Found 424 hits of ic50 for UniProtKB: P35355 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472616
(CHEMBL65325)Show SMILES CN1CC\C(=C\c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C19H29NO3S/c1-18(2,3)15-11-13(12-16(17(15)21)19(4,5)6)10-14-8-9-20(7)24(14,22)23/h10-12,21H,8-9H2,1-7H3/b14-10- | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472627
(CHEMBL304489)Show SMILES CC(C)(C)c1cc(\C=C2\CCN(c3ccc(Cl)cc3)S2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C24H30ClNO3S/c1-23(2,3)20-14-16(15-21(22(20)27)24(4,5)6)13-19-11-12-26(30(19,28)29)18-9-7-17(25)8-10-18/h7-10,13-15,27H,11-12H2,1-6H3/b19-13- | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472632
(CHEMBL65140)Show SMILES CC(=O)N1CC\C(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C20H29NO4S/c1-13(22)21-9-8-15(26(21,24)25)10-14-11-16(19(2,3)4)18(23)17(12-14)20(5,6)7/h10-12,23H,8-9H2,1-7H3/b15-10+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472618
(CHEMBL303092)Show SMILES CON1CC\C(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C19H29NO4S/c1-18(2,3)15-11-13(12-16(17(15)21)19(4,5)6)10-14-8-9-20(24-7)25(14,22)23/h10-12,21H,8-9H2,1-7H3/b14-10+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472623
(CHEMBL294100)Show SMILES CC(C)(C)c1cc(\C=C2\CCNS2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C18H27NO3S/c1-17(2,3)14-10-12(9-13-7-8-19-23(13,21)22)11-15(16(14)20)18(4,5)6/h9-11,19-20H,7-8H2,1-6H3/b13-9- | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472624
(CHEMBL62439)Show SMILES CC(C)(C)c1cc(\C=C2/CCN(c3ccc(Cl)cc3)S2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C24H30ClNO3S/c1-23(2,3)20-14-16(15-21(22(20)27)24(4,5)6)13-19-11-12-26(30(19,28)29)18-9-7-17(25)8-10-18/h7-10,13-15,27H,11-12H2,1-6H3/b19-13+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472613
(CHEMBL305076)Show SMILES CCN1CC\C(=C\c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C20H31NO3S/c1-8-21-10-9-15(25(21,23)24)11-14-12-16(19(2,3)4)18(22)17(13-14)20(5,6)7/h11-13,22H,8-10H2,1-7H3/b15-11- | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472612
(CHEMBL60496)Show SMILES CC(C)(C)c1cc(\C=C2/CCN(C3CC3)S2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C21H31NO3S/c1-20(2,3)17-12-14(13-18(19(17)23)21(4,5)6)11-16-9-10-22(15-7-8-15)26(16,24)25/h11-13,15,23H,7-10H2,1-6H3/b16-11+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472605
(CHEMBL64507)Show SMILES CON1CC\C(=C\c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C19H29NO4S/c1-18(2,3)15-11-13(12-16(17(15)21)19(4,5)6)10-14-8-9-20(24-7)25(14,22)23/h10-12,21H,8-9H2,1-7H3/b14-10- | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM17638
(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472615
(CHEMBL64813)Show SMILES CC(C)(C)c1cc(\C=C2/CCCNS2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C19H29NO3S/c1-18(2,3)15-11-13(12-16(17(15)21)19(4,5)6)10-14-8-7-9-20-24(14,22)23/h10-12,20-21H,7-9H2,1-6H3/b14-10+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472610
(CHEMBL60725)Show SMILES CN1CC\C(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C19H29NO3S/c1-18(2,3)15-11-13(12-16(17(15)21)19(4,5)6)10-14-8-9-20(7)24(14,22)23/h10-12,21H,8-9H2,1-7H3/b14-10+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472622
(CHEMBL291543)Show SMILES CCN1CC\C(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C20H31NO3S/c1-8-21-10-9-15(25(21,23)24)11-14-12-16(19(2,3)4)18(22)17(13-14)20(5,6)7/h11-13,22H,8-10H2,1-7H3/b15-11+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50076661
(CHEMBL177727 | N-{1-Ethyl-3-[1-(4-methoxy-phenyl)-...)Show SMILES CCC(C#Cc1cc(-c2ccc(C)cc2)n(n1)-c1ccc(OC)cc1)N(O)C(C)=O Show InChI InChI=1S/C24H25N3O3/c1-5-21(27(29)18(3)28)11-10-20-16-24(19-8-6-17(2)7-9-19)26(25-20)22-12-14-23(30-4)15-13-22/h6-9,12-16,21,29H,5H2,1-4H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
