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Compile Data Set for Download or QSAR

Found 48 hits of ic50 for UniProtKB: P08588   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM25764
PNG
(ALPRENOLOL,(+) | ALPRENOLOL,(-) | Alfeprol | Alphe...)
Show SMILES CC(C)NCC(O)COc1ccccc1CC=C
Show InChI InChI=1S/C15H23NO2/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3
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n/an/a 2.30n/an/an/an/an/an/a



Nippon Roche Research Center

Curated by ChEMBL


Assay Description
Compound was evaluated for its Beta adrenergic receptor blocking action

Bioorg Med Chem Lett 11: 1833-7 (2001)


BindingDB Entry DOI: 10.7270/Q2KS6TRW
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM25761
PNG
(Anapriline | Avlocardyl | CHEMBL27 | PROPANOLOL(-)...)
Show SMILES CC(C)NCC(O)COc1cccc2ccccc12
Show InChI InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3
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n/an/a 4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration effective against displacing [3H]dihydroalprenolol from beta adrenergic receptor from canine ventricular tissue

J Med Chem 30: 696-704 (1987)


BindingDB Entry DOI: 10.7270/Q2V1271T
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50218691
PNG
(CHEMBL51667)
Show SMILES CCOC(=O)c1oc2cccc(OCC(O)CNC(C)(C)C)c2c1C
Show InChI InChI=1S/C19H27NO5/c1-6-23-18(22)17-12(2)16-14(8-7-9-15(16)25-17)24-11-13(21)10-20-19(3,4)5/h7-9,13,20-21H,6,10-11H2,1-5H3
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n/an/a 4.30n/an/an/an/an/an/a



Nippon Roche Research Center

Curated by ChEMBL


Assay Description
Compound was evaluated for its Beta adrenergic receptor blocking action

Bioorg Med Chem Lett 11: 1833-7 (2001)


BindingDB Entry DOI: 10.7270/Q2KS6TRW
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM25761
PNG
(Anapriline | Avlocardyl | CHEMBL27 | PROPANOLOL(-)...)
Show SMILES CC(C)NCC(O)COc1cccc2ccccc12
Show InChI InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3
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n/an/a 12n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta Adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50010834
PNG
(1-{2-[4-(3H-Imidazol-1-yl)-phenoxy]-ethylamino}-3-...)
Show SMILES OC(CNCCOc1ccc(cc1)-n1ccnc1)COc1ccccc1
Show InChI InChI=1S/C20H23N3O3/c24-18(15-26-19-4-2-1-3-5-19)14-21-11-13-25-20-8-6-17(7-9-20)23-12-10-22-16-23/h1-10,12,16,18,21,24H,11,13-15H2
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n/an/a 40n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for beta-receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized dogs

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50010840
PNG
(1-{2-[4-(3H-Imidazol-1-yl)-phenoxy]-ethylamino}-3-...)
Show SMILES Cc1cccc(OCC(O)CNCCOc2ccc(cc2)-n2ccnc2)c1
Show InChI InChI=1S/C21H25N3O3/c1-17-3-2-4-21(13-17)27-15-19(25)14-22-10-12-26-20-7-5-18(6-8-20)24-11-9-23-16-24/h2-9,11,13,16,19,22,25H,10,12,14-15H2,1H3
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n/an/a 90n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for beta-receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized dogs

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM96235
PNG
(4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...)
Show SMILES CCOC(=O)c1oc2cccc(OCC(O)CNC(C)C)c2c1C
Show InChI InChI=1S/C18H25NO5/c1-5-22-18(21)17-12(4)16-14(7-6-8-15(16)24-17)23-10-13(20)9-19-11(2)3/h6-8,11,13,19-20H,5,9-10H2,1-4H3
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n/an/a 98n/an/an/an/an/an/a



Nippon Roche Research Center

Curated by ChEMBL


Assay Description
Compound was evaluated for its Beta adrenergic receptor blocking action

Bioorg Med Chem Lett 11: 1833-7 (2001)


