Compile Data Set for Download or QSAR

Found 34 hits of ic50 for UniProtKB: Q14654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118351 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES CC1(CCC1)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:7| Show InChI InChI=1S/C10H12ClN3O2S2/c1-10(3-2-4-10)13-9-12-6-5-7(11)17-8(6)18(15,16)14-9/h5H,2-4H2,1H3,(H2,12,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50012957 (1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfon...) Show SMILES COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1 Show InChI InChI=1S/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human SUR1/Kir6.2 expressed in CHO cells				J Med Chem 44: 1627-53 (2001) BindingDB Entry DOI: 10.7270/Q218376D
					More data for this Ligand-Target Pair				3D Structure (crystal)
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50190500 (6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno...) Show SMILES CC(C)(NC1=Nc2cc(Cl)sc2S(=O)(=O)N1)c1ccccc1 |t:4| Show InChI InChI=1S/C14H14ClN3O2S2/c1-14(2,9-6-4-3-5-7-9)17-13-16-10-8-11(15)21-12(10)22(19,20)18-13/h3-8H,1-2H3,(H2,16,17,18)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells in presence of 2 mM ATP				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118349 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES Clc1cc2N=C(NC3CCC3)NS(=O)(=O)c2s1 |t:4| Show InChI InChI=1S/C9H10ClN3O2S2/c10-7-4-6-8(16-7)17(14,15)13-9(12-6)11-5-2-1-3-5/h4-5H,1-3H2,(H2,11,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118348 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES CCC(C)(C)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:6| Show InChI InChI=1S/C10H14ClN3O2S2/c1-4-10(2,3)13-9-12-6-5-7(11)17-8(6)18(15,16)14-9/h5H,4H2,1-3H3,(H2,12,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118360 (CHEMBL336586 | tert-Butyl-(2-chloro-7,7-dioxo-4,7-...) Show SMILES CC(C)(C)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:5| Show InChI InChI=1S/C9H12ClN3O2S2/c1-9(2,3)12-8-11-5-4-6(10)16-7(5)17(14,15)13-8/h4H,1-3H3,(H2,11,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118359 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7-dithia-4,6-dia...) Show SMILES CC1(CC1)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:6| Show InChI InChI=1S/C9H10ClN3O2S2/c1-9(2-3-9)12-8-11-5-4-6(10)16-7(5)17(14,15)13-8/h4H,2-3H2,1H3,(H2,11,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	286	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells in presence of 2 mM ATP				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118359 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7-dithia-4,6-dia...) Show SMILES CC1(CC1)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:6| Show InChI InChI=1S/C9H10ClN3O2S2/c1-9(2-3-9)12-8-11-5-4-6(10)16-7(5)17(14,15)13-8/h4H,2-3H2,1H3,(H2,11,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118343 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES CC(C)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:4| Show InChI InChI=1S/C8H10ClN3O2S2/c1-4(2)10-8-11-5-3-6(9)15-7(5)16(13,14)12-8/h3-4H,1-2H3,(H2,10,11,12)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50023475 (CHEMBL2111887) Show SMILES CC[C@@H](C)NC1=NS(=O)(=O)c2sc(Cl)cc2N1 |r,t:5| Show InChI InChI=1S/C9H12ClN3O2S2/c1-3-5(2)11-9-12-6-4-7(10)16-8(6)17(14,15)13-9/h4-5H,3H2,1-2H3,(H2,11,12,13)/t5-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118355 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES CCCNC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:4| Show InChI InChI=1S/C8H10ClN3O2S2/c1-2-3-10-8-11-5-4-6(9)15-7(5)16(13,14)12-8/h4H,2-3H2,1H3,(H2,10,11,12)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50099573 (1N-[4-methoxy-3-methylamino(thioxo)methylsulfamoyl...) Show SMILES CNC(=S)NS(=O)(=O)c1cc(CCNC(=O)c2cc(Cl)ccc2OC)ccc1OC Show InChI InChI=1S/C19H22ClN3O5S2/c1-21-19(29)23-30(25,26)17-10-12(4-6-16(17)28-3)8-9-22-18(24)14-11-13(20)5-7-15(14)27-2/h4-7,10-11H,8-9H2,1-3H3,(H,22,24)(H2,21,23,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human SUR1/Kir6.2 expressed in CHO cells				J Med Chem 44: 1627-53 (2001) BindingDB Entry DOI: 10.7270/Q218376D
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118351 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES CC1(CCC1)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:7| Show InChI InChI=1S/C10H12ClN3O2S2/c1-10(3-2-4-10)13-9-12-6-5-7(11)17-8(6)18(15,16)14-9/h5H,2-4H2,1H3,(H2,12,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118349 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES Clc1cc2N=C(NC3CCC3)NS(=O)(=O)c2s1 |t:4| Show InChI InChI=1S/C9H10ClN3O2S2/c10-7-4-6-8(16-7)17(14,15)13-9(12-6)11-5-2-1-3-5/h4-5H,1-3H2,(H2,11,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.46E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118359 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7-dithia-4,6-dia...) Show SMILES CC1(CC1)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:6| Show InChI InChI=1S/C9H10ClN3O2S2/c1-9(2-3-9)12-8-11-5-4-6(10)16-7(5)17(14,15)13-8/h4H,2-3H2,1H3,(H2,11,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.65E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118343 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES CC(C)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:4| Show InChI InChI=1S/C8H10ClN3O2S2/c1-4(2)10-8-11-5-3-6(9)15-7(5)16(13,14)12-8/h3-4H,1-2H3,(H2,10,11,12)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.87E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM86248 (CAS_364-98-7 | NSC_3019 | diazoxide) Show SMILES CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 |t:1| Show InChI InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.94E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells in presence of 2 mM ATP				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM86248 (CAS_364-98-7 | NSC_3019 | diazoxide) Show SMILES CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 |t:1| Show InChI InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	PubMed	n/a	n/a	1.98E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50023475 (CHEMBL2111887) Show SMILES CC[C@@H](C)NC1=NS(=O)(=O)c2sc(Cl)cc2N1 |r,t:5| Show InChI InChI=1S/C9H12ClN3O2S2/c1-3-5(2)11-9-12-6-4-7(10)16-8(6)17(14,15)13-9/h4-5H,3H2,1-2H3,(H2,11,12,13)/t5-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.24E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50190500 (6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno...) Show SMILES CC(C)(NC1=Nc2cc(Cl)sc2S(=O)(=O)N1)c1ccccc1 |t:4| Show InChI InChI=1S/C14H14ClN3O2S2/c1-14(2,9-6-4-3-5-7-9)17-13-16-10-8-11(15)21-12(10)22(19,20)18-13/h3-8H,1-2H3,(H2,16,17,18)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118348 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES CCC(C)(C)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:6| Show InChI InChI=1S/C10H14ClN3O2S2/c1-4-10(2,3)13-9-12-6-5-7(11)17-8(6)18(15,16)14-9/h5H,4H2,1-3H3,(H2,12,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.75E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118360 (CHEMBL336586 | tert-Butyl-(2-chloro-7,7-dioxo-4,7-...) Show SMILES CC(C)(C)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:5| Show InChI InChI=1S/C9H12ClN3O2S2/c1-9(2,3)12-8-11-5-4-6(10)16-7(5)17(14,15)13-8/h4H,1-3H3,(H2,11,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.93E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50023475 (CHEMBL2111887) Show SMILES CC[C@@H](C)NC1=NS(=O)(=O)c2sc(Cl)cc2N1 |r,t:5| Show InChI InChI=1S/C9H12ClN3O2S2/c1-3-5(2)11-9-12-6-4-7(10)16-8(6)17(14,15)13-9/h4-5H,3H2,1-2H3,(H2,11,12,13)/t5-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.87E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118343 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES CC(C)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:4| Show InChI InChI=1S/C8H10ClN3O2S2/c1-4(2)10-8-11-5-3-6(9)15-7(5)16(13,14)12-8/h3-4H,1-2H3,(H2,10,11,12)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.54E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118355 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES CCCNC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:4| Show InChI InChI=1S/C8H10ClN3O2S2/c1-2-3-10-8-11-5-4-6(9)15-7(5)16(13,14)12-8/h4H,2-3H2,1H3,(H2,10,11,12)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.84E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118359 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7-dithia-4,6-dia...) Show SMILES CC1(CC1)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:6| Show InChI InChI=1S/C9H10ClN3O2S2/c1-9(2-3-9)12-8-11-5-4-6(10)16-7(5)17(14,15)13-8/h4H,2-3H2,1H3,(H2,11,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.85E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118359 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7-dithia-4,6-dia...) Show SMILES CC1(CC1)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:6| Show InChI InChI=1S/C9H10ClN3O2S2/c1-9(2-3-9)12-8-11-5-4-6(10)16-7(5)17(14,15)13-8/h4H,2-3H2,1H3,(H2,11,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.96E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM86248 (CAS_364-98-7 | NSC_3019 | diazoxide) Show SMILES CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 |t:1| Show InChI InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	7.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM86248 (CAS_364-98-7 | NSC_3019 | diazoxide) Show SMILES CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 |t:1| Show InChI InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Patents	PubMed	n/a	n/a	7.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118351 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES CC1(CCC1)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:7| Show InChI InChI=1S/C10H12ClN3O2S2/c1-10(3-2-4-10)13-9-12-6-5-7(11)17-8(6)18(15,16)14-9/h5H,2-4H2,1H3,(H2,12,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.59E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118348 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES CCC(C)(C)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:6| Show InChI InChI=1S/C10H14ClN3O2S2/c1-4-10(2,3)13-9-12-6-5-7(11)17-8(6)18(15,16)14-9/h5H,4H2,1-3H3,(H2,12,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.99E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118355 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES CCCNC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:4| Show InChI InChI=1S/C8H10ClN3O2S2/c1-2-3-10-8-11-5-4-6(9)15-7(5)16(13,14)12-8/h4H,2-3H2,1H3,(H2,10,11,12)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.24E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118349 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES Clc1cc2N=C(NC3CCC3)NS(=O)(=O)c2s1 |t:4| Show InChI InChI=1S/C9H10ClN3O2S2/c10-7-4-6-8(16-7)17(14,15)13-9(12-6)11-5-2-1-3-5/h4-5H,1-3H2,(H2,11,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.43E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118360 (CHEMBL336586 | tert-Butyl-(2-chloro-7,7-dioxo-4,7-...) Show SMILES CC(C)(C)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:5| Show InChI InChI=1S/C9H12ClN3O2S2/c1-9(2,3)12-8-11-5-4-6(10)16-7(5)17(14,15)13-8/h4H,1-3H3,(H2,11,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.35E+6	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair