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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for UniProtKB: P47806   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Zinc finger protein GLI1/GLI2


(Mus musculus)		BDBM50249557
PNG
(2,2'-(2-(pyridin-4-yl)dihydropyrimidine-1,3(2H,4H)...)
Show SMILES CN(C)c1ccccc1CN1CCCN(Cc2ccccc2N(C)C)C1c1ccncc1
Show InChI InChI=1S/C27H35N5/c1-29(2)25-12-7-5-10-23(25)20-31-18-9-19-32(27(31)22-14-16-28-17-15-22)21-24-11-6-8-13-26(24)30(3)4/h5-8,10-17,27H,9,18-21H2,1-4H3
PDB

UniProtKB/SwissProt

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CHEMBL
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Philipps University Marburg

Curated by ChEMBL


Assay Description
Inhibition of GLI1/GLI2 in mouse Shh Light2 cells assessed as reduction in endogenous hedgehog signalling in presence of Smo agonist SAG by luciferas...

J Med Chem 62: 8392-8411 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00188
BindingDB Entry DOI: 10.7270/Q2R214NP
More data for this
Ligand-Target Pair