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Compile Data Set for Download or QSAR

Found 26 hits of ec50 for UniProtKB: P34903   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50065229
PNG
(4-Ethyl-6,7-dimethoxy-9H-beta-carboline-3-carboxyl...)
Show SMILES CCc1c([nH]cc2nc3cc(OC)c(OC)cc3c12)C(=O)OC
Show InChI InChI=1S/C17H18N2O4/c1-5-9-15-10-6-13(21-2)14(22-3)7-11(10)19-12(15)8-18-16(9)17(20)23-4/h6-8,18H,5H2,1-4H3
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n/an/an/an/a 10n/an/an/an/a



AstraZeneca Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human alpha3beta3gamma2 GABA receptor expressed in Xenopus laevis oocytes

Bioorg Med Chem 18: 8374-82 (2010)


Article DOI: 10.1016/j.bmc.2010.09.058
BindingDB Entry DOI: 10.7270/Q2FB536X
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50259825
PNG
(CHEMBL4089504)
Show SMILES Fc1ccccc1C1=NCc2c(ncn2-c2ccc(cc12)C#C)-c1cnco1 |t:8|
Show InChI InChI=1S/C22H13FN4O/c1-2-14-7-8-18-16(9-14)21(15-5-3-4-6-17(15)23)25-10-19-22(26-12-27(18)19)20-11-24-13-28-20/h1,3-9,11-13H,10H2
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n/an/an/an/a 11n/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...

J Med Chem 59: 10800-10806 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01332
BindingDB Entry DOI: 10.7270/Q2SQ92T0
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50259822
PNG
(CHEMBL514974)
Show SMILES CCOC(=O)c1ncn-2c1CN=C(c1ccccc1F)c1cc(ccc-21)C#C |t:12|
Show InChI InChI=1S/C22H16FN3O2/c1-3-14-9-10-18-16(11-14)20(15-7-5-6-8-17(15)23)24-12-19-21(22(27)28-4-2)25-13-26(18)19/h1,5-11,13H,4,12H2,2H3
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n/an/an/an/a 29n/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...

J Med Chem 59: 10800-10806 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01332
BindingDB Entry DOI: 10.7270/Q2SQ92T0
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50332374
PNG
(9-Amino-2-cyclobutyl-5-(pyrimidin-2-yl)-2,3-dihydr...)
Show SMILES Nc1c2c(cn(C3CCC3)c2=O)[nH]c2c(cccc12)-c1ncccn1
Show InChI InChI=1S/C19H17N5O/c20-16-12-6-2-7-13(18-21-8-3-9-22-18)17(12)23-14-10-24(11-4-1-5-11)19(25)15(14)16/h2-3,6-11,23H,1,4-5,20H2
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n/an/an/an/a 77n/an/an/an/a



AstraZeneca Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human alpha3beta3gamma2 GABA receptor expressed in Xenopus laevis oocytes

Bioorg Med Chem 18: 8374-82 (2010)


Article DOI: 10.1016/j.bmc.2010.09.058
BindingDB Entry DOI: 10.7270/Q2FB536X
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50000766
PNG
(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Show SMILES CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |c:10|
Show InChI InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3
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n/an/an/an/a 131n/an/an/an/a



AstraZeneca Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human alpha3beta3gamma2 GABA receptor expressed in Xenopus laevis oocytes

Bioorg Med Chem 18: 8374-82 (2010)


Article DOI: 10.1016/j.bmc.2010.09.058
BindingDB Entry DOI: 10.7270/Q2FB536X
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM25883
PNG
(ethyl 12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4...)
Show SMILES CCOC(=O)c1ncn-2c1CN=C(c1ccccc1)c1cc(ccc-21)C#C |t:12|
Show InChI InChI=1S/C22H17N3O2/c1-3-15-10-11-18-17(12-15)20(16-8-6-5-7-9-16)23-13-19-21(22(26)27-4-2)24-14-25(18)19/h1,5-12,14H,4,13H2,2H3
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n/an/an/an/a 146n/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...

