Compile Data Set for Download or QSAR

Found 75 hits of ic50 for UniProtKB: P24941   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM513484 (4-(3,3-diethyl-7-fluoro-2-methyl-3H-indol-5-yl)-5-...) Show SMILES CCC1(CC)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc(cn2)C2CCN(C)CC2)ncc1F |c:6| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464620 (CHEMBL4284941 | US11091476, Example 15) Show SMILES CC1=Nc2ccc(cc2C11CCCC1)-c1nc(Nc2ccc(cn2)C2CCNCC2)ncc1F |t:1| Show InChI InChI=1S/C27H29FN6/c1-17-27(10-2-3-11-27)21-14-19(4-6-23(21)32-17)25-22(28)16-31-26(34-25)33-24-7-5-20(15-30-24)18-8-12-29-13-9-18/h4-7,14-16,18,29H,2-3,8-13H2,1H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM513485 (1-(2-((4-(3-Ethyl-7-fluoro-2,3-dimethyl-3H-indol-5...) Show SMILES CCC1(C)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc3CN(CCc3n2)C(=O)CO)ncc1F |c:5| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464612 (CHEMBL4279791 | US11091476, Example 23) Show SMILES CN1CCC(CC1)c1ccc(Nc2ncc(F)c(n2)-c2ccc3N=C(C)C4(CCCC4)c3c2)nc1 |t:25| Show InChI InChI=1S/C28H31FN6/c1-18-28(11-3-4-12-28)22-15-20(5-7-24(22)32-18)26-23(29)17-31-27(34-26)33-25-8-6-21(16-30-25)19-9-13-35(2)14-10-19/h5-8,15-17,19H,3-4,9-14H2,1-2H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50.3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464610 (CHEMBL4279275 | US11091476, Example 35) Show SMILES CCC1(C)C(C)=Nc2ccc(cc12)-c1nc(Nc2ccc(cn2)C2CCN(C)CC2)ncc1F |c:5| Show InChI InChI=1S/C27H31FN6/c1-5-27(3)17(2)31-23-8-6-19(14-21(23)27)25-22(28)16-30-26(33-25)32-24-9-7-20(15-29-24)18-10-12-34(4)13-11-18/h6-9,14-16,18H,5,10-13H2,1-4H3,(H,29,30,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464608 (CHEMBL4278904 | US11091476, Example 19) Show SMILES CCN1CCN(CC1)c1ccc(Nc2ncc(F)c(n2)-c2cc3c(N=C(C)C3(C)CC)c(F)c2)nc1 |t:26| Show InChI InChI=1S/C27H31F2N7/c1-5-27(4)17(3)32-25-20(27)13-18(14-21(25)28)24-22(29)16-31-26(34-24)33-23-8-7-19(15-30-23)36-11-9-35(6-2)10-12-36/h7-8,13-16H,5-6,9-12H2,1-4H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	64.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM513483 (5-Fluoro-N-(5-(1-methylpiperidin-4-yl)pyridin-2-yl...) Show SMILES CN1CCC(CC1)c1ccc(Nc2ncc(F)c(n2)-c2ccc3N=C(C)C(C)(C)c3c2)nc1 |t:25| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	73.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464628 (CHEMBL4284301 | US11091476, Example 24) Show SMILES CCC1(C)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc(cn2)C2CCN(C)CC2)ncc1F |c:5| Show InChI InChI=1S/C27H30F2N6/c1-5-27(3)16(2)32-25-20(27)12-19(13-21(25)28)24-22(29)15-31-26(34-24)33-23-7-6-18(14-30-23)17-8-10-35(4)11-9-17/h6-7,12-15,17H,5,8-11H2,1-4H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	76.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464628 (CHEMBL4284301 | US11091476, Example 24) Show SMILES CCC1(C)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc(cn2)C2CCN(C)CC2)ncc1F |c:5| Show InChI InChI=1S/C27H30F2N6/c1-5-27(3)16(2)32-25-20(27)12-19(13-21(25)28)24-22(29)15-31-26(34-24)33-23-7-6-18(14-30-23)17-8-10-35(4)11-9-17/h6-7,12-15,17H,5,8-11H2,1-4H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	76.