BindingDB Entry DOI: 10.7270/Q2KS6TRW
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228546
PNG
(CHEMBL95784)
Show SMILES CS(=O)(=O)Nc1ccc(cc1)C(=O)NCCNCC(O)COc1cccc2ccccc12
Show InChI InChI=1S/C23H27N3O5S/c1-32(29,30)26-19-11-9-18(10-12-19)23(28)25-14-13-24-15-20(27)16-31-22-8-4-6-17-5-2-3-7-21(17)22/h2-12,20,24,26-27H,13-16H2,1H3,(H,25,28)
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n/an/a 150n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50010837
PNG
(1-{2-[4-(3H-Imidazol-1-yl)-phenoxy]-ethylamino}-3-...)
Show SMILES COCCc1ccc(OCC(O)CNCCOc2ccc(cc2)-n2ccnc2)cc1
Show InChI InChI=1S/C23H29N3O4/c1-28-14-10-19-2-6-23(7-3-19)30-17-21(27)16-24-12-15-29-22-8-4-20(5-9-22)26-13-11-25-18-26/h2-9,11,13,18,21,24,27H,10,12,14-17H2,1H3
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n/an/a 270n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for beta-receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized dogs

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228557
PNG
(CHEMBL99718)
Show SMILES OC(CNCCOc1ccc(cc1)-n1ccnc1)CONC(C1CC1)C1CC1
Show InChI InChI=1S/C21H30N4O3/c26-19(14-28-24-21(16-1-2-16)17-3-4-17)13-22-10-12-27-20-7-5-18(6-8-20)25-11-9-23-15-25/h5-9,11,15-17,19,21-22,24,26H,1-4,10,12-14H2
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n/an/a 300n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for beta-receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized dogs

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228540
PNG
(CHEMBL317163)
Show SMILES OC(CNCCNC(=O)c1ccc(cc1)-n1ccnc1)COc1cccc2ccccc12
Show InChI InChI=1S/C25H26N4O3/c30-22(17-32-24-7-3-5-19-4-1-2-6-23(19)24)16-26-12-13-28-25(31)20-8-10-21(11-9-20)29-15-14-27-18-29/h1-11,14-15,18,22,26,30H,12-13,16-17H2,(H,28,31)
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n/an/a 420n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50010841
PNG
(1-(4-Imidazol-1-yl-benzylamino)-3-o-tolyloxy-propa...)
Show SMILES Cc1ccccc1OCC(O)CNCc1ccc(cc1)-n1ccnc1
Show InChI InChI=1S/C20H23N3O2/c1-16-4-2-3-5-20(16)25-14-19(24)13-22-12-17-6-8-18(9-7-17)23-11-10-21-15-23/h2-11,15,19,22,24H,12-14H2,1H3
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n/an/a 780n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50010829
PNG
(CHEMBL95966 | N-{4-[(2-Hydroxy-3-m-tolyloxy-propyl...)
Show SMILES Cc1cccc(OCC(O)CNCc2ccc(NS(C)(=O)=O)cc2)c1
Show InChI InChI=1S/C18H24N2O4S/c1-14-4-3-5-18(10-14)24-13-17(21)12-19-11-15-6-8-16(9-7-15)20-25(2,22)23/h3-10,17,19-21H,11-13H2,1-2H3
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n/an/a 990n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50010842
PNG
(CHEMBL95754 | N-{4-[4-(2-Hydroxy-3-o-tolyloxy-prop...)
Show SMILES Cc1ccccc1OCC(O)CN1CCN(CC1)c1ccc(NS(C)(=O)=O)cc1
Show InChI InChI=1S/C21H29N3O4S/c1-17-5-3-4-6-21(17)28-16-20(25)15-23-11-13-24(14-12-23)19-9-7-18(8-10-19)22-29(2,26)27/h3-10,20,22,25H,11-16H2,1-2H3
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n/an/a 2.30E+3n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228544
PNG
(CHEMBL98979)
Show SMILES CS(=O)(=O)Nc1ccc(cc1)C(=O)NCCNCC(O)COc1ccccc1C#N
Show InChI InChI=1S/C20H24N4O5S/c1-30(27,28)24-17-8-6-15(7-9-17)20(26)23-11-10-22-13-18(25)14-29-19-5-3-2-4-16(19)12-21/h2-9,18,22,24-25H,10-11,13-14H2,1H3,(H,23,26)
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n/an/a 2.90E+3n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228558
PNG
(CHEMBL95911)
Show SMILES CS(=O)(=O)Nc1ccc(CNCC(O)COc2ccccc2)cc1
Show InChI InChI=1S/C17H22N2O4S/c1-24(21,22)19-15-9-7-14(8-10-15)11-18-12-16(20)13-23-17-5-3-2-4-6-17/h2-10,16,18-20H,11-13H2,1H3
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n/an/a 2.90E+3n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50010844
PNG
(CHEMBL316868 | N-[4-(1-Hydroxy-2-{2-[4-(3H-imidazo...)
Show SMILES CS(=O)(=O)Nc1ccc(cc1)C(O)CNCCOc1ccc(cc1)-n1ccnc1
Show InChI InChI=1S/C20H24N4O4S/c1-29(26,27)23-17-4-2-16(3-5-17)20(25)14-21-11-13-28-19-8-6-18(7-9-19)24-12-10-22-15-24/h2-10,12,15,20-21,23,25H,11,13-14H2,1H3
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n/an/a 3.60E+3n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for beta-receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized dogs

