Compile Data Set for Download or QSAR

Found 25 hits of ki for UniProtKB: P63138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50165326 (8-Chloro-2-phenyl-5H-3,3a,5,9b-tetraaza-cyclopenta...) Show SMILES Clc1ccc2[nH]c(=O)n3nc(-c4ccccc4)c(=O)n3c2c1 Show InChI InChI=1S/C15H9ClN4O2/c16-10-6-7-11-12(8-10)19-14(21)13(9-4-2-1-3-5-9)18-20(19)15(22)17-11/h1-8H,(H,17,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]-flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha2-beta2-gamma2 expressed in HEK293 cells				J Med Chem 48: 2936-43 (2005) Article DOI: 10.1021/jm0408722 BindingDB Entry DOI: 10.7270/Q2H994QV
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50165325 (2-(4-Methoxy-phenyl)-5H-3,3a,5,9b-tetraaza-cyclope...) Show SMILES COc1ccc(cc1)-c1nn2n(c3ccccc3[nH]c2=O)c1=O Show InChI InChI=1S/C16H12N4O3/c1-23-11-8-6-10(7-9-11)14-15(21)19-13-5-3-2-4-12(13)17-16(22)20(19)18-14/h2-9H,1H3,(H,17,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]-flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha2-beta2-gamma2 expressed in HEK293 cells				J Med Chem 48: 2936-43 (2005) Article DOI: 10.1021/jm0408722 BindingDB Entry DOI: 10.7270/Q2H994QV
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50165329 (8-Chloro-2-(4-methoxy-phenyl)-5H-3,3a,5,9b-tetraaz...) Show SMILES COc1ccc(cc1)-c1nn2n(c3cc(Cl)ccc3[nH]c2=O)c1=O Show InChI InChI=1S/C16H11ClN4O3/c1-24-11-5-2-9(3-6-11)14-15(22)20-13-8-10(17)4-7-12(13)18-16(23)21(20)19-14/h2-8H,1H3,(H,18,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]-flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha2-beta2-gamma2 expressed in HEK293 cells				J Med Chem 48: 2936-43 (2005) Article DOI: 10.1021/jm0408722 BindingDB Entry DOI: 10.7270/Q2H994QV
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50000766 (CHEMBL12 | DIAZEPAM | US9271961, Diazepam) Show SMILES CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |c:10| Show InChI InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50165328 (2-Phenyl-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphth...) Show SMILES O=c1c(nn2n1c1ccccc1[nH]c2=O)-c1ccccc1 Show InChI InChI=1S/C15H10N4O2/c20-14-13(10-6-2-1-3-7-10)17-19-15(21)16-11-8-4-5-9-12(11)18(14)19/h1-9H,(H,16,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]-flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha2-beta2-gamma2 expressed in HEK293 cells				J Med Chem 48: 2936-43 (2005) Article DOI: 10.1021/jm0408722 BindingDB Entry DOI: 10.7270/Q2H994QV
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50206941 (CHEMBL376508 | N-(4-bromobenzyl)-2-(1H-indol-3-yl)...) Show SMILES Brc1ccc(CNC(=O)C(=O)c2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C17H13BrN2O2/c18-12-7-5-11(6-8-12)9-20-17(22)16(21)14-10-19-15-4-2-1-3-13(14)15/h1-8,10,19H,9H2,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABAA alpha2beta2gamma2 expressed in HEK293 cells				J Med Chem 50: 1627-34 (2007) Article DOI: 10.1021/jm0607707 BindingDB Entry DOI: 10.7270/Q2K9376Q
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50185264 (CHEMBL204841 | N-((1H-pyrrol-3-yl)methyl)-2-(5-nit...) Show SMILES [O-][N+](=O)c1ccc2[nH]cc(C(=O)C(=O)NCc3cc[nH]c3)c2c1 Show InChI InChI=1S/C15H12N4O4/c20-14(15(21)18-7-9-3-4-16-6-9)12-8-17-13-2-1-10(19(22)23)5-11(12)13/h1-6,8,16-17H,7H2,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	154	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABA-Aalpha2 receptor plus beta-2-gamma-2 in HEK293 cells				J Med Chem 49: 2489-95 (2006) Article DOI: 10.1021/jm0511841 BindingDB Entry DOI: 10.7270/Q25B038F
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50370710 (CHEMBL1162923) Show SMILES [O-][N+](=O)c1ccc2[nH]cc(C(=O)C(=O)NCc3ccco3)c2c1 Show InChI InChI=1S/C15H11N3O5/c19-14(15(20)17-7-10-2-1-5-23-10)12-8-16-13-4-3-9(18(21)22)6-11(12)13/h1-6,8,16H,7H2,(H,17,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	155	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABA-Aalpha2 receptor plus beta-2-gamma-2 in HEK293 cells				J Med Chem 49: 2489-95 (2006) Article DOI: 10.1021/jm0511841 BindingDB Entry DOI: 10.7270/Q25B038F
