Compile Data Set for Download or QSAR

Found 697 hits of ic50 for UniProtKB: P29089   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213779 (CHEMBL313598) Show SMILES CCCc1nc(SC)c(C(=O)C[S+]([O-])c2ccccc2)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1cccs1 Show InChI InChI=1S/C34H34N4O5S4/c1-3-10-31-36-33(44-2)32(29(39)23-46(41)27-12-5-4-6-13-27)38(31)22-24-16-18-25(19-17-24)28-14-7-8-15-30(28)47(42,43)37-34(40)35-21-26-11-9-20-45-26/h4-9,11-20H,3,10,21-23H2,1-2H3,(H2,35,37,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.0200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for 50% inhibition of [125I]- AII binding to rat liver membrane preparation (AT1)				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC63CR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213551 (CHEMBL90618) Show SMILES CCCc1nc(SC(F)F)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)CCc1cccs1 Show InChI InChI=1S/C28H27F2N3O5S3/c1-2-6-23-31-26(40-28(29)30)25(27(35)36)33(23)17-18-10-12-19(13-11-18)21-8-3-4-9-22(21)41(37,38)32-24(34)15-14-20-7-5-16-39-20/h3-5,7-13,16,28H,2,6,14-15,17H2,1H3,(H,32,34)(H,35,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars		n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro displacement of [125I]angiotensin II from rat liver (Angiotensin 1 receptor) membrane preparation				Citation and Details BindingDB Entry DOI: 10.7270/Q2S184PR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213695 (CHEMBL89032) Show SMILES CCCCc1nc(SC)c(C(=O)C[S+]([O-])c2ccccc2)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1 Show InChI InChI=1S/C37H38N4O5S3/c1-3-4-19-34-39-36(47-2)35(32(42)26-48(44)30-15-9-6-10-16-30)41(34)25-28-20-22-29(23-21-28)31-17-11-12-18-33(31)49(45,46)40-37(43)38-24-27-13-7-5-8-14-27/h5-18,20-23H,3-4,19,24-26H2,1-2H3,(H2,38,40,43)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for 50% inhibition of [125I]- AII binding to rat liver membrane preparation (AT1)				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC63CR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213592 (CHEMBL315236) Show SMILES CCCCc1nc(SC)c(C(=O)CS(=O)(=O)c2ccccc2)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1 Show InChI InChI=1S/C37H38N4O6S3/c1-3-4-19-34-39-36(48-2)35(32(42)26-49(44,45)30-15-9-6-10-16-30)41(34)25-28-20-22-29(23-21-28)31-17-11-12-18-33(31)50(46,47)40-37(43)38-24-27-13-7-5-8-14-27/h5-18,20-23H,3-4,19,24-26H2,1-2H3,(H2,38,40,43)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for 50% inhibition of [125I]- AII binding to rat liver membrane preparation (AT1)				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC63CR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213685 (CHEMBL431853) Show SMILES CCCCc1nc(SC)c(C(=O)CS(=O)(=O)c2ccc(F)cc2)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1 Show InChI InChI=1S/C37H37FN4O6S3/c1-3-4-14-34-40-36(49-2)35(32(43)25-50(45,46)30-21-19-29(38)20-22-30)42(34)24-27-15-17-28(18-16-27)31-12-8-9-13-33(31)51(47,48)41-37(44)39-23-26-10-6-5-7-11-26/h5-13,15-22H,3-4,14,23-25H2,1-2H3,(H2,39,41,44)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents		n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for 50% inhibition of [125I]- AII binding to rat liver membrane preparation (AT1)				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC63CR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213561 (CHEMBL312937) Show SMILES CCCc1nc(SC(F)F)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)Cc1cccs1 Show InChI InChI=1S/C27H25F2N3O5S3/c1-2-6-22-30-25(39-27(28)29)24(26(34)35)32(22)16-17-10-12-18(13-11-17)20-8-3-4-9-21(20)40(36,37)31-23(33)15-19-7-5-14-38-19/h3-5,7-14,27H,2,6,15-16H2,1H3,(H,31,33)(H,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents		n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro displacement of [125I]angiotensin II from rat liver (Angiotensin 1 receptor) membrane preparation				Citation and Details BindingDB Entry DOI: 10.7270/Q2S184PR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213505 (CHEMBL314975) Show SMILES