The R.W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1) |
Bioorg Med Chem Lett 9: 979-84 (1999)
BindingDB Entry DOI: 10.7270/Q2Z31XV3 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50076666
(CHEMBL175153 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...)Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CC(C)N(O)C(C)=O Show InChI InChI=1S/C23H23N3O3/c1-16-5-8-19(9-6-16)23-15-20(10-7-17(2)26(28)18(3)27)24-25(23)21-11-13-22(29-4)14-12-21/h5-6,8-9,11-15,17,28H,1-4H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
The R.W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1) |
Bioorg Med Chem Lett 9: 979-84 (1999)
BindingDB Entry DOI: 10.7270/Q2Z31XV3 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50331888
(5-Chloro-2-oxo-3-(thiophene-2-carbonyl)-2,3-dihydr...)Show InChI InChI=1S/C14H9ClN2O3S/c15-7-3-4-9-8(6-7)11(13(19)17(9)14(16)20)12(18)10-2-1-5-21-10/h1-6,19H,(H2,16,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
| PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research
Curated by ChEMBL
| Assay Description In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cells |
J Med Chem 33: 2019-24 (1990)
BindingDB Entry DOI: 10.7270/Q2G73F9X |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472631
(CHEMBL60738)Show SMILES CC(C)(C)c1cc(\C=C2/CCN(O)S2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C18H27NO4S/c1-17(2,3)14-10-12(11-15(16(14)20)18(4,5)6)9-13-7-8-19(21)24(13,22)23/h9-11,20-21H,7-8H2,1-6H3/b13-9+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50075539
(3-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-[1,2,4]thia...)Show SMILES CC(C)(C)c1cc(cc(c1O)C(C)(C)C)-c1nsc(NC#N)n1 Show InChI InChI=1S/C17H22N4OS/c1-16(2,3)11-7-10(8-12(13(11)22)17(4,5)6)14-20-15(19-9-18)23-21-14/h7-8,22H,1-6H3,(H,19,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Evaluated in vitro for its inhibitory activity against Prostaglandin G/H synthase |
J Med Chem 35: 3691-8 (1992)
BindingDB Entry DOI: 10.7270/Q2M61KWB |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472619
(CHEMBL62990)Show SMILES CCCN1CC\C(=C\c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C21H33NO3S/c1-8-10-22-11-9-16(26(22,24)25)12-15-13-17(20(2,3)4)19(23)18(14-15)21(5,6)7/h12-14,23H,8-11H2,1-7H3/b16-12- | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472625
(CHEMBL62920)Show SMILES CCCN1CC\C(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O Show InChI InChI=1S/C21H33NO3S/c1-8-10-22-11-9-16(26(22,24)25)12-15-13-17(20(2,3)4)19(23)18(14-15)21(5,6)7/h12-14,23H,8-11H2,1-7H3/b16-12+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50012860
(1-Oxo-1,2-dihydro-6-oxa-10b-aza-aceanthrylene-2-ca...)Show InChI InChI=1S/C18H11N3O3S/c22-16(20-18-19-8-9-25-18)14-10-4-3-7-13-15(10)21(17(14)23)11-5-1-2-6-12(11)24-13/h1-9,14H,(H,19,20,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research
Curated by ChEMBL
| Assay Description In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cells |
J Med Chem 33: 2019-24 (1990)
BindingDB Entry DOI: 10.7270/Q2G73F9X |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472603
(CHEMBL65330)Show SMILES CC(C)(C)c1cc(\C=C2/CCN(C(=O)NO)S2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C19H28N2O5S/c1-18(2,3)14-10-12(11-15(16(14)22)19(4,5)6)9-13-7-8-21(17(23)20-24)27(13,25)26/h9-11,22,24H,7-8H2,1-6H3,(H,20,23)/b13-9+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50223539
(CHEMBL33957)Show InChI InChI=1S/C14H15BrO2/c15-12-6-10-7-14(16)17-13(10)8-11(12)9-4-2-1-3-5-9/h6,8-9H,1-5,7H2 | PDB MMDB
