Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50509842 (CHEMBL4468229) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce... | ACS Med Chem Lett 10: 248-254 (2019) Article DOI: 10.1021/acsmedchemlett.8b00395 BindingDB Entry DOI: 10.7270/Q2G16441 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50531773 (CHEMBL4475740) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ... | Eur J Med Chem 164: 471-498 (2019) Article DOI: 10.1016/j.ejmech.2018.12.054 BindingDB Entry DOI: 10.7270/Q22J6GB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50509840 (CHEMBL4528294) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce... | ACS Med Chem Lett 10: 248-254 (2019) Article DOI: 10.1021/acsmedchemlett.8b00395 BindingDB Entry DOI: 10.7270/Q2G16441 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50509834 (CHEMBL4583491) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce... | ACS Med Chem Lett 10: 248-254 (2019) Article DOI: 10.1021/acsmedchemlett.8b00395 BindingDB Entry DOI: 10.7270/Q2G16441 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50509841 (CHEMBL4445076) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce... | ACS Med Chem Lett 10: 248-254 (2019) Article DOI: 10.1021/acsmedchemlett.8b00395 BindingDB Entry DOI: 10.7270/Q2G16441 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50531765 (CHEMBL4534780) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ... | Eur J Med Chem 164: 471-498 (2019) Article DOI: 10.1016/j.ejmech.2018.12.054 BindingDB Entry DOI: 10.7270/Q22J6GB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50531766 (CHEMBL4472540) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ... | Eur J Med Chem 164: 471-498 (2019) Article DOI: 10.1016/j.ejmech.2018.12.054 BindingDB Entry DOI: 10.7270/Q22J6GB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50509835 (CHEMBL4443031) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce... | ACS Med Chem Lett 10: 248-254 (2019) Article DOI: 10.1021/acsmedchemlett.8b00395 BindingDB Entry DOI: 10.7270/Q2G16441 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50007024 (CHEMBL3237304) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Inhibition of rat recombinant GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as reduction in current response | J Med Chem 57: 2334-56 (2014) Article DOI: 10.1021/jm401695d BindingDB Entry DOI: 10.7270/Q2SB4786 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50509838 (CHEMBL4440270) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce... | ACS Med Chem Lett 10: 248-254 (2019) Article DOI: 10.1021/acsmedchemlett.8b00395 BindingDB Entry DOI: 10.7270/Q2G16441 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50509844 (CHEMBL4528633) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce... | ACS Med Chem Lett 10: 248-254 (2019) Article DOI: 10.1021/acsmedchemlett.8b00395 BindingDB Entry DOI: 10.7270/Q2G16441 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50531772 (CHEMBL4593032) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ... | Eur J Med Chem 164: 471-498 (2019) Article DOI: 10.1016/j.ejmech.2018.12.054 BindingDB Entry DOI: 10.7270/Q22J6GB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50509843 (CHEMBL4560850) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce... | ACS Med Chem Lett 10: 248-254 (2019) Article DOI: 10.1021/acsmedchemlett.8b00395 BindingDB Entry DOI: 10.7270/Q2G16441 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50509845 (CHEMBL4577751) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce... | ACS Med Chem Lett 10: 248-254 (2019) Article DOI: 10.1021/acsmedchemlett.8b00395 BindingDB Entry DOI: 10.7270/Q2G16441 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50509836 (CHEMBL4553292) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce... | ACS Med Chem Lett 10: 248-254 (2019) Article DOI: 10.1021/acsmedchemlett.8b00395 BindingDB Entry DOI: 10.7270/Q2G16441 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50509846 (CHEMBL4519099) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce... | ACS Med Chem Lett 10: 248-254 (2019) Article DOI: 10.1021/acsmedchemlett.8b00395 BindingDB Entry DOI: 10.7270/Q2G16441 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50509839 (CHEMBL4557334) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce... | ACS Med Chem Lett 10: 248-254 (2019) Article DOI: 10.1021/acsmedchemlett.8b00395 BindingDB Entry DOI: 10.7270/Q2G16441 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50531771 (CHEMBL4438845) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.96E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ... | Eur J Med Chem 164: 471-498 (2019) Article DOI: 10.1016/j.ejmech.2018.12.054 BindingDB Entry DOI: 10.7270/Q22J6GB9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50509837 (CHEMBL4564143) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Negative allosteric modulation of recombinant rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce... | ACS Med Chem Lett 10: 248-254 (2019) Article DOI: 10.1021/acsmedchemlett.8b00395 BindingDB Entry DOI: 10.7270/Q2G16441 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM50246910 (CHEMBL4084540) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Antagonist activity at recombinant rat GluN1a/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-mediated current... | J Med Chem 60: 9885-9904 (2017) Article DOI: 10.1021/acs.jmedchem.7b01624 BindingDB Entry DOI: 10.7270/Q21R6SXD | |||||||||||
More data for this Ligand-Target Pair |