CCCc1nc(SC(F)F)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)CC1CCCCC1 Show InChI InChI=1S/C29H33F2N3O5S2/c1-2-8-24-32-27(40-29(30)31)26(28(36)37)34(24)18-20-13-15-21(16-14-20)22-11-6-7-12-23(22)41(38,39)33-25(35)17-19-9-4-3-5-10-19/h6-7,11-16,19,29H,2-5,8-10,17-18H2,1H3,(H,33,35)(H,36,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro displacement of [125I]angiotensin II from rat liver (Angiotensin 1 receptor) membrane preparation				Citation and Details BindingDB Entry DOI: 10.7270/Q2S184PR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213687 (CHEMBL87244) Show SMILES CCCc1nc(SC)c(C(=O)C[S+]([O-])c2ccc(C)cc2)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1 Show InChI InChI=1S/C37H38N4O5S3/c1-4-10-34-39-36(47-3)35(32(42)25-48(44)30-21-15-26(2)16-22-30)41(34)24-28-17-19-29(20-18-28)31-13-8-9-14-33(31)49(45,46)40-37(43)38-23-27-11-6-5-7-12-27/h5-9,11-22H,4,10,23-25H2,1-3H3,(H2,38,40,43)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem		n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for 50% inhibition of [125I]- AII binding to rat liver membrane preparation (AT1)				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC63CR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213697 (CHEMBL84908) Show SMILES CCc1nc(SC)c(C(=O)C[S+]([O-])c2ccccc2)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1 Show InChI InChI=1S/C35H34N4O5S3/c1-3-32-37-34(45-2)33(30(40)24-46(42)28-14-8-5-9-15-28)39(32)23-26-18-20-27(21-19-26)29-16-10-11-17-31(29)47(43,44)38-35(41)36-22-25-12-6-4-7-13-25/h4-21H,3,22-24H2,1-2H3,(H2,36,38,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem		n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for 50% inhibition of [125I]- AII binding to rat liver membrane preparation (AT1)				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC63CR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213687 (CHEMBL87244) Show SMILES CCCc1nc(SC)c(C(=O)C[S+]([O-])c2ccc(C)cc2)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1 Show InChI InChI=1S/C37H38N4O5S3/c1-4-10-34-39-36(47-3)35(32(42)25-48(44)30-21-15-26(2)16-22-30)41(34)24-28-17-19-29(20-18-28)31-13-8-9-14-33(31)49(45,46)40-37(43)38-23-27-11-6-5-7-12-27/h5-9,11-22H,4,10,23-25H2,1-3H3,(H2,38,40,43)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem		n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for 50% inhibition of [125I]- AII binding to rat liver membrane preparation (AT1)				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC63CR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213782 (CHEMBL264304) Show SMILES CCCc1nc(SC)c(C(=O)C[S+]([O-])c2ccccc2)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1 Show InChI InChI=1S/C36H36N4O5S3/c1-3-12-33-38-35(46-2)34(31(41)25-47(43)29-15-8-5-9-16-29)40(33)24-27-19-21-28(22-20-27)30-17-10-11-18-32(30)48(44,45)39-36(42)37-23-26-13-6-4-7-14-26/h4-11,13-22H,3,12,23-25H2,1-2H3,(H2,37,39,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for 50% inhibition of [125I]- AII binding to rat liver membrane preparation (AT1)				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC63CR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213688 (CHEMBL86538) Show SMILES CCCc1nc(SC)c(C(C)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1 Show InChI InChI=1S/C30H32N4O4S2/c1-4-10-27-32-29(39-3)28(21(2)35)34(27)20-23-15-17-24(18-16-23)25-13-8-9-14-26(25)40(37,38)33-30(36)31-19-22-11-6-5-7-12-22/h5-9,11-18H,4,10,19-20H2,1-3H3,(H2,31,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for 50% inhibition of [125I]- AII binding to rat liver membrane preparation (AT1)				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC63CR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213593 (CHEMBL91046) Show SMILES CCCCc1nc(SC)c(C(=O)CS(C)(=O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1 Show InChI InChI=1S/C32H36N4O6S3/c1-4-5-15-29-34-31(43-2)30(27(37)22-44(3,39)40)36(29)21-24-16-18-25(19-17-24)26-13-9-10-14-28(26)45(41,42)35-32(38)33-20-23-11-7-6-8-12-23/h6-14,16-19H,4-5,15,20-22H2,1-3H3,(H2,33,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for 