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM26266 (Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...) Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1 Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50206936 (CHEMBL375367 | N-isopropyl-2-(5-nitro-1H-indol-3-y...) Show SMILES CC(C)NC(=O)C(=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C13H13N3O4/c1-7(2)15-13(18)12(17)10-6-14-11-4-3-8(16(19)20)5-9(10)11/h3-7,14H,1-2H3,(H,15,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	175	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABAA alpha2beta2gamma2 expressed in HEK293 cells				J Med Chem 50: 1627-34 (2007) Article DOI: 10.1021/jm0607707 BindingDB Entry DOI: 10.7270/Q2K9376Q
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122841 (3-(3H-1lambda*4*-Thiophen-3-yl)-6-thiophen-3-yl-4H...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1ccsc1)-c1ccsc1 Show InChI InChI=1S/C14H9N3OS2/c18-14-12(10-2-4-20-8-10)5-15-13-11(6-16-17(13)14)9-1-3-19-7-9/h1-8,16H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50185269 (CHEMBL203629 | N-(furan-3-ylmethyl)-2-(5-nitro-1H-...) Show SMILES [O-][N+](=O)c1ccc2[nH]cc(C(=O)C(=O)NCc3ccoc3)c2c1 Show InChI InChI=1S/C15H11N3O5/c19-14(15(20)17-6-9-3-4-23-8-9)12-7-16-13-2-1-10(18(21)22)5-11(12)13/h1-5,7-8,16H,6H2,(H,17,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	236	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABA-Aalpha2 receptor plus beta-2-gamma-2 in HEK293 cells				J Med Chem 49: 2489-95 (2006) Article DOI: 10.1021/jm0511841 BindingDB Entry DOI: 10.7270/Q25B038F
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122840 (3-(3-Bromo-phenyl)-6-thiophen-3-yl-4H-pyrazolo[1,5...) Show SMILES Brc1cccc(c1)-c1c[nH]n2c1ncc(-c1ccsc1)c2=O Show InChI InChI=1S/C16H10BrN3OS/c17-12-3-1-2-10(6-12)13-8-19-20-15(13)18-7-14(16(20)21)11-4-5-22-9-11/h1-9,19H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	291	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122847 (3-Pyridin-3-yl-6-thiophen-3-yl-4H-pyrazolo[1,5-a]p...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1cccnc1)-c1ccsc1 Show InChI InChI=1S/C15H10N4OS/c20-15-13(11-3-5-21-9-11)7-17-14-12(8-18-19(14)15)10-2-1-4-16-6-10/h1-9,18H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	315	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50206937 (CHEMBL373871 | N-(4-ethynylbenzyl)-2-(1H-indol-3-y...) Show SMILES O=C(NCc1ccc(cc1)C#C)C(=O)c1c[nH]c2ccccc12 Show InChI InChI=1S/C19H14N2O2/c1-2-13-7-9-14(10-8-13)11-21-19(23)18(22)16-12-20-17-6-4-3-5-15(16)17/h1,3-10,12,20H,11H2,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	414	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABAA alpha2beta2gamma2 expressed in HEK293 cells				J Med Chem 50: 1627-34 (2007) Article DOI: 10.1021/jm0607707 BindingDB Entry DOI: 10.7270/Q2K9376Q
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122843 (6-Thiophen-3-yl-3-(3-trifluoromethyl-phenyl)-4H-py...) Show SMILES FC(F)(F)c1cccc(c1)-c1c[nH]n2c1ncc(-c1ccsc1)c2=O Show InChI InChI=1S/C17H10F3N3OS/c18-17(19,20)12-3-1-2-10(6-12)13-8-22-23-15(13)21-7-14(16(23)24)11-4-5-25-9-11/h1-9,22H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50206938 (CHEMBL222316 | N-butyl-2-(5-nitro-1H-indol-3-yl)-2...) Show SMILES CCCCNC(=O)C(=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C14H15N3O4/c1-2-3-6-15-14(19)13(18)11-8-16-12-5-4-9(17(20)21)7-10(11)12/h4-5,7-8,16H,2-3,6H2,1H3,(H,15,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	553	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABAA alpha2beta2gamma2 expressed in HEK293 cells				J Med Chem 50: 1627-34 (2007) Article DOI: 10.1021/jm0607707 BindingDB Entry DOI: 10.7270/Q2K9376Q