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| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In vitro inhibition of prostaglandin synthesis was tested in rat |
J Med Chem 24: 1465-71 (1981)
BindingDB Entry DOI: 10.7270/Q2M61NFB |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472609
(CHEMBL64585)Show SMILES CC(C)(C)c1cc(\C=C2/CCNS2(=O)=O)cc(c1O)C(C)(C)C Show InChI InChI=1S/C18H27NO3S/c1-17(2,3)14-10-12(9-13-7-8-19-23(13,21)22)11-15(16(14)20)18(4,5)6/h9-11,19-20H,7-8H2,1-6H3/b13-9+ | PDB MMDB
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Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50076637
(CHEMBL369252 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...)Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CCN(O)C(C)=O Show InChI InChI=1S/C22H21N3O3/c1-16-6-8-18(9-7-16)22-15-19(5-4-14-24(27)17(2)26)23-25(22)20-10-12-21(28-3)13-11-20/h6-13,15,27H,14H2,1-3H3 | PDB MMDB
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The R.W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibitory activity against 5-lipoxygenase (5-LO) in intact rat barophilic leukemia cells (RBL-1) |
Bioorg Med Chem Lett 9: 979-84 (1999)
BindingDB Entry DOI: 10.7270/Q2Z31XV3 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50076659
(CHEMBL435907 | N-{3-[5-(4-Chloro-phenyl)-1-(4-meth...)Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(Cl)cc1)C#CC(C)N(O)C(C)=O Show InChI InChI=1S/C22H20ClN3O3/c1-15(26(28)16(2)27)4-9-19-14-22(17-5-7-18(23)8-6-17)25(24-19)20-10-12-21(29-3)13-11-20/h5-8,10-15,28H,1-3H3 | PDB MMDB
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The R.W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1) |
Bioorg Med Chem Lett 9: 979-84 (1999)
BindingDB Entry DOI: 10.7270/Q2Z31XV3 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50076650
(CHEMBL368682 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...)Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CC(C)N(O)C(=O)C(C)C Show InChI InChI=1S/C25H27N3O3/c1-17(2)25(29)28(30)19(4)8-11-21-16-24(20-9-6-18(3)7-10-20)27(26-21)22-12-14-23(31-5)15-13-22/h6-7,9-10,12-17,19,30H,1-5H3 | PDB MMDB
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| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
The R.W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibitory activity against 5-lipoxygenase (5-LO) in intact rat barophilic leukemia cells (RBL-1) |
Bioorg Med Chem Lett 9: 979-84 (1999)
BindingDB Entry DOI: 10.7270/Q2Z31XV3 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50279050
(CHEMBL4169347)Show SMILES CS(=O)(=O)c1ccc2n(C(=O)c3ccc(Cl)cc3)c3CCCC(=O)c3c2c1 Show InChI InChI=1S/C20H16ClNO4S/c1-27(25,26)14-9-10-16-15(11-14)19-17(3-2-4-18(19)23)22(16)20(24)12-5-7-13(21)8-6-12/h5-11H,2-4H2,1H3 | PDB MMDB
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| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Damanhour University
Curated by ChEMBL
| Assay Description Binding affinity towards Alpha-1A adrenergic receptor in rat denuded thoracic aorta |
Eur J Med Chem 141: 306-321 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.056 BindingDB Entry DOI: 10.7270/Q2Q242R1 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50223541
(Clofurac)Show InChI InChI=1S/C14H15ClO2/c15-12-6-10-7-14(16)17-13(10)8-11(12)9-4-2-1-3-5-9/h6,8-9H,1-5,7H2 | PDB MMDB
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TBA
Curated by ChEMBL
| Assay Description In vitro inhibition of prostaglandin synthesis was tested in rat |
J Med Chem 24: 1465-71 (1981)
BindingDB Entry DOI: 10.7270/Q2M61NFB |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50076642