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228537
PNG
(CHEMBL320445)
Show SMILES COc1ccccc1C(O)CNCCOc1ccc(cc1)-n1ccnc1
Show InChI InChI=1S/C20H23N3O3/c1-25-20-5-3-2-4-18(20)19(24)14-21-11-13-26-17-8-6-16(7-9-17)23-12-10-22-15-23/h2-10,12,15,19,21,24H,11,13-14H2,1H3
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n/an/a 3.70E+3n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for beta-receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized dogs

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228539
PNG
(CHEMBL318131)
Show SMILES CS(=O)(=O)Nc1ccc(cc1)C(=O)NCCNCC(O)COc1ccccc1
Show InChI InChI=1S/C19H25N3O5S/c1-28(25,26)22-16-9-7-15(8-10-16)19(24)21-12-11-20-13-17(23)14-27-18-5-3-2-4-6-18/h2-10,17,20,22-23H,11-14H2,1H3,(H,21,24)
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n/an/a 3.90E+3n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM25762
PNG
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Show SMILES CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1
Show InChI InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3
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n/an/a 7.20E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration effective against displacing [3H]dihydroalprenolol from beta adrenergic receptor from canine ventricular tissue

J Med Chem 30: 696-704 (1987)


BindingDB Entry DOI: 10.7270/Q2V1271T
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM25762
PNG
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Show SMILES CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1
Show InChI InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3
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n/an/a 7.20E+3n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228542
PNG
(CHEMBL99513)
Show SMILES CS(=O)(=O)Nc1ccc(cc1)N1CCN(CC(O)COc2cccc3C(=O)CCCc23)CC1
Show InChI InChI=1S/C24H31N3O5S/c1-33(30,31)25-18-8-10-19(11-9-18)27-14-12-26(13-15-27)16-20(28)17-32-24-7-3-4-21-22(24)5-2-6-23(21)29/h3-4,7-11,20,25,28H,2,5-6,12-17H2,1H3
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n/an/a 8.40E+3n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50289986
PNG
(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5...)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1C2CC3CN(CC13)C2 |THB:17:16:13:18.19.21,15:16:19:13.14.21|
Show InChI InChI=1S/C16H20ClN3O2/c1-22-14-4-13(18)12(17)3-10(14)16(21)19-15-9-2-8-5-20(6-9)7-11(8)15/h3-4,8-9,11,15H,2,5-7,18H2,1H3,(H,19,21)
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for inhibitory activity against Beta adrenergic receptor

Bioorg Med Chem Lett 7: 2149-2154 (1997)


Article DOI: 10.1016/S0960-894X(97)00408-3
BindingDB Entry DOI: 10.7270/Q27S7NSJ
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50284690
PNG
(1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2-yl)-vinyl]...)
Show SMILES Cc1nc2cnccc2n1-c1ccc(OCc2cccc(\C=C\c3nc4cc(F)ccc4s3)c2)cc1
Show InChI InChI=1S/C29H21FN4OS/c1-19-32-26-17-31-14-13-27(26)34(19)23-7-9-24(10-8-23)35-18-21-4-2-3-20(15-21)5-12-29-33-25-16-22(30)6-11-28(25)36-29/h2-17H,18H2,1H3/b12-5+
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against Beta adrenergic receptor