J Med Chem 59: 10800-10806 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01332
BindingDB Entry DOI: 10.7270/Q2SQ92T0
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50332375
PNG
(4-Amino-8-(5-(azetidine-1-carbonyl)pyridin-3-yl)-N...)
Show SMILES CCCNC(=O)c1nnc2c(cccc2c1N)-c1cncc(c1)C(=O)N1CCC1
Show InChI InChI=1S/C21H22N6O2/c1-2-7-24-20(28)19-17(22)16-6-3-5-15(18(16)25-26-19)13-10-14(12-23-11-13)21(29)27-8-4-9-27/h3,5-6,10-12H,2,4,7-9H2,1H3,(H2,22,25)(H,24,28)
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n/an/an/an/a 174n/an/an/an/a



AstraZeneca Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human alpha3beta3gamma2 GABA receptor expressed in Xenopus laevis oocytes

Bioorg Med Chem 18: 8374-82 (2010)


Article DOI: 10.1016/j.bmc.2010.09.058
BindingDB Entry DOI: 10.7270/Q2FB536X
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50259814
PNG
(CHEMBL4062225)
Show SMILES C#Cc1ccc-2c(c1)C(=NCc1c(ncn-21)-c1cnco1)c1ccccn1 |c:9|
Show InChI InChI=1S/C21H13N5O/c1-2-14-6-7-17-15(9-14)20(16-5-3-4-8-23-16)24-10-18-21(25-12-26(17)18)19-11-22-13-27-19/h1,3-9,11-13H,10H2
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n/an/an/an/a 205n/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Modulation of recombinant human GABA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as change in GABA-induced current at -80 mV holdin...

J Med Chem 59: 10800-10806 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01332
BindingDB Entry DOI: 10.7270/Q2SQ92T0
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50259815
PNG
(CHEMBL4090978)
Show SMILES C#Cc1ccc-2c(c1)C(=NCc1c(ncn-21)-c1cnco1)c1ccccc1 |c:9|
Show InChI InChI=1S/C22H14N4O/c1-2-15-8-9-18-17(10-15)21(16-6-4-3-5-7-16)24-11-19-22(25-13-26(18)19)20-12-23-14-27-20/h1,3-10,12-14H,11H2
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n/an/an/an/a 321n/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...

J Med Chem 59: 10800-10806 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01332
BindingDB Entry DOI: 10.7270/Q2SQ92T0
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50332376
PNG
(4-Amino-N-propyl-8-(pyrimidin-2-yl)cinnoline-3-car...)
Show SMILES CCCNC(=O)c1nnc2c(cccc2c1N)-c1ncccn1
Show InChI InChI=1S/C16H16N6O/c1-2-7-20-16(23)14-12(17)10-5-3-6-11(13(10)21-22-14)15-18-8-4-9-19-15/h3-6,8-9H,2,7H2,1H3,(H2,17,21)(H,20,23)
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n/an/an/an/a 379n/an/an/an/a



AstraZeneca Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human alpha3beta3gamma2 GABA receptor expressed in Xenopus laevis oocytes

Bioorg Med Chem 18: 8374-82 (2010)


Article DOI: 10.1016/j.bmc.2010.09.058
BindingDB Entry DOI: 10.7270/Q2FB536X
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50259821
PNG
(CHEMBL2332214)
Show SMILES OC(=O)c1ncn-2c1CN=C(c1ccccn1)c1cc(ccc-21)C#C |t:10|
Show InChI InChI=1S/C19H12N4O2/c1-2-12-6-7-15-13(9-12)17(14-5-3-4-8-20-14)21-10-16-18(19(24)25)22-11-23(15)16/h1,3-9,11H,10H2,(H,24,25)
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n/an/an/an/a 470n/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...

J Med Chem 59: 10800-10806 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01332
BindingDB Entry DOI: 10.7270/Q2SQ92T0
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50259824
PNG
(CHEMBL475022)
Show SMILES CCOC(=O)c1ncn-2c1CN=C(c1ccccn1)c1cc(ccc-21)C#C |t:12|
Show InChI InChI=1S/C21H16N4O2/c1-3-14-8-9-17-15(11-14)19(16-7-5-6-10-22-16)23-12-18-20(21(26)27-4-2)24-13-25(17)18/h1,5-11,13H,4,12H2,2H3
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n/an/an/an/a 844n/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...

J Med Chem 59: 10800-10806 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01332
BindingDB Entry DOI: 10.7270/Q2SQ92T0
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50259814
PNG
(CHEMBL4062225)
Show SMILES C#Cc1ccc-2c(c1)C(=NCc1c(ncn-21)-c1cnco1)c1ccccn1 |c:9|
Show InChI InChI=1S/C21H13N5O/c1-2-14-6-7-17-15(9-14)20(16-5-3-4-8-23-16)24-10-18-21(25-12-26(17)18)19-11-22-13-27-19/h1,3-9,11-13H,10H2
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n/an/an/an/a 937n/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...