(2,2,2-Trifluoro-N-hydroxy-N-{3-[1-(4-methoxy-pheny...)Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CC(C)N(O)C(=O)C(F)(F)F Show InChI InChI=1S/C23H20F3N3O3/c1-15-4-7-17(8-5-15)21-14-18(9-6-16(2)29(31)22(30)23(24,25)26)27-28(21)19-10-12-20(32-3)13-11-19/h4-5,7-8,10-14,16,31H,1-3H3 | PDB MMDB
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| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
The R.W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1) |
Bioorg Med Chem Lett 9: 979-84 (1999)
BindingDB Entry DOI: 10.7270/Q2Z31XV3 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50003117
(3-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-4H-[1,2,4]o...)Show SMILES CC(C)(C)c1cc(cc(c1O)C(C)(C)C)-c1nc(=S)o[nH]1 Show InChI InChI=1S/C16H22N2O2S/c1-15(2,3)10-7-9(13-17-14(21)20-18-13)8-11(12(10)19)16(4,5)6/h7-8,19H,1-6H3,(H,17,18,21) | PDB MMDB
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Warner-Lambert Company
Curated by ChEMBL
| Assay Description Evaluated in vitro for its inhibitory activity against Prostaglandin G/H synthase |
J Med Chem 35: 3691-8 (1992)
BindingDB Entry DOI: 10.7270/Q2M61KWB |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50472604
(CHEBI:35847 | CP-66,248 | Tenidap)Show SMILES NC(=O)N1C(=O)\C(=C(/O)c2cccs2)c2cc(Cl)ccc12 Show InChI InChI=1S/C14H9ClN2O3S/c15-7-3-4-9-8(6-7)11(13(19)17(9)14(16)20)12(18)10-2-1-5-21-10/h1-6,18H,(H2,16,20)/b12-11- | PDB MMDB
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| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd.
Curated by ChEMBL
| Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. |
J Med Chem 43: 2040-8 (2000)
Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50279037
(CHEMBL4173526)Show SMILES CS(=O)(=O)c1ccc2n(Cc3ccc(Cl)cc3)c3CCCCc3c2c1 Show InChI InChI=1S/C20H20ClNO2S/c1-25(23,24)16-10-11-20-18(12-16)17-4-2-3-5-19(17)22(20)13-14-6-8-15(21)9-7-14/h6-12H,2-5,13H2,1H3 | PDB MMDB
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| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Damanhour University
Curated by ChEMBL
| Assay Description Compound was evaluated for its binding affinity against Toxoplasma gondii purine nucleoside phosphorylase of virulent strain RH (value indicates comp... |
Eur J Med Chem 141: 306-321 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.056 BindingDB Entry DOI: 10.7270/Q2Q242R1 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50339185
((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)Show InChI InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1 | PDB MMDB
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| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against Prostaglandin G/H synthase in rat neutrophils |
J Med Chem 29: 1099-113 (1986)
BindingDB Entry DOI: 10.7270/Q2DZ0BHV |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50076639
(CHEMBL367010 | N-{3-[5-(4-Ethyl-phenyl)-1-(4-metho...)Show SMILES CCc1ccc(cc1)-c1cc(nn1-c1ccc(OC)cc1)C#CC(C)N(O)C(C)=O Show InChI InChI=1S/C24H25N3O3/c1-5-19-7-9-20(10-8-19)24-16-21(11-6-17(2)27(29)18(3)28)25-26(24)22-12-14-23(30-4)15-13-22/h7-10,12-17,29H,5H2,1-4H3 | PDB MMDB
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| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
The R.W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1) |
Bioorg Med Chem Lett 9: 979-84 (1999)
BindingDB Entry DOI: 10.7270/Q2Z31XV3 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50076640
(CHEMBL173133 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...)Show SMILES CCC(=O)N(O)CC#Cc1cc(-c2ccc(C)cc2)n(n1)-c1ccc(OC)cc1 Show InChI InChI=1S/C23H23N3O3/c1-4-23(27)25(28)15-5-6-19-16-22(18-9-7-17(2)8-10-18)26(24-19)20-11-13-21(29-3)14-12-20/h7-14,16,28H,4,15H2,1-3H3 | PDB MMDB