Bioorg Med Chem Lett 5: 1377-1382 (1995)


Article DOI: 10.1016/0960-894X(95)00227-K
BindingDB Entry DOI: 10.7270/Q2M045D5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50009073
PNG
(4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol...)
Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12)C(=O)NS(=O)(=O)c1ccccc1C
Show InChI InChI=1S/C31H33N3O6S/c1-20-8-4-7-11-29(20)41(37,38)33-30(35)22-13-12-21(28(17-22)39-3)16-23-19-34(2)27-15-14-24(18-26(23)27)32-31(36)40-25-9-5-6-10-25/h4,7-8,11-15,17-19,25H,5-6,9-10,16H2,1-3H3,(H,32,36)(H,33,35)
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against Beta adrenergic receptor

Bioorg Med Chem Lett 5: 1377-1382 (1995)


Article DOI: 10.1016/0960-894X(95)00227-K
BindingDB Entry DOI: 10.7270/Q2M045D5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50284689
PNG
(7-Chloro-2-((E)-2-{3-[4-(2-methyl-imidazo[4,5-c]py...)
Show SMILES Cc1nc2cnccc2n1-c1ccc(OCc2cccc(\C=C\c3ccc4ccc(Cl)cc4n3)c2)cc1
Show InChI InChI=1S/C31H23ClN4O/c1-21-34-30-19-33-16-15-31(30)36(21)27-11-13-28(14-12-27)37-20-23-4-2-3-22(17-23)5-9-26-10-7-24-6-8-25(32)18-29(24)35-26/h2-19H,20H2,1H3/b9-5+
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against Beta adrenergic receptor

Bioorg Med Chem Lett 5: 1377-1382 (1995)


Article DOI: 10.1016/0960-894X(95)00227-K
BindingDB Entry DOI: 10.7270/Q2M045D5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50155152
PNG
(4-Amino-N-(1-aza-tricyclo[3.3.1.1*3,7*]dec-4-yl)-5...)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1C2CC3CC1CN(C3)C2 |TLB:12:13:17:20.19.21,22:20:13.14.15:17,THB:21:20:13:16.15.17,21:16:13:20.19.22,22:14:17:20.19.21,(8.67,-11.69,;8.67,-10.15,;7.33,-9.38,;5.99,-10.15,;4.66,-9.38,;3.32,-10.15,;4.66,-7.83,;3.33,-7.06,;5.99,-7.05,;7.33,-7.82,;8.66,-7.05,;8.66,-5.5,;10.01,-7.81,;11.34,-7.04,;12.54,-5.76,;13.85,-6.25,;15.25,-5.9,;14.24,-7.18,;12.84,-6.62,;12.82,-5.01,;13.87,-3.79,;15.27,-4.37,;12.52,-4.26,)|
Show InChI InChI=1S/C17H22ClN3O2/c1-23-15-5-14(19)13(18)4-12(15)17(22)20-16-10-2-9-3-11(16)8-21(6-9)7-10/h4-5,9-11,16H,2-3,6-8,19H2,1H3,(H,20,22)/t9?,10?,11?,16-
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n/an/a>1.00E+4n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Concentration required for inhibition of beta adrenergic receptor

Bioorg Med Chem Lett 14: 5509-12 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.005
BindingDB Entry DOI: 10.7270/Q2NV9K0K
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50005836
PNG
(4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl...)
Show SMILES COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c1cc(Cl)c(N)cc1OC
Show InChI InChI=1S/C23H29ClFN3O4/c1-30-21-13-19(26)18(24)12-17(21)23(29)27-20-8-10-28(14-22(20)31-2)9-3-11-32-16-6-4-15(25)5-7-16/h4-7,12-13,20,22H,3,8-11,14,26H2,1-2H3,(H,27,29)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Concentration required for inhibition of beta adrenergic receptor

Bioorg Med Chem Lett 14: 5509-12 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.005
BindingDB Entry DOI: 10.7270/Q2NV9K0K
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50181836
PNG
(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5...)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)N[C@@H]1C2CC3CN(CC13)C2 |r,TLB:12:13:16.15:18.19.21,15:14:19:16.17,THB:17:18:13:16.15,17:16:13:18.19.21,12:13:19:16.17,15:16:19:13.14.21|
Show InChI InChI=1S/C16H20ClN3O2/c1-22-14-4-13(18)12(17)3-10(14)16(21)19-15-9-2-8-5-20(6-9)7-11(8)15/h3-4,8-9,11,15H,2,5-7,18H2,1H3,(H,19,21)
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Pfizer Inc.