J Med Chem 59: 10800-10806 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01332
BindingDB Entry DOI: 10.7270/Q2SQ92T0
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM86521
PNG
(CAS_5719 | NSC_5719 | Zaleplon)
Show SMILES CCN(C(C)=O)c1cccc(c1)-c1ccnc2c(cnn12)C#N
Show InChI InChI=1S/C17H15N5O/c1-3-21(12(2)23)15-6-4-5-13(9-15)16-7-8-19-17-14(10-18)11-20-22(16)17/h4-9,11H,3H2,1-2H3
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n/an/an/an/a>1.00E+3n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Modulation of human GABAA alpha3beta3gamma2 expressed in xenopus oocytes assessed as potentiation of GABA-evoked chloride currents

J Med Chem 56: 593-624 (2013)


Article DOI: 10.1021/jm3011433
BindingDB Entry DOI: 10.7270/Q23B61GZ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50259824
PNG
(CHEMBL475022)
Show SMILES CCOC(=O)c1ncn-2c1CN=C(c1ccccn1)c1cc(ccc-21)C#C |t:12|
Show InChI InChI=1S/C21H16N4O2/c1-3-14-8-9-17-15(11-14)19(16-7-5-6-10-22-16)23-12-18-20(21(26)27-4-2)24-13-25(17)18/h1,5-11,13H,4,12H2,2H3
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n/an/an/an/a 1.17E+3n/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...

J Med Chem 59: 10800-10806 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01332
BindingDB Entry DOI: 10.7270/Q2SQ92T0
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50259816
PNG
(CHEMBL4063081)
Show SMILES CCc1noc(n1)-c1ncn-2c1CN=C(c1ccccn1)c1cc(ccc-21)C#C |t:15|
Show InChI InChI=1S/C22H16N6O/c1-3-14-8-9-17-15(11-14)20(16-7-5-6-10-23-16)24-12-18-21(25-13-28(17)18)22-26-19(4-2)27-29-22/h1,5-11,13H,4,12H2,2H3
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n/an/an/an/a 3.02E+3n/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...

J Med Chem 59: 10800-10806 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01332
BindingDB Entry DOI: 10.7270/Q2SQ92T0
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50259820
PNG
(CHEMBL4098713)
Show SMILES Cc1noc(n1)-c1ncn-2c1CN=C(c1ccccn1)c1cc(ccc-21)C#C |t:14|
Show InChI InChI=1S/C21H14N6O/c1-3-14-7-8-17-15(10-14)19(16-6-4-5-9-22-16)23-11-18-20(24-12-27(17)18)21-25-13(2)26-28-21/h1,4-10,12H,11H2,2H3
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n/an/an/an/a 5.15E+3n/an/an/an/a



University of Wisconsin-Milwaukee

Curated by ChEMBL


Assay Description
Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...

J Med Chem 59: 10800-10806 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01332
BindingDB Entry DOI: 10.7270/Q2SQ92T0
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50452383
PNG
(CHEMBL4218339)
Show SMILES CC(C)[C@@H]1N=C(c2ccccc2)c2cc(Cl)ccc2NC1=S |r,t:4|
Show InChI InChI=1S/C18H17ClN2S/c1-11(2)16-18(22)20-15-9-8-13(19)10-14(15)17(21-16)12-6-4-3-5-7-12/h3-11,16H,1-2H3,(H,20,22)/t16-/m0/s1
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n/an/an/an/a>2.40E+4n/an/an/an/a



Roche Pharma Research and Early Development

Curated by ChEMBL


Assay Description
Displacement of [3H]-flumazenil from human GABA-A receptor alpha3beta3gamma2 expressed in HEK293 cells by electrophysiology assay

Bioorg Med Chem Lett 27: 5415-5419 (2017)


Article DOI: 10.1016/j.bmcl.2017.11.008
BindingDB Entry DOI: 10.7270/Q27D2XQ8
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM24183
PNG
(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)
Show SMILES NCCCC(O)=O
Show InChI InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
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n/an/an/an/a 2.80E+4n/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
Effective agonist dose for human Gamma-aminobutyric-acid A receptor alpha6-beta3-gamma2

Bioorg Med Chem Lett 11: 1573-7 (2001)


BindingDB Entry DOI: 10.7270/Q24J0DDQ
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50032955
PNG
(1,2,3,6-Tetrahydro-pyridine-4-carboxylic acid | 1,...)
Show SMILES OC(=O)C1=CCNCC1 |t:3|
Show InChI InChI=1S/C6H9NO2/c8-6(9)5-1-3-7-4-2-5/h1,7H,2-4H2,(H,8,9)
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n/an/an/an/a 5.50E+4n/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
Antagonistic potency against human Gamma-aminobutyric-acid A receptor alpha2-beta3-gamma2 expressed in Xenopus oocytes at 1 mM

Bioorg Med Chem Lett 11: 1573-7 (2001)


BindingDB Entry DOI: 10.7270/Q24J0DDQ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50087272
PNG
(CHEMBL34155 | P4S | Piperidine-4-sulfonic acid | P...)
Show SMILES OS(=O)(=O)C1CCNCC1
Show InChI InChI=1S/C5H11NO3S/c7-10(8,9)5-1-3-6-4-2-5/h5-6H,1-4H2,(H,7,8,9)
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n/an/an/an/a 6.50E+4n/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
Agonist activity on human Gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in Xenopus oocytes

Bioorg Med Chem Lett 11: 1573-7 (2001)


BindingDB Entry DOI: 10.7270/Q24J0DDQ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50100944
PNG
(CHEMBL291079 | Piperidin-4-yl-phosphinic acid)
Show SMILES OP(O)C1=CCNCC1 |t:3|
Show InChI InChI=1S/C5H10NO2P/c7-9(8)5-1-3-6-4-2-5/h1,6-8H,2-4H2
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n/an/an/an/a 1.60E+5n/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
Agonist activity on human Gamma-aminobutyric-acid A receptor alpha2-beta3-gamma2 expressed in Xenopus oocytes

Bioorg Med Chem Lett 11: 1573-7 (2001)


BindingDB Entry DOI: 10.7270/Q24J0DDQ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50100946
PNG
(CHEMBL290961 | Piperidine-4-selenic acid | piperid...)
Show SMILES O[Se](=O)C1CCNCC1
Show InChI InChI=1S/C5H11NO2Se/c7-9(8)5-1-3-6-4-2-5/h5-6H,1-4H2,(H,7,8)
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n/an/an/an/a 1.80E+5n/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
Effective agonist dose for human Gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in Xenopus oocytes

Bioorg Med Chem Lett 11: 1573-7 (2001)


BindingDB Entry DOI: 10.7270/Q24J0DDQ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM85712
PNG
(1H-imidazol-4-ylacetic acid | CAS_645-65-8 | CHEMB...)
Show SMILES OC(=O)Cc1cnc[nH]1
Show InChI InChI=1S/C5H6N2O2/c8-5(9)1-4-2-6-3-7-4/h2-3H,1H2,(H,6,7)(H,8,9)
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n/an/an/an/a 3.00E+5n/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
Antagonistic potency against human Gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in Xenopus oocytes at 1 mM

Bioorg Med Chem Lett 11: 1573-7 (2001)


BindingDB Entry DOI: 10.7270/Q24J0DDQ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50000106
PNG
(4-CARBOXYPIPERIDINE | CHEMBL279998 | Piperidine-4-...)
Show SMILES OC(=O)C1CCNCC1
Show InChI InChI=1S/C6H11NO2/c8-6(9)5-1-3-7-4-2-5/h5,7H,1-4H2,(H,8,9)
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n/an/an/an/a 3.70E+5n/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
Effective agonist dose for human Gamma-aminobutyric-acid A receptor alpha6-beta3-gamma2

Bioorg Med Chem Lett 11: 1573-7 (2001)


BindingDB Entry DOI: 10.7270/Q24J0DDQ
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50100943
PNG
(3-Amino-propane-1-selenic acid | CHEMBL41065)
Show SMILES NCCC[Se](O)=O
Show InChI InChI=1S/C3H9NO2Se/c4-2-1-3-7(5)6/h1-4H2,(H,5,6)
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n/an/an/an/a 4.90E+6n/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
Effective agonist dose for human Gamma-aminobutyric-acid A receptor alpha6-beta3-gamma2

Bioorg Med Chem Lett 11: 1573-7 (2001)


BindingDB Entry DOI: 10.7270/Q24J0DDQ
More data for this
Ligand-Target Pair