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| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
The R.W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibitory activity against cyclooxygenase (COX) in intact rat barophilic leukemia cells (RBL-1) |
Bioorg Med Chem Lett 9: 979-84 (1999)
BindingDB Entry DOI: 10.7270/Q2Z31XV3 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50012867
(1-Oxo-1,2-dihydro-6-thia-10b-aza-aceanthrylene-2-c...)Show InChI InChI=1S/C18H11N3O2S2/c22-16(20-18-19-8-9-24-18)14-10-4-3-7-13-15(10)21(17(14)23)11-5-1-2-6-12(11)25-13/h1-9,14H,(H,19,20,22) | PDB MMDB
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| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research
Curated by ChEMBL
| Assay Description In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cells |
J Med Chem 33: 2019-24 (1990)
BindingDB Entry DOI: 10.7270/Q2G73F9X |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50223525
(CHEMBL35511)Show InChI InChI=1S/C15H17ClO2/c1-9-11-7-13(16)12(8-14(11)18-15(9)17)10-5-3-2-4-6-10/h7-10H,2-6H2,1H3 | PDB MMDB
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| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In vitro inhibition of prostaglandin synthesis was tested in rat |
J Med Chem 24: 1465-71 (1981)
BindingDB Entry DOI: 10.7270/Q2M61NFB |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50279039
(CHEMBL4177185)Show SMILES CS(=O)(=O)c1ccc2n(c3CCCCc3c2c1)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H18ClNO4S2/c1-26(22,23)15-10-11-19-17(12-15)16-4-2-3-5-18(16)21(19)27(24,25)14-8-6-13(20)7-9-14/h6-12H,2-5H2,1H3 | PDB MMDB
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| PC cid PC sid UniChem
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| n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a |
Damanhour University
Curated by ChEMBL
| Assay Description Binding affinity towards Alpha-1A adrenergic receptor in rat denuded thoracic aorta |
Eur J Med Chem 141: 306-321 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.056 BindingDB Entry DOI: 10.7270/Q2Q242R1 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50223540
(CHEMBL34579)Show InChI InChI=1S/C15H11ClO2/c1-9-11-7-13(16)12(8-14(11)18-15(9)17)10-5-3-2-4-6-10/h2-9H,1H3 | PDB MMDB
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| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In vitro inhibition of prostaglandin synthesis was tested in rat |
J Med Chem 24: 1465-71 (1981)
BindingDB Entry DOI: 10.7270/Q2M61NFB |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50223523
(CHEMBL34264)Show InChI InChI=1S/C14H9ClO2/c15-12-6-10-7-14(16)17-13(10)8-11(12)9-4-2-1-3-5-9/h1-6,8H,7H2 | PDB MMDB
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| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In vitro inhibition of prostaglandin synthesis was tested in rat |
J Med Chem 24: 1465-71 (1981)
BindingDB Entry DOI: 10.7270/Q2M61NFB |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50003122
(4-(5-Aminomethyl-[1,2,4]thiadiazol-3-yl)-2,6-di-te...)Show InChI InChI=1S/C17H25N3OS/c1-16(2,3)11-7-10(15-19-13(9-18)22-20-15)8-12(14(11)21)17(4,5)6/h7-8,21H,9,18H2,1-6H3 | PDB MMDB
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| n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Evaluated in vitro for its inhibitory activity against Prostaglandin G/H synthase |
J Med Chem 35: 3691-8 (1992)
BindingDB Entry DOI: 10.7270/Q2M61KWB |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50076650