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50185273 (CHEMBL383656 | N-((1H-pyrrol-2-yl)methyl)-2-(5-nit...) Show SMILES [O-][N+](=O)c1ccc2[nH]cc(C(=O)C(=O)NCc3ccc[nH]3)c2c1 Show InChI InChI=1S/C15H12N4O4/c20-14(15(21)18-7-9-2-1-5-16-9)12-8-17-13-4-3-10(19(22)23)6-11(12)13/h1-6,8,16-17H,7H2,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	585	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABA-Aalpha2 receptor plus beta-2-gamma-2 in HEK293 cells				J Med Chem 49: 2489-95 (2006) Article DOI: 10.1021/jm0511841 BindingDB Entry DOI: 10.7270/Q25B038F
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM26266 (Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...) Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1 Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	765	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]-flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha2-beta2-gamma2 expressed in HEK293 cells				J Med Chem 48: 2936-43 (2005) Article DOI: 10.1021/jm0408722 BindingDB Entry DOI: 10.7270/Q2H994QV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM26266 (Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...) Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1 Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	765	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABAA alpha2beta2gamma2 expressed in HEK293 cells				J Med Chem 50: 1627-34 (2007) Article DOI: 10.1021/jm0607707 BindingDB Entry DOI: 10.7270/Q2K9376Q
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM26266 (Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...) Show SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1 Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	765	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABA-Aalpha2 receptor plus beta-2-gamma-2 in HEK293 cells				J Med Chem 49: 2489-95 (2006) Article DOI: 10.1021/jm0511841 BindingDB Entry DOI: 10.7270/Q25B038F
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122845 (3-(3-Methoxy-phenyl)-6-thiophen-3-yl-4H-pyrazolo[1...) Show SMILES COc1cccc(c1)-c1c[nH]n2c1ncc(-c1ccsc1)c2=O Show InChI InChI=1S/C17H13N3O2S/c1-22-13-4-2-3-11(7-13)14-9-19-20-16(14)18-8-15(17(20)21)12-5-6-23-10-12/h2-10,19H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	827	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat alpha2-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122842 (3-Pyridin-2-yl-6-thiophen-3-yl-4H-pyrazolo[1,5-a]p...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1ccccn1)-c1ccsc1 Show InChI InChI=1S/C15H10N4OS/c20-15-11(10-4-6-21-9-10)7-17-14-12(8-18-19(14)15)13-3-1-2-5-16-13/h1-9,18H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	927	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50206942 (CHEMBL385100 | N-(4-ethylbenzyl)-2-(1H-indol-3-yl)...) Show SMILES CCc1ccc(CNC(=O)C(=O)c2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C19H18N2O2/c1-2-13-7-9-14(10-8-13)11-21-19(23)18(22)16-12-20-17-6-4-3-5-15(16)17/h3-10,12,20H,2,11H2,1H3,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABAA alpha2beta2gamma2 expressed in HEK293 cells				J Med Chem 50: 1627-34 (2007) Article DOI: 10.1021/jm0607707 BindingDB Entry DOI: 10.7270/Q2K9376Q
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50122848 (3-Naphthalen-1-yl-6-thiophen-3-yl-4H-pyrazolo[1,5-...) Show SMILES O=c1c(cnc2c(c[nH]n12)-c1cccc2ccccc12)-c1ccsc1 Show InChI InChI=1S/C20H13N3OS/c24-20-17(14-8-9-25-12-14)10-21-19-18(11-22-23(19)20)16-7-3-5-13-4-1-2-6-15(13)16/h1-12,22H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Firenze Curated by ChEMBL					Assay Description Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cells				J Med Chem 46: 310-3 (2003) Article DOI: 10.1021/jm020999w BindingDB Entry DOI: 10.7270/Q2H70F59
					More data for this Ligand-Target Pair