Curated by ChEMBL


Assay Description
Concentration required for inhibition of beta adrenergic receptor

Bioorg Med Chem Lett 14: 5509-12 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.005
BindingDB Entry DOI: 10.7270/Q2NV9K0K
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50155153
PNG
(4-Amino-N-(1-aza-tricyclo[3.3.1.1*3,7*]dec-4-ylmet...)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NCC1C2CC3CC1CN(C3)C2 |TLB:14:15:19.20.18:22,13:14:20:17.18.22,THB:16:15:20:17.18.22,16:17:15.14.23:20,14:19:15.23.16:22,(-1.58,-4.14,;-1.58,-2.61,;-2.91,-1.83,;-4.24,-2.61,;-5.57,-1.83,;-6.92,-2.61,;-5.57,-.29,;-6.9,.48,;-4.24,.48,;-2.91,-.29,;-1.58,.49,;-1.59,2.04,;-.25,-.26,;1.08,.49,;2.43,-.26,;4.02,.44,;5.42,-.05,;6.33,1.04,;4.81,.48,;3.32,1.02,;3.25,2.53,;4.8,3.07,;6.26,2.56,;4.01,1.86,)|
Show InChI InChI=1S/C18H24ClN3O2/c1-24-17-5-16(20)15(19)4-13(17)18(23)21-6-14-11-2-10-3-12(14)9-22(7-10)8-11/h4-5,10-12,14H,2-3,6-9,20H2,1H3,(H,21,23)/t10?,11?,12?,14-
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n/an/a>1.00E+4n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Concentration required for inhibition of beta adrenergic receptor

Bioorg Med Chem Lett 14: 5509-12 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.005
BindingDB Entry DOI: 10.7270/Q2NV9K0K
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228543
PNG
(CHEMBL99815)
Show SMILES CS(=O)(=O)Nc1ccc(cc1)C(=O)N1CCN(CC(O)COc2ccccc2)CC1
Show InChI InChI=1S/C21H27N3O5S/c1-30(27,28)22-18-9-7-17(8-10-18)21(26)24-13-11-23(12-14-24)15-19(25)16-29-20-5-3-2-4-6-20/h2-10,19,22,25H,11-16H2,1H3
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n/an/a 1.22E+4n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228535
PNG
(CHEMBL99532)
Show SMILES COCCc1ccc(OCC(O)CNCCNC(=O)c2ccc(cc2)-n2ccnc2)cc1
Show InChI InChI=1S/C24H30N4O4/c1-31-15-10-19-2-8-23(9-3-19)32-17-22(29)16-25-11-12-27-24(30)20-4-6-21(7-5-20)28-14-13-26-18-28/h2-9,13-14,18,22,25,29H,10-12,15-17H2,1H3,(H,27,30)
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n/an/a 1.24E+4n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228541
PNG
(CHEMBL317274)
Show SMILES CS(=O)(=O)Nc1ccc(cc1)N1CCN(CC(O)CONC(C2CC2)C2CC2)CC1
Show InChI InChI=1S/C21H34N4O4S/c1-30(27,28)23-18-6-8-19(9-7-18)25-12-10-24(11-13-25)14-20(26)15-29-22-21(16-2-3-16)17-4-5-17/h6-9,16-17,20-23,26H,2-5,10-15H2,1H3
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n/an/a 1.57E+4n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50010828
PNG
(CHEMBL99331 | N-{4-[4-(2-Hydroxy-3-m-tolyloxy-prop...)
Show SMILES Cc1cccc(OCC(O)CN2CCN(CC2)c2ccc(NS(C)(=O)=O)cc2)c1
Show InChI InChI=1S/C21H29N3O4S/c1-17-4-3-5-21(14-17)28-16-20(25)15-23-10-12-24(13-11-23)19-8-6-18(7-9-19)22-29(2,26)27/h3-9,14,20,22,25H,10-13,15-16H2,1-2H3
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n/an/a 1.57E+4n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228536
PNG
(CHEMBL98575)
Show SMILES CS(=O)(=O)Nc1ccc(cc1)N1CCN(CC(O)COc2ccccc2)CC1
Show InChI InChI=1S/C20H27N3O4S/c1-28(25,26)21-17-7-9-18(10-8-17)23-13-11-22(12-14-23)15-19(24)16-27-20-5-3-2-4-6-20/h2-10,19,21,24H,11-16H2,1H3
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n/an/a 1.58E+4n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50101968
PNG
(4-(3-tert-Butylamino-propoxy)-3-methyl-benzofuran-...)
Show SMILES CCOC(=O)c1oc2cccc(OCCCNC(C)(C)C)c2c1C
Show InChI InChI=1S/C19H27NO4/c1-6-22-18(21)17-13(2)16-14(9-7-10-15(16)24-17)23-12-8-11-20-19(3,4)5/h7,9-10,20H,6,8,11-12H2,1-5H3
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n/an/a 2.50E+4n/an/an/an/an/an/a