50% inhibition of [125I]- AII binding to rat liver membrane preparation (AT1)				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC63CR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50470233 (CHEMBL80177) Show SMILES CCCCc1nc(SC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C30H31N3O5S2/c1-3-4-14-26-31-29(39-2)28(30(35)36)33(26)20-22-15-17-23(18-16-22)24-12-8-9-13-25(24)40(37,38)32-27(34)19-21-10-6-5-7-11-21/h5-13,15-18H,3-4,14,19-20H2,1-2H3,(H,32,34)(H,35,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Roussel PGU Cardiovascular Agents Curated by ChEMBL					Assay Description Specific binding inhibition of [125I]AII to Angiotensin II receptor, type 1 in rat liver membrane				J Med Chem 38: 2357-77 (1995) Article DOI: 10.1021/jm00013a013 BindingDB Entry DOI: 10.7270/Q2KK9FH8
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50470229 (CHEMBL76870) Show SMILES CCCCc1nc(SC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 Show InChI InChI=1S/C29H29N3O5S2/c1-3-4-14-25-30-28(38-2)26(29(34)35)32(25)19-20-15-17-21(18-16-20)23-12-8-9-13-24(23)39(36,37)31-27(33)22-10-6-5-7-11-22/h5-13,15-18H,3-4,14,19H2,1-2H3,(H,31,33)(H,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Roussel PGU Cardiovascular Agents Curated by ChEMBL					Assay Description Specific binding inhibition of [125I]AII to Angiotensin II receptor, type 1 in rat liver membrane				J Med Chem 38: 2357-77 (1995) Article DOI: 10.1021/jm00013a013 BindingDB Entry DOI: 10.7270/Q2KK9FH8
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213681 (CHEMBL433010) Show SMILES CCCc1nc(SC)c(C(=O)CS(=O)(=O)c2ccccc2)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1 Show InChI InChI=1S/C36H36N4O6S3/c1-3-12-33-38-35(47-2)34(31(41)25-48(43,44)29-15-8-5-9-16-29)40(33)24-27-19-21-28(22-20-27)30-17-10-11-18-32(30)49(45,46)39-36(42)37-23-26-13-6-4-7-14-26/h4-11,13-22H,3,12,23-25H2,1-2H3,(H2,37,39,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents		n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for 50% inhibition of [125I]- AII binding to rat liver membrane preparation (AT1)				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC63CR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213680 (CHEMBL87091) Show SMILES CCCCc1nc(SC)c(C(=O)CC(=O)OCC)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1 Show InChI InChI=1S/C34H38N4O6S2/c1-4-6-16-30-36-33(45-3)32(28(39)21-31(40)44-5-2)38(30)23-25-17-19-26(20-18-25)27-14-10-11-15-29(27)46(42,43)37-34(41)35-22-24-12-8-7-9-13-24/h7-15,17-20H,4-6,16,21-23H2,1-3H3,(H2,35,37,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars		n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for 50% inhibition of [125I]- AII binding to rat liver membrane preparation (AT1)				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC63CR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213783 (CHEMBL328985) Show SMILES CCCc1nc(SC)c(C(=O)CS(=O)(=O)c2ccc(OC)cc2)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1 Show InChI InChI=1S/C37H38N4O7S3/c1-4-10-34-39-36(49-3)35(32(42)25-50(44,45)30-21-19-29(48-2)20-22-30)41(34)24-27-15-17-28(18-16-27)31-13-8-9-14-33(31)51(46,47)40-37(43)38-23-26-11-6-5-7-12-26/h5-9,11-22H,4,10,23-25H2,1-3H3,(H2,38,40,43)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for 50% inhibition of [125I]- AII binding to rat liver membrane preparation (AT1)				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC63CR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50470236 (CHEMBL309313) Show SMILES CCCCc1nc(SC)c(C(=O)OCc2ccccc2)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCCC Show InChI InChI=1S/C33H38N4O5S2/c1-4-6-16-29-35-31(43-3)30(32(38)42-23-25-12-8-7-9-13-25)37(29)22-24-17-19-26(20-18-24)27-14-10-11-15-28(27)44(40,41)36-33(39)34-21-5-2/h7-15,17-20H,4-6,16,21-23H2,1-3H3,(H2,34,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Roussel PGU Cardiovascular Agents Curated by ChEMBL					Assay Description Specific binding inhibition of [125I]AII to Angiotensin II receptor, type 1 in rat liver membrane				J Med Chem 38: 2357-77 (1995) Article DOI: 10.1021/jm00013a013 BindingDB Entry DOI: 10.7270/Q2KK9FH8
