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