Nippon Roche Research Center

Curated by ChEMBL


Assay Description
Compound was evaluated for its Beta adrenergic receptor blocking action

Bioorg Med Chem Lett 11: 1833-7 (2001)


BindingDB Entry DOI: 10.7270/Q2KS6TRW
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50010830
PNG
(CHEMBL95727 | N-[4-({2-Hydroxy-3-[4-(2-methoxy-eth...)
Show SMILES COCCc1ccc(OCC(O)CNCc2ccc(NS(C)(=O)=O)cc2)cc1
Show InChI InChI=1S/C20H28N2O5S/c1-26-12-11-16-5-9-20(10-6-16)27-15-19(23)14-21-13-17-3-7-18(8-4-17)22-28(2,24)25/h3-10,19,21-23H,11-15H2,1-2H3
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n/an/a 2.58E+4n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228556
PNG
(CHEMBL99652)
Show SMILES CS(=O)(=O)Nc1ccc(cc1)C(=O)N1CCN(CC(O)COc2cccc3ccccc23)CC1
Show InChI InChI=1S/C25H29N3O5S/c1-34(31,32)26-21-11-9-20(10-12-21)25(30)28-15-13-27(14-16-28)17-22(29)18-33-24-8-4-6-19-5-2-3-7-23(19)24/h2-12,22,26,29H,13-18H2,1H3
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n/an/a 3.09E+4n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50218688
PNG
(CHEMBL416300)
Show SMILES CCOC(=O)c1oc2cccc(OCCCNC(C)C)c2c1C
Show InChI InChI=1S/C18H25NO4/c1-5-21-18(20)17-13(4)16-14(8-6-9-15(16)23-17)22-11-7-10-19-12(2)3/h6,8-9,12,19H,5,7,10-11H2,1-4H3
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n/an/a 3.80E+4n/an/an/an/an/an/a



Nippon Roche Research Center

Curated by ChEMBL


Assay Description
In vitro ability of the compound to displace radiolabelled FTI from farnesyltransferase in cultured Ha-ras transformed RAT1 cells

Bioorg Med Chem Lett 11: 1833-7 (2001)