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50470239 (CHEMBL311312) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nc(SC)c2C(O)=O)cc1 Show InChI InChI=1S/C27H33N3O6S2/c1-4-6-12-23-28-25(37-3)24(26(31)32)30(23)18-19-13-15-20(16-14-19)21-10-8-9-11-22(21)38(34,35)29-27(33)36-17-7-5-2/h8-11,13-16H,4-7,12,17-18H2,1-3H3,(H,29,33)(H,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Roussel PGU Cardiovascular Agents Curated by ChEMBL					Assay Description Specific binding inhibition of [125I]AII to Angiotensin II receptor, type 1 in rat liver membrane				J Med Chem 38: 2357-77 (1995) Article DOI: 10.1021/jm00013a013 BindingDB Entry DOI: 10.7270/Q2KK9FH8
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213504 (CHEMBL89369) Show SMILES CCc1nc(SC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1 Show InChI InChI=1S/C28H28N4O5S2/c1-3-24-30-26(38-2)25(27(33)34)32(24)18-20-13-15-21(16-14-20)22-11-7-8-12-23(22)39(36,37)31-28(35)29-17-19-9-5-4-6-10-19/h4-16H,3,17-18H2,1-2H3,(H,33,34)(H2,29,31,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro displacement of [125I]angiotensin II from rat liver (Angiotensin 1 receptor) membrane preparation				Citation and Details BindingDB Entry DOI: 10.7270/Q2S184PR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213457 (CHEMBL84686) Show SMILES CCCCc1nc(SC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCC1CCCCC1 Show InChI InChI=1S/C30H38N4O5S2/c1-3-4-14-26-32-28(40-2)27(29(35)36)34(26)20-22-15-17-23(18-16-22)24-12-8-9-13-25(24)41(38,39)33-30(37)31-19-21-10-6-5-7-11-21/h8-9,12-13,15-18,21H,3-7,10-11,14,19-20H2,1-2H3,(H,35,36)(H2,31,33,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro displacement of [125I]angiotensin II from rat liver (Angiotensin 1 receptor) membrane preparation				Citation and Details BindingDB Entry DOI: 10.7270/Q2S184PR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213500 (CHEMBL86337) Show SMILES CCCc1nc(SC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1cccs1 Show InChI InChI=1S/C27H28N4O5S3/c1-3-7-23-29-25(37-2)24(26(32)33)31(23)17-18-11-13-19(14-12-18)21-9-4-5-10-22(21)39(35,36)30-27(34)28-16-20-8-6-15-38-20/h4-6,8-15H,3,7,16-17H2,1-2H3,(H,32,33)(H2,28,30,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro displacement of [125I]angiotensin II from rat liver (Angiotensin 1 receptor) membrane preparation				Citation and Details BindingDB Entry DOI: 10.7270/Q2S184PR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213591 (CHEMBL84795) Show SMILES CCCCc1nc(SC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1 Show InChI InChI=1S/C30H32N4O5S2/c1-3-4-14-26-32-28(40-2)27(29(35)36)34(26)20-22-15-17-23(18-16-22)24-12-8-9-13-25(24)41(38,39)33-30(37)31-19-21-10-6-5-7-11-21/h5-13,15-18H,3-4,14,19-20H2,1-2H3,(H,35,36)(H2,31,33,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for 50% inhibition of [125I]- AII binding to rat liver membrane preparation (AT1)				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC63CR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213552 (CHEMBL328302) Show SMILES CCCc1nc(SC(F)F)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)CCc1ccccc1 Show InChI InChI=1S/C30H29F2N3O5S2/c1-2-8-25-33-28(41-30(31)32)27(29(37)38)35(25)19-21-13-16-22(17-14-21)23-11-6-7-12-24(23)42(39,40)34-26(36)18-15-20-9-4-3-5-10-20/h3-7,9-14,16-17,30H,2,8,15,18-19H2,1H3,(H,34,36)(H,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro displacement of [125I]angiotensin II from rat liver (Angiotensin 1 receptor) membrane preparation				Citation and Details BindingDB Entry DOI: 10.7270/Q2S184PR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213567 (CHEMBL315983) Show SMILES CCCc1nc(SC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCC1CCCCC1 Show InChI InChI=1S/C29H36N4O5S2/c1-3-9-25-31-27(39-2)26(28(34)35)33(25)19-21-14-16-22(17-15-21)23-12-7-8-13-24(23)40(37,38)32-29(36)30-18-20-10-5-4-6-11-20/h7-8,12-17,20H,3-6,9-11,18-19H2,1-2H3,(H,34,35)(H2,30,32,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro displacement of [125I]angiotensin II from rat liver (Angiotensin 1 receptor) membrane preparation				Citation and Details BindingDB Entry DOI: 10.7270/Q2S184PR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213460 (CHEMBL85081) Show SMILES CCCc1nc(SC(F)F)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)Cc1ccc2ccccc2c1 Show InChI InChI=1S/C33H29F2N3O5S2/c1-2-7-28-36-31(44-33(34)35)30(32(40)41)38(28)20-21-12-16-24(17-13-21)26-10-5-6-11-27(26)45(42,43)37-29(39)19-22-14-15-23-8-3-4-9-25(23)18-22/h3-6,8-18,33H,2,7,19-20H2,1H3,(H,37,39)(H,40,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro displacement of [125I]angiotensin II from rat liver (Angiotensin 1 receptor) membrane preparation				Citation and Details BindingDB Entry DOI: 10.7270/Q2S184PR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213591 (CHEMBL84795) Show SMILES CCCCc1nc(SC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1 Show InChI InChI=1S/C30H32N4O5S2/c1-3-4-14-26-32-28(40-2)27(29(35)36)34(26)20-22-15-17-23(18-16-22)24-12-8-9-13-25(24)41(38,39)33-30(37)31-19-21-10-6-5-7-11-21/h5-13,15-18H,3-4,14,19-20H2,1-2H3,(H,35,36)(H2,31,33,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro displacement of [125I]angiotensin II from rat liver (Angiotensin 1 receptor) membrane preparation				Citation and Details BindingDB Entry DOI: 10.7270/Q2S184PR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213458 (CHEMBL90672) Show SMILES CCCc1nc(SC(F)F)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)Cc1ccc(F)cc1 Show InChI InChI=1S/C29H26F3N3O5S2/c1-2-5-24-33-27(41-29(31)32)26(28(37)38)35(24)17-19-8-12-20(13-9-19)22-6-3-4-7-23(22)42(39,40)34-25(36)16-18-10-14-21(30)15-11-18/h3-4,6-15,29H,2,5,16-17H2,1H3,(H,34,36)(H,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro displacement of [125I]angiotensin II from rat liver (Angiotensin 1 receptor) membrane preparation				Citation and Details BindingDB Entry DOI: 10.7270/Q2S184PR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213456 (CHEMBL315000) Show SMILES CCCc1nc(SC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCC1CCCC1 Show InChI InChI=1S/C28H34N4O5S2/c1-3-8-24-30-26(38-2)25(27(33)34)32(24)18-20-13-15-21(16-14-20)22-11-6-7-12-23(22)39(36,37)31-28(35)29-17-19-9-4-5-10-19/h6-7,11-16,19H,3-5,8-10,17-18H2,1-2H3,(H,33,34)(H2,29,31,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro displacement of [125I]angiotensin II from rat liver (Angiotensin 1 receptor) membrane preparation				Citation and Details BindingDB Entry DOI: 10.7270/Q2S184PR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50283305 (3'-Fluoro-4'-[6-(3-isopropyl-ureido)-4-oxo-2-propy...) Show SMILES CCCc1nc2ccc(NC(=O)NC(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(CC)cc1F Show InChI InChI=1S/C37H37F2N5O5S/c1-5-9-34-42-32-17-15-26(41-37(47)40-22(3)4)20-29(32)36(46)44(34)21-25-14-13-24(19-30(25)38)27-10-7-8-11-33(27)50(48,49)43-35(45)28-16-12-23(6-2)18-31(28)39/h7-8,10-20,22H,5-6,9,21H2,1-4H3,(H,43,45)(H2,40,41,47)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration against Angiotensin II receptor, type 1 of rat adrenal membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50283317 (2-Propyl-3-(3-fluoro-2'-(3-methylbutyloxycarbonyla...) Show SMILES CCCc1nc2ccc(NC(=O)N3CCOCC3)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C35H40FN5O7S/c1-4-7-32-38-30-13-12-26(37-34(43)40-15-18-47-19-16-40)21-28(30)33(42)41(32)22-25-11-10-24(20-29(25)36)27-8-5-6-9-31(27)49(45,46)39-35(44)48-17-14-23(2)3/h5-6,8-13,20-21,23H,4,7,14-19,22H2,1-3H3,(H,37,43)(H,39,44)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50283300 (2-Butyl-3-(3-fluoro-2'-(3-methylbutyloxycarbonylam...) Show SMILES CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C36H44FN5O6S/c1-7-8-13-33-39-31-17-16-27(38-35(44)41(6)24(4)5)21-29(31)34(43)42(33)22-26-15-14-25(20-30(26)37)28-11-9-10-12-32(28)49(46,47)40-36(45)48-19-18-23(2)3/h9-12,14-17,20-21,23-24H,7-8,13,18-19,22H2,1-6H3,(H,38,44)(H,40,45)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50283310 (4'-[2-Ethyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-...) Show SMILES CCc1ccc(cc1)C(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CC)nc3ccc(NC(=O)N(C)C(C)C)cc3c2=O)c(F)c1 Show InChI InChI=1S/C37H38FN5O5S/c1-6-24-12-14-25(15-13-24)35(44)41-49(47,48)33-11-9-8-10-29(33)26-16-17-27(31(38)20-26)22-43-34(7-2)40-32-19-18-28(21-30(32)36(43)45)39-37(46)42(5)23(3)4/h8-21,23H,6-7,22H2,1-5H3,(H,39,46)(H,41,44)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50283312 (4'-[2-Ethyl-6-(3-isopropyl-ureido)-4-oxo-4H-quinaz...) Show SMILES CCc1ccc(C(=O)NS(=O)(=O)c2ccccc2-c2ccc(Cn3c(CC)nc4ccc(NC(=O)NC(C)C)cc4c3=O)c(F)c2)c(F)c1 Show InChI InChI=1S/C36H35F2N5O5S/c1-5-22-11-15-27(30(38)17-22)34(44)42-49(47,48)32-10-8-7-9-26(32)23-12-13-24(29(37)18-23)20-43-33(6-2)41-31-16-14-25(19-28(31)35(43)45)40-36(46)39-21(3)4/h7-19,21H,5-6,20H2,1-4H3,(H,42,44)(H2,39,40,46)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against AT2 receptor of rat adrenal membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213499 (CHEMBL88653) Show SMILES CCCCc1nc(SC(F)F)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C30H29F2N3O5S2/c1-2-3-13-25-33-28(41-30(31)32)27(29(37)38)35(25)19-21-14-16-22(17-15-21)23-11-7-8-12-24(23)42(39,40)34-26(36)18-20-9-5-4-6-10-20/h4-12,14-17,30H,2-3,13,18-19H2,1H3,(H,34,36)(H,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro displacement of [125I]angiotensin II from rat liver (Angiotensin 1 receptor) membrane preparation				Citation and Details BindingDB Entry DOI: 10.7270/Q2S184PR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50283316 (3'-Fluoro-4'-[6-(3-isopropyl-ureido)-4-oxo-2-propy...) Show SMILES CCCc1nc2ccc(NC(=O)NC(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)COCC(C)C Show InChI InChI=1S/C34H40FN5O6S/c1-6-9-31-38-29-15-14-25(37-34(43)36-22(4)5)17-27(29)33(42)40(31)18-24-13-12-23(16-28(24)35)26-10-7-8-11-30(26)47(44,45)39-32(41)20-46-19-21(2)3/h7-8,10-17,21-22H,6,9,18-20H2,1-5H3,(H,39,41)(H2,36,37,43)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50067536 (5-Hydroxy-2,4-dimethyl-8-[2'-(1H-tetrazol-5-yl)-bi...) Show SMILES Cc1nc(C)c2c(O)cc(=O)n(Cc3ccc(cc3)-c3ccccc3-c3nnn[nH]3)c2n1 Show InChI InChI=1S/C23H19N7O2/c1-13-21-19(31)11-20(32)30(23(21)25-14(2)24-13)12-15-7-9-16(10-8-15)17-5-3-4-6-18(17)22-26-28-29-27-22/h3-11,31H,12H2,1-2H3,(H,26,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Compound was evaluated for the in vitro inhibition of specific binding of [125I]-A II to Angiotensin II receptor, type 1 from rat adrenal membranes.				J Med Chem 41: 4251-60 (1998) Article DOI: 10.1021/jm970690q BindingDB Entry DOI: 10.7270/Q2FB55NK
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50469615 (CHEMBL174546) Show SMILES Cc1cc(C)c2nc(C3CC3)n(C3CCc4cc(ccc34)-c3ccccc3-c3nn[nH]n3)c2n1 Show InChI InChI=1S/C27H25N7/c1-15-13-16(2)28-27-24(15)29-26(17-7-8-17)34(27)23-12-10-19-14-18(9-11-21(19)23)20-5-3-4-6-22(20)25-30-32-33-31-25/h3-6,9,11,13-14,17,23H,7-8,10,12H2,1-2H3,(H,30,31,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against Angiotensin II receptor, type 1 using [125I]Sar-Ile8-AII in rat liver membranes				Citation and Details Article DOI: 10.1016/S0960-894X(01)81128-8 BindingDB Entry DOI: 10.7270/Q2TB19MP
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213781 (CHEMBL327927) Show SMILES CCCCc1nc(SC)c(C(=O)CC(=O)c2ccccc2)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1 Show InChI InChI=1S/C38H38N4O5S2/c1-3-4-19-35-40-37(48-2)36(33(44)24-32(43)30-15-9-6-10-16-30)42(35)26-28-20-22-29(23-21-28)31-17-11-12-18-34(31)49(46,47)41-38(45)39-25-27-13-7-5-8-14-27/h5-18,20-23H,3-4,19,24-26H2,1-2H3,(H2,39,41,45)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for 50% inhibition of [125I]- AII binding to rat liver membrane preparation (AT1)				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC63CR