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464628 (CHEMBL4284301 | US11091476, Example 24) Show SMILES CCC1(C)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc(cn2)C2CCN(C)CC2)ncc1F |c:5| Show InChI InChI=1S/C27H30F2N6/c1-5-27(3)16(2)32-25-20(27)12-19(13-21(25)28)24-22(29)15-31-26(34-24)33-23-7-6-18(14-30-23)17-8-10-35(4)11-9-17/h6-7,12-15,17H,5,8-11H2,1-4H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	76.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464631 (CHEMBL4288327 | US11091476, Example 29) Show SMILES CCC1(CC)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc(cn2)N2CCNCC2)ncc1F |c:6| Show InChI InChI=1S/C26H29F2N7/c1-4-26(5-2)16(3)32-24-19(26)12-17(13-20(24)27)23-21(28)15-31-25(34-23)33-22-7-6-18(14-30-22)35-10-8-29-9-11-35/h6-7,12-15,29H,4-5,8-11H2,1-3H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	82.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464622 (CHEMBL4280423 | US11091476, Example 7) Show SMILES CCC1(C)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc(cn2)N2CCNCC2)ncc1F |c:5| Show InChI InChI=1S/C25H27F2N7/c1-4-25(3)15(2)31-23-18(25)11-16(12-19(23)26)22-20(27)14-30-24(33-22)32-21-6-5-17(13-29-21)34-9-7-28-8-10-34/h5-6,11-14,28H,4,7-10H2,1-3H3,(H,29,30,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	83.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464622 (CHEMBL4280423 | US11091476, Example 7) Show SMILES CCC1(C)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc(cn2)N2CCNCC2)ncc1F |c:5| Show InChI InChI=1S/C25H27F2N7/c1-4-25(3)15(2)31-23-18(25)11-16(12-19(23)26)22-20(27)14-30-24(33-22)32-21-6-5-17(13-29-21)34-9-7-28-8-10-34/h5-6,11-14,28H,4,7-10H2,1-3H3,(H,29,30,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	83.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464622 (CHEMBL4280423 | US11091476, Example 7) Show SMILES CCC1(C)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc(cn2)N2CCNCC2)ncc1F |c:5| Show InChI InChI=1S/C25H27F2N7/c1-4-25(3)15(2)31-23-18(25)11-16(12-19(23)26)22-20(27)14-30-24(33-22)32-21-6-5-17(13-29-21)34-9-7-28-8-10-34/h5-6,11-14,28H,4,7-10H2,1-3H3,(H,29,30,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	83.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464619 (CHEMBL4292139 | US11091476, Example 16) Show SMILES CCC1(CC)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc(cn2)N2CCN(C)CC2)ncc1F |c:6| Show InChI InChI=1S/C27H31F2N7/c1-5-27(6-2)17(3)32-25-20(27)13-18(14-21(25)28)24-22(29)16-31-26(34-24)33-23-8-7-19(15-30-23)36-11-9-35(4)10-12-36/h7-8,13-16H,5-6,9-12H2,1-4H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	95.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464619 (CHEMBL4292139 | US11091476, Example 16) Show SMILES CCC1(CC)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc(cn2)N2CCN(C)CC2)ncc1F |c:6| Show InChI InChI=1S/C27H31F2N7/c1-5-27(6-2)17(3)32-25-20(27)13-18(14-21(25)28)24-22(29)16-31-26(34-24)33-23-8-7-19(15-30-23)36-11-9-35(4)10-12-36/h7-8,13-16H,5-6,9-12H2,1-4H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	95.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464619 (CHEMBL4292139 | US11091476, Example 16) Show SMILES CCC1(CC)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc(cn2)N2CCN(C)CC2)ncc1F |c:6| Show InChI InChI=1S/C27H31F2N7/c1-5-27(6-2)17(3)32-25-20(27)13-18(14-21(25)28)24-22(29)16-31-26(34-24)33-23-8-7-19(15-30-23)36-11-9-35(4)10-12-36/h7-8,13-16H,5-6,9-12H2,1-4H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	95.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464607 (CHEMBL4293340 | US11091476, Example 36) Show SMILES CCN1CCN(CC1)c1ccc(Nc2ncc(F)c(n2)-c2ccc3N=C(C)C(C)(CC)c3c2)nc1 |t:26| Show InChI InChI=1S/C27H32FN7/c1-5-27(4)18(3)31-23-9-7-19(15-21(23)27)25-22(28)17-30-26(33-25)32-24-10-8-20(16-29-24)35-13-11-34(6-2)12-14-35/h7-10,15-17H,5-6,11-14H2,1-4H3,(H,29,30,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464603 (CHEMBL4291541 | US11091476, Example 11) Show SMILES CCC1(C)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc(cn2)C2CCNCC2)ncc1F |c:5| Show InChI InChI=1S/C26H28F2N6/c1-4-26(3)15(2)32-24-19(26)11-18(12-20(24)27)23-21(28)14-31-25(34-23)33-22-6-5-17(13-30-22)16-7-9-29-10-8-16/h5-6,11-14,16,29H,4,7-10H2,1-3H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464617 (CHEMBL4284737 | US11091476, Example 34) Show SMILES CCC1(C)C(C)=Nc2ccc(cc12)-c1nc(Nc2ccc(cn2)N2CCN(C)CC2)ncc1F |c:5| Show InChI InChI=1S/C26H30FN7/c1-5-26(3)17(2)30-22-8-6-18(14-20(22)26)24-21(27)16-29-25(32-24)31-23-9-7-19(15-28-23)34-12-10-33(4)11-13-34/h6-9,14-16H,5,10-13H2,1-4H3,(H,28,29,31,32)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464629 (CHEMBL4286823 | US11091476, Example 21) Show SMILES CCN1CCC(CC1)c1ccc(Nc2ncc(F)c(n2)-c2ccc3N=C(C)C4(CCCC4)c3c2)nc1 |t:26| Show InChI InChI=1S/C29H33FN6/c1-3-36-14-10-20(11-15-36)22-7-9-26(31-17-22)34-28-32-18-24(30)27(35-28)21-6-8-25-23(16-21)29(19(2)33-25)12-4-5-13-29/h6-9,16-18,20H,3-5,10-15H2,1-2H3,(H,31,32,34,35)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	135	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464626 (CHEMBL4288134 | US11091476, Example 32) Show SMILES CCC1(C)C(C)=Nc2ccc(cc12)-c1nc(Nc2ccc(cn2)N2CCNCC2)ncc1F |c:5| Show InChI InChI=1S/C25H28FN7/c1-4-25(3)16(2)30-21-7-5-17(13-19(21)25)23-20(26)15-29-24(32-23)31-22-8-6-18(14-28-22)33-11-9-27-10-12-33/h5-8,13-15,27H,4,9-12H2,1-3H3,(H,28,29,31,32)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464614 (CHEMBL4277525 | US11091476, Example 6) Show SMILES CC1=Nc2c(cc(cc2F)-c2nc(Nc3ccc(cn3)N3CCNCC3)ncc2F)C11CCCC1 |t:1| Show InChI InChI=1S/C26H27F2N7/c1-16-26(6-2-3-7-26)19-12-17(13-20(27)24(19)32-16)23-21(28)15-31-25(34-23)33-22-5-4-18(14-30-22)35-10-8-29-9-11-35/h4-5,12-15,29H,2-3,6-11H2,1H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464614 (CHEMBL4277525 | US11091476, Example 6) Show SMILES CC1=Nc2c(cc(cc2F)-c2nc(Nc3ccc(cn3)N3CCNCC3)ncc2F)C11CCCC1 |t:1| Show InChI InChI=1S/C26H27F2N7/c1-16-26(6-2-3-7-26)19-12-17(13-20(27)24(19)32-16)23-21(28)15-31-25(34-23)33-22-5-4-18(14-30-22)35-10-8-29-9-11-35/h4-5,12-15,29H,2-3,6-11H2,1H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464614 (CHEMBL4277525 | US11091476, Example 6) Show SMILES CC1=Nc2c(cc(cc2F)-c2nc(Nc3ccc(cn3)N3CCNCC3)ncc2F)C11CCCC1 |t:1| Show InChI InChI=1S/C26H27F2N7/c1-16-26(6-2-3-7-26)19-12-17(13-20(27)24(19)32-16)23-21(28)15-31-25(34-23)33-22-5-4-18(14-30-22)35-10-8-29-9-11-35/h4-5,12-15,29H,2-3,6-11H2,1H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464614 (CHEMBL4277525 | US11091476, Example 6) Show SMILES CC1=Nc2c(cc(cc2F)-c2nc(Nc3ccc(cn3)N3CCNCC3)ncc2F)C11CCCC1 |t:1| Show InChI InChI=1S/C26H27F2N7/c1-16-26(6-2-3-7-26)19-12-17(13-20(27)24(19)32-16)23-21(28)15-31-25(34-23)33-22-5-4-18(14-30-22)35-10-8-29-9-11-35/h4-5,12-15,29H,2-3,6-11H2,1H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM513486 (1-(2-((5-fluoro-4-(7′-fluoro-2′-methyl...) Show SMILES CC1=Nc2c(cc(cc2F)-c2nc(Nc3ccc4CN(CCc4n3)C(=O)CO)ncc2F)C11CCCC1 |t:1| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464638 (CHEMBL4292616 | US11091476, Example 33) Show SMILES CCC1(C)C(C)=Nc2ccc(cc12)-c1nc(Nc2ccc(cn2)C2CCNCC2)ncc1F |c:5| Show InChI InChI=1S/C26H29FN6/c1-4-26(3)16(2)31-22-7-5-18(13-20(22)26)24-21(27)15-30-25(33-24)32-23-8-6-19(14-29-23)17-9-11-28-12-10-17/h5-8,13-15,17,28H,4,9-12H2,1-3H3,(H,29,30,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	166	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464632 (CHEMBL4279832 | US11091476, Example 30) Show SMILES CC1=Nc2c(cc(cc2F)-c2nc(Nc3ccc(cn3)C3CCN(CCO)CC3)ncc2F)C11CCCC1 |t:1| Show InChI InChI=1S/C29H32F2N6O/c1-18-29(8-2-3-9-29)22-14-21(15-23(30)27(22)34-18)26-24(31)17-33-28(36-26)35-25-5-4-20(16-32-25)19-6-10-37(11-7-19)12-13-38/h4-5,14-17,19,38H,2-3,6-13H2,1H3,(H,32,33,35,36)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	177	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464632 (CHEMBL4279832 | US11091476, Example 30) Show SMILES CC1=Nc2c(cc(cc2F)-c2nc(Nc3ccc(cn3)C3CCN(CCO)CC3)ncc2F)C11CCCC1 |t:1| Show InChI InChI=1S/C29H32F2N6O/c1-18-29(8-2-3-9-29)22-14-21(15-23(30)27(22)34-18)26-24(31)17-33-28(36-26)35-25-5-4-20(16-32-25)19-6-10-37(11-7-19)12-13-38/h4-5,14-17,19,38H,2-3,6-13H2,1H3,(H,32,33,35,36)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	177	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464630 (CHEMBL4281514 | US11091476, Example 18) Show SMILES CCC1(C)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc(cn2)N2CCN(C)CC2)ncc1F |c:5| Show InChI InChI=1S/C26H29F2N7/c1-5-26(3)16(2)31-24-19(26)12-17(13-20(24)27)23-21(28)15-30-25(33-23)32-22-7-6-18(14-29-22)35-10-8-34(4)9-11-35/h6-7,12-15H,5,8-11H2,1-4H3,(H,29,30,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464630 (CHEMBL4281514 | US11091476, Example 18) Show SMILES CCC1(C)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc(cn2)N2CCN(C)CC2)ncc1F |c:5| Show InChI InChI=1S/C26H29F2N7/c1-5-26(3)16(2)31-24-19(26)12-17(13-20(24)27)23-21(28)15-30-25(33-23)32-22-7-6-18(14-29-22)35-10-8-34(4)9-11-35/h6-7,12-15H,5,8-11H2,1-4H3,(H,29,30,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464611 (CHEMBL4280895 | US11091476, Example 26) Show SMILES CCN1CCC(CC1)c1ccc(Nc2ncc(F)c(n2)-c2cc3c(N=C(C)C3(C)CC)c(F)c2)nc1 |t:26| Show InChI InChI=1S/C28H32F2N6/c1-5-28(4)17(3)33-26-21(28)13-20(14-22(26)29)25-23(30)16-32-27(35-25)34-24-8-7-19(15-31-24)18-9-11-36(6-2)12-10-18/h7-8,13-16,18H,5-6,9-12H2,1-4H3,(H,31,32,34,35)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	216	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464611 (CHEMBL4280895 | US11091476, Example 26) Show SMILES CCN1CCC(CC1)c1ccc(Nc2ncc(F)c(n2)-c2cc3c(N=C(C)C3(C)CC)c(F)c2)nc1 |t:26| Show InChI InChI=1S/C28H32F2N6/c1-5-28(4)17(3)33-26-21(28)13-20(14-22(26)29)25-23(30)16-32-27(35-25)34-24-8-7-19(15-31-24)18-9-11-36(6-2)12-10-18/h7-8,13-16,18H,5-6,9-12H2,1-4H3,(H,31,32,34,35)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	