BindingDB Entry DOI: 10.7270/Q2KS6TRW
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228549
PNG
(CHEMBL95894)
Show SMILES COc1ccc(OCC(O)CNCCNC(=O)c2ccc(NS(C)(=O)=O)cc2)cc1
Show InChI InChI=1S/C20H27N3O6S/c1-28-18-7-9-19(10-8-18)29-14-17(24)13-21-11-12-22-20(25)15-3-5-16(6-4-15)23-30(2,26)27/h3-10,17,21,23-24H,11-14H2,1-2H3,(H,22,25)
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n/an/a 4.38E+4n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228534
PNG
(CHEMBL99188)
Show SMILES COc1ccc(OCC(O)CNCCNC(=O)c2ccc(cc2)-n2ccnc2)cc1
Show InChI InChI=1S/C22H26N4O4/c1-29-20-6-8-21(9-7-20)30-15-19(27)14-23-10-11-25-22(28)17-2-4-18(5-3-17)26-13-12-24-16-26/h2-9,12-13,16,19,23,27H,10-11,14-15H2,1H3,(H,25,28)
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n/an/a 6.14E+4n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228538
PNG
(CHEMBL99391)
Show SMILES COCCc1ccc(OCC(O)CN2CCN(CC2)c2ccc(NS(C)(=O)=O)cc2)cc1
Show InChI InChI=1S/C23H33N3O5S/c1-30-16-11-19-3-9-23(10-4-19)31-18-22(27)17-25-12-14-26(15-13-25)21-7-5-20(6-8-21)24-32(2,28)29/h3-10,22,24,27H,11-18H2,1-2H3
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n/an/a 1.09E+5n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228545
PNG
(CHEMBL99179)
Show SMILES CS(=O)(=O)Nc1ccc(cc1)C(=O)NC1CCCCC1NCC(O)COc1ccccc1
Show InChI InChI=1S/C23H31N3O5S/c1-32(29,30)26-18-13-11-17(12-14-18)23(28)25-22-10-6-5-9-21(22)24-15-19(27)16-31-20-7-3-2-4-8-20/h2-4,7-8,11-14,19,21-22,24,26-27H,5-6,9-10,15-16H2,1H3,(H,25,28)
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n/an/a 1.92E+5n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228548
PNG
(CHEMBL99814)
Show SMILES CS(=O)(=O)Nc1ccc(OCC(O)CNCCNC(=O)c2ccc(cc2)-n2ccnc2)cc1
Show InChI InChI=1S/C22H27N5O5S/c1-33(30,31)26-18-4-8-21(9-5-18)32-15-20(28)14-23-10-11-25-22(29)17-2-6-19(7-3-17)27-13-12-24-16-27/h2-9,12-13,16,20,23,26,28H,10-11,14-15H2,1H3,(H,25,29)
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n/an/a 2.27E+5n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228554
PNG
(CHEMBL95795)
Show SMILES CC(=O)Nc1ccc(OCC(O)CN2CCN(CC2)c2ccc(NS(C)(=O)=O)cc2)cc1
Show InChI InChI=1S/C22H30N4O5S/c1-17(27)23-18-5-9-22(10-6-18)31-16-21(28)15-25-11-13-26(14-12-25)20-7-3-19(4-8-20)24-32(2,29)30/h3-10,21,24,28H,11-16H2,1-2H3,(H,23,27)
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n/an/a 2.93E+5n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228555
PNG
(CHEMBL95985)
Show SMILES COCCc1ccc(OCC(O)CN2CCN(CC2)C(=O)c2ccc(NS(C)(=O)=O)cc2)cc1
Show InChI InChI=1S/C24H33N3O6S/c1-32-16-11-19-3-9-23(10-4-19)33-18-22(28)17-26-12-14-27(15-13-26)24(29)20-5-7-21(8-6-20)25-34(2,30)31/h3-10,22,25,28H,11-18H2,1-2H3
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n/an/a 3.60E+5n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50226751
PNG
(CHEMBL78234)
Show SMILES [Cl-].C[n+]1ccn(CC(O)c2ccc(NS(C)(=O)=O)cc2)c1
Show InChI InChI=1S/C13H18N3O3S.ClH/c1-15-7-8-16(10-15)9-13(17)11-3-5-12(6-4-11)14-20(2,18)19;/h3-8,10,13-14,17H,9H2,1-2H3;1H/q+1;/p-1
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n/an/a 2.35E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory constant of thymidylate synthase was determined in human AML cells

J Med Chem 30: 696-704 (1987)


BindingDB Entry DOI: 10.7270/Q2V1271T
More data for this
Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50228547
PNG
(Sematilide)
Show SMILES CCN(CC)CCNC(=O)c1ccc(NS(C)(=O)=O)cc1
Show InChI InChI=1S/C14H23N3O3S/c1-4-17(5-2)11-10-15-14(18)12-6-8-13(9-7-12)16-21(3,19)20/h6-9,16H,4-5,10-11H2,1-3H3,(H,15,18)
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n/an/a 7.00E+6n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...

J Med Chem 33: 2883-91 (1990)


BindingDB Entry DOI: 10.7270/Q2416XN5
More data for this
Ligand-Target Pair