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50472361 (CHEMBL406349) Show SMILES N[C@H](CC(O)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H]1CCSSCC[C@@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N[C@H](Cc1ccccc1)C(O)=O |wU:59.63,46.47,9.8,31.31,wD:20.19,27.44,63.66,1.0,(-2.49,-6.28,;-2.47,-4.62,;-3.84,-3.93,;-5.11,-4.77,;-5.13,-6.21,;-6.53,-4.07,;-1.11,-3.93,;-1.11,-2.41,;.19,-4.74,;1.56,-4.01,;1.59,-2.47,;2.96,-1.73,;2.99,-.19,;4.35,.53,;4.39,2.07,;5.75,2.8,;3.09,2.89,;2.87,-4.81,;2.68,-3.3,;4.21,-5.54,;5.55,-4.77,;5.54,-3.23,;6.63,-2.13,;7.96,-1.36,;11.63,-.89,;13.17,-.89,;14.26,-1.99,;13.54,-3.36,;12.02,-3.43,;10.48,-3.48,;9.64,-2.18,;9.76,-4.85,;10.66,-6.02,;9.85,-7.26,;10.53,-8.56,;9.71,-9.78,;8.24,-9.71,;7.43,-10.95,;7.57,-8.41,;8.36,-7.17,;8.22,-4.77,;6.89,-5.54,;6.89,-7.08,;14.37,-4.67,;14.36,-6.19,;15.85,-4.25,;17.23,-4.78,;17.41,-6.19,;16.4,-7.33,;15.13,-6.82,;14.1,-7.96,;14.75,-9.19,;16.19,-8.82,;18.23,-3.64,;17.74,-2.18,;19.74,-3.95,;19.74,-2.41,;21.22,-1.94,;22.12,-3.13,;21.21,-4.39,;21.7,-5.86,;20.68,-7.01,;23.2,-6.16,;24.74,-6.17,;25.76,-4.98,;24.97,-3.64,;23.43,-3.64,;22.64,-2.29,;23.43,-.94,;24.97,-.94,;25.76,-2.29,;25.25,-7.63,;24.37,-8.87,;26.67,-7.65,)| Show InChI InChI=1S/C47H63N13O12S2/c48-30(23-38(62)63)39(64)54-31(8-4-16-52-47(49)50)40(65)55-32-14-18-73-74-19-15-33(56-43(68)34(57-41(32)66)20-27-10-12-29(61)13-11-27)42(67)58-35(22-28-24-51-25-53-28)45(70)60-17-5-9-37(60)44(69)59-36(46(71)72)21-26-6-2-1-3-7-26/h1-3,6-7,10-13,24-25,30-37,61H,4-5,8-9,14-23,48H2,(H,51,53)(H,54,64)(H,55,65)(H,56,68)(H,57,66)(H,58,67)(H,59,69)(H,62,63)(H,71,72)(H4,49,50,52)/t30-,31+,32-,33-,34-,35-,36-,37+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro inhibitory activity against rat Angiotensin II receptor, type 1 expressed in CHO cells				J Med Chem 42: 4524-37 (1999) Article DOI: 10.1021/jm991089q BindingDB Entry DOI: 10.7270/Q2PN98C1
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50470206 (CHEMBL445365) Show SMILES CCCCc1nc(SCSC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCCC Show InChI InChI=1S/C27H34N4O5S3/c1-4-6-11-23-29-25(38-18-37-3)24(26(32)33)31(23)17-19-12-14-20(15-13-19)21-9-7-8-10-22(21)39(35,36)30-27(34)28-16-5-2/h7-10,12-15H,4-6,11,16-18H2,1-3H3,(H,32,33)(H2,28,30,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Roussel PGU Cardiovascular Agents Curated by ChEMBL					Assay Description Specific binding inhibition of [125I]AII to Angiotensin II receptor, type 1 in rat liver membrane				J Med Chem 38: 2357-77 (1995) Article DOI: 10.1021/jm00013a013 BindingDB Entry DOI: 10.7270/Q2KK9FH8
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213569 (CHEMBL78866) Show SMILES CCCCNC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nc(SC)c2C(O)=O)cc1 Show InChI InChI=1S/C27H34N4O5S2/c1-4-6-12-23-29-25(37-3)24(26(32)33)31(23)18-19-13-15-20(16-14-19)21-10-8-9-11-22(21)38(35,36)30-27(34)28-17-7-5-2/h8-11,13-16H,4-7,12,17-18H2,1-3H3,(H,32,33)(H2,28,30,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Roussel PGU Cardiovascular Agents Curated by ChEMBL					Assay Description Specific binding inhibition of [125I]AII to Angiotensin II receptor, type 1 in rat liver membrane				J Med Chem 38: 2357-77 (1995) Article DOI: 10.1021/jm00013a013 BindingDB Entry DOI: 10.7270/Q2KK9FH8
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50470225 (CHEMBL80700) Show SMILES CCCCc1nc(SCCCO)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCCC Show InChI InChI=1S/C28H36N4O6S2/c1-3-5-11-24-30-26(39-18-8-17-33)25(27(34)35)32(24)19-20-12-14-21(15-13-20)22-9-6-7-10-23(22)40(37,38)31-28(36)29-16-4-2/h6-7,9-10,12-15,33H,3-5,8,11,16-19H2,1-2H3,(H,34,35)(H2,29,31,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Roussel PGU Cardiovascular Agents Curated by ChEMBL					Assay Description Specific binding inhibition of [125I]AII to Angiotensin II receptor, type 1 in rat liver membrane				J Med Chem 38: 2357-77 (1995) Article DOI: 10.1021/jm00013a013 BindingDB Entry DOI: 10.7270/Q2KK9FH8