216	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464621 (CHEMBL4276993 | US11091476, Example 14) Show SMILES CC1=Nc2ccc(cc2C11CCCC1)-c1nc(Nc2ccc(cn2)N2CCNCC2)ncc1F |t:1| Show InChI InChI=1S/C26H28FN7/c1-17-26(8-2-3-9-26)20-14-18(4-6-22(20)31-17)24-21(27)16-30-25(33-24)32-23-7-5-19(15-29-23)34-12-10-28-11-13-34/h4-7,14-16,28H,2-3,8-13H2,1H3,(H,29,30,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	234	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464621 (CHEMBL4276993 | US11091476, Example 14) Show SMILES CC1=Nc2ccc(cc2C11CCCC1)-c1nc(Nc2ccc(cn2)N2CCNCC2)ncc1F |t:1| Show InChI InChI=1S/C26H28FN7/c1-17-26(8-2-3-9-26)20-14-18(4-6-22(20)31-17)24-21(27)16-30-25(33-24)32-23-7-5-19(15-29-23)34-12-10-28-11-13-34/h4-7,14-16,28H,2-3,8-13H2,1H3,(H,29,30,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	234	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464624 (CHEMBL4284768 | US11091476, Example 9) Show SMILES CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3ccc4N=C(C)C5(CCCC5)c4c3)nc2)CC1 |t:24| Show InChI InChI=1S/C29H34FN7/c1-3-36-12-14-37(15-13-36)19-21-6-9-26(31-17-21)34-28-32-18-24(30)27(35-28)22-7-8-25-23(16-22)29(20(2)33-25)10-4-5-11-29/h6-9,16-18H,3-5,10-15,19H2,1-2H3,(H,31,32,34,35)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	268	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464624 (CHEMBL4284768 | US11091476, Example 9) Show SMILES CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3ccc4N=C(C)C5(CCCC5)c4c3)nc2)CC1 |t:24| Show InChI InChI=1S/C29H34FN7/c1-3-36-12-14-37(15-13-36)19-21-6-9-26(31-17-21)34-28-32-18-24(30)27(35-28)22-7-8-25-23(16-22)29(20(2)33-25)10-4-5-11-29/h6-9,16-18H,3-5,10-15,19H2,1-2H3,(H,31,32,34,35)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	268	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464624 (CHEMBL4284768 | US11091476, Example 9) Show SMILES CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3ccc4N=C(C)C5(CCCC5)c4c3)nc2)CC1 |t:24| Show InChI InChI=1S/C29H34FN7/c1-3-36-12-14-37(15-13-36)19-21-6-9-26(31-17-21)34-28-32-18-24(30)27(35-28)22-7-8-25-23(16-22)29(20(2)33-25)10-4-5-11-29/h6-9,16-18H,3-5,10-15,19H2,1-2H3,(H,31,32,34,35)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	268	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM513489 (5-Fluoro-4-(7′-fluoro-2′-methylspiro[c...) Show SMILES CN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc4c(N=C(C)C44CCCC4)c(F)c3)nc2)CC1 |t:23| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	269	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50110183 (Abemaciclib | LY-2835219 | US10626107, Example LY2...) Show SMILES CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc(F)c4nc(C)n(C(C)C)c4c3)nc2)CC1 Show InChI InChI=1S/C27H32F2N8/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	319	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50110183 (Abemaciclib | LY-2835219 | US10626107, Example LY2...) Show SMILES CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc(F)c4nc(C)n(C(C)C)c4c3)nc2)CC1 Show InChI InChI=1S/C27H32F2N8/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	319	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50110183 (Abemaciclib | LY-2835219 | US10626107, Example LY2...) Show SMILES CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc(F)c4nc(C)n(C(C)C)c4c3)nc2)CC1 Show InChI InChI=1S/C27H32F2N8/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	319	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50110183 (Abemaciclib | LY-2835219 | US10626107, Example LY2...) Show SMILES CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc(F)c4nc(C)n(C(C)C)c4c3)nc2)CC1 Show InChI InChI=1S/C27H32F2N8/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	319	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464633 (CHEMBL4285830 | US11091476, Example 13) Show SMILES CC1=Nc2c(cc(cc2F)-c2nc(Nc3ccc(cn3)C3CCNCC3)ncc2F)C11CCCC1 |t:1| Show InChI InChI=1S/C27H28F2N6/c1-16-27(8-2-3-9-27)20-12-19(13-21(28)25(20)33-16)24-22(29)15-32-26(35-24)34-23-5-4-18(14-31-23)17-6-10-30-11-7-17/h4-5,12-15,17,30H,2-3,6-11H2,1H3,(H,31,32,34,35)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	327	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464633 (CHEMBL4285830 | US11091476, Example 13) Show SMILES CC1=Nc2c(cc(cc2F)-c2nc(Nc3ccc(cn3)C3CCNCC3)ncc2F)C11CCCC1 |t:1| Show InChI InChI=1S/C27H28F2N6/c1-16-27(8-2-3-9-27)20-12-19(13-21(28)25(20)33-16)24-22(29)15-32-26(35-24)34-23-5-4-18(14-31-23)17-6-10-30-11-7-17/h4-5,12-15,17,30H,2-3,6-11H2,1H3,(H,31,32,34,35)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	327	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464633 (CHEMBL4285830 | US11091476, Example 13) Show SMILES CC1=Nc2c(cc(cc2F)-c2nc(Nc3ccc(cn3)C3CCNCC3)ncc2F)C11CCCC1 |t:1| Show InChI InChI=1S/C27H28F2N6/c1-16-27(8-2-3-9-27)20-12-19(13-21(28)25(20)33-16)24-22(29)15-32-26(35-24)34-23-5-4-18(14-31-23)17-6-10-30-11-7-17/h4-5,12-15,17,30H,2-3,6-11H2,1H3,(H,31,32,34,35)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	327	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464623 (CHEMBL4287743 | US11091476, Example 28) Show SMILES CC1=Nc2c(cc(cc2F)-c2nc(Nc3ccc(cn3)N3CCN(CCO)CC3)ncc2F)C11CCCC1 |t:1| Show InChI InChI=1S/C28H31F2N7O/c1-18-28(6-2-3-7-28)21-14-19(15-22(29)26(21)33-18)25-23(30)17-32-27(35-25)34-24-5-4-20(16-31-24)37-10-8-36(9-11-37)12-13-38/h4-5,14-17,38H,2-3,6-13H2,1H3,(H,31,32,34,35)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	328	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464623 (CHEMBL4287743 | US11091476, Example 28) Show SMILES CC1=Nc2c(cc(cc2F)-c2nc(Nc3ccc(cn3)N3CCN(CCO)CC3)ncc2F)C11CCCC1 |t:1| Show InChI InChI=1S/C28H31F2N7O/c1-18-28(6-2-3-7-28)21-14-19(15-22(29)26(21)33-18)25-23(30)17-32-27(35-25)34-24-5-4-20(16-31-24)37-10-8-36(9-11-37)12-13-38/h4-5,14-17,38H,2-3,6-13H2,1H3,(H,31,32,34,35)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	328	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM50464618 (CHEMBL4294940 | US11091476, Example 25) Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc(F)c(n2)-c2ccc3N=C(C)C4(CCCC4)c3c2)nc1 |t:25| Show InChI InChI=1S/C27H30FN7/c1-18-27(9-3-4-10-27)21-15-19(5-7-23(21)31-18)25-22(28)17-30-26(33-25)32-24-8-6-20(16-29-24)35-13-11-34(2)12-14-35/h5-8,15-17H,3-4,9-14H2,1-2H3,(H,29,30,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	417	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair

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