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50470226 (CHEMBL311827) Show SMILES CCCCc1nc(Sc2cccs2)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCCC Show InChI InChI=1S/C29H32N4O5S3/c1-3-5-11-24-31-27(40-25-12-8-18-39-25)26(28(34)35)33(24)19-20-13-15-21(16-14-20)22-9-6-7-10-23(22)41(37,38)32-29(36)30-17-4-2/h6-10,12-16,18H,3-5,11,17,19H2,1-2H3,(H,34,35)(H2,30,32,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Roussel PGU Cardiovascular Agents Curated by ChEMBL					Assay Description Specific binding inhibition of [125I]AII to Angiotensin II receptor, type 1 in rat liver membrane				J Med Chem 38: 2357-77 (1995) Article DOI: 10.1021/jm00013a013 BindingDB Entry DOI: 10.7270/Q2KK9FH8
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50470235 (CHEMBL308135) Show SMILES CCCCc1nc(SC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OCC(C)C Show InChI InChI=1S/C27H33N3O6S2/c1-5-6-11-23-28-25(37-4)24(26(31)32)30(23)16-19-12-14-20(15-13-19)21-9-7-8-10-22(21)38(34,35)29-27(33)36-17-18(2)3/h7-10,12-15,18H,5-6,11,16-17H2,1-4H3,(H,29,33)(H,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Roussel PGU Cardiovascular Agents Curated by ChEMBL					Assay Description Specific binding inhibition of [125I]AII to Angiotensin II receptor, type 1 in rat liver membrane				J Med Chem 38: 2357-77 (1995) Article DOI: 10.1021/jm00013a013 BindingDB Entry DOI: 10.7270/Q2KK9FH8
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50031491 (2-propyl-4-(methythio)-1-[[[2'-[(propylamino)carbo...) Show SMILES CCCNC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc(SC)c2C(O)=O)cc1 Show InChI InChI=1S/C25H30N4O5S2/c1-4-8-21-27-23(35-3)22(24(30)31)29(21)16-17-11-13-18(14-12-17)19-9-6-7-10-20(19)36(33,34)28-25(32)26-15-5-2/h6-7,9-14H,4-5,8,15-16H2,1-3H3,(H,30,31)(H2,26,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Roussel PGU Cardiovascular Agents Curated by ChEMBL					Assay Description Specific binding inhibition of [125I]AII to Angiotensin II receptor, type 1 in rat liver membrane				J Med Chem 38: 2357-77 (1995) Article DOI: 10.1021/jm00013a013 BindingDB Entry DOI: 10.7270/Q2KK9FH8
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213557 (CHEMBL309602) Show SMILES CCCCc1nc(SC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCC Show InChI InChI=1S/C25H30N4O5S2/c1-4-6-11-21-27-23(35-3)22(24(30)31)29(21)16-17-12-14-18(15-13-17)19-9-7-8-10-20(19)36(33,34)28-25(32)26-5-2/h7-10,12-15H,4-6,11,16H2,1-3H3,(H,30,31)(H2,26,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Roussel PGU Cardiovascular Agents Curated by ChEMBL					Assay Description Specific binding inhibition of [125I]AII to Angiotensin II receptor, type 1 in rat liver membrane				J Med Chem 38: 2357-77 (1995) Article DOI: 10.1021/jm00013a013 BindingDB Entry DOI: 10.7270/Q2KK9FH8
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50470250 (CHEMBL77308) Show SMILES CCCCc1nc(SC)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)CCC Show InChI InChI=1S/C26H31N3O5S2/c1-4-6-12-22-27-25(35-3)24(26(31)32)29(22)17-18-13-15-19(16-14-18)20-10-7-8-11-21(20)36(33,34)28-23(30)9-5-2/h7-8,10-11,13-16H,4-6,9,12,17H2,1-3H3,(H,28,30)(H,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Roussel PGU Cardiovascular Agents Curated by ChEMBL					Assay Description Specific binding inhibition of [125I]AII to Angiotensin II receptor, type 1 in rat liver membrane				J Med Chem 38: 2357-77 (1995) Article DOI: 10.1021/jm00013a013 BindingDB Entry DOI: 10.7270/Q2KK9FH8
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50213550 (CHEMBL87847) Show SMILES CCCCc1nc(SC(F)F)c(C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)CC1CCCCC1 Show InChI InChI=1S/C30H35F2N3O5S2/c1-2-3-13-25-33-28(41-30(31)32)27(29(37)38)35(25)19-21-14-16-22(17-15-21)23-11-7-8-12-24(23)42(39,40)34-26(36)18-20-9-5-4-6-10-20/h7-8,11-12,14-17,20,30H,2-6,9-10,13,18-19H2,1H3,(H,34,36)(H,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem		n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro displacement of [125I]angiotensin II from rat liver (Angiotensin 1 receptor) membrane preparation				Citation and Details BindingDB Entry DOI: 10.7270/Q2S184PR
					More data for this Ligand-Target Pair

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