(CHEMBL368682 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...)Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CC(C)N(O)C(=O)C(C)C Show InChI InChI=1S/C25H27N3O3/c1-17(2)25(29)28(30)19(4)8-11-21-16-24(20-9-6-18(3)7-10-20)27(26-21)22-12-14-23(31-5)15-13-22/h6-7,9-10,12-17,19,30H,1-5H3 | PDB MMDB
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| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
The R.W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibitory activity against 5-lipoxygenase (5-LO) in intact rat barophilic leukemia cells (RBL-1) |
Bioorg Med Chem Lett 9: 979-84 (1999)
BindingDB Entry DOI: 10.7270/Q2Z31XV3 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50279036
(CHEMBL4162061)Show SMILES CS(=O)(=O)c1ccc2n(Cc3ccc(Cl)cc3)c3CCCC(=O)c3c2c1 Show InChI InChI=1S/C20H18ClNO3S/c1-26(24,25)15-9-10-17-16(11-15)20-18(3-2-4-19(20)23)22(17)12-13-5-7-14(21)8-6-13/h5-11H,2-4,12H2,1H3 | PDB MMDB
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| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
Damanhour University
Curated by ChEMBL
| Assay Description Inhibition concentration against human adenosine kinase |
Eur J Med Chem 141: 306-321 (2017)
Article DOI: 10.1016/j.ejmech.2017.09.056 BindingDB Entry DOI: 10.7270/Q2Q242R1 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM22971
(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)Show InChI InChI=1S/C14H11Cl2NO2/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19/h2-7,17H,1H3,(H,18,19) | PDB MMDB
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| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cells |
J Med Chem 36: 1802-10 (1993)
BindingDB Entry DOI: 10.7270/Q2542MPQ |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM17638
(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) | PDB MMDB
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| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Rorer Central Research
Curated by ChEMBL
| Assay Description Invitro inhibition of polymorphonuclear leukocyte derived human 5-lipoxygenase |
J Med Chem 32: 1836-42 (1989)
BindingDB Entry DOI: 10.7270/Q2VT1R21 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM22971
(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)Show InChI InChI=1S/C14H11Cl2NO2/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19/h2-7,17H,1H3,(H,18,19) | PDB MMDB
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TBA
Curated by ChEMBL
| Assay Description Compound was evaluated in an intact RBL-1 cell line for inhibition of 5-Cyclooxygenase |
Bioorg Med Chem Lett 2: 69-72 (1992)
Article DOI: 10.1016/S0960-894X(00)80657-5 BindingDB Entry DOI: 10.7270/Q29K4B4Q |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM22971
(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)Show InChI InChI=1S/C14H11Cl2NO2/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19/h2-7,17H,1H3,(H,18,19) | PDB MMDB
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TBA
Curated by ChEMBL
| Assay Description Binding affinity at 5-hydroxytryptamine 3 receptor in rat posterior cortex by [3H]-BRL 43694 displacement. |
Bioorg Med Chem Lett 2: 705-708 (1992)
Article DOI: 10.1016/S0960-894X(00)80396-0 BindingDB Entry DOI: 10.7270/Q26H4HBV |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM85245
(CAS_36322-90-4 | NSC_4856 | Piroxicam)Show SMILES CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O |t:12| Show InChI InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20) | PDB MMDB
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TBA
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against Prostaglandin G/H synthase in rat neutrophils |
J Med Chem 29: 1099-113 (1986)
BindingDB Entry DOI: 10.7270/Q2DZ0BHV |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1/2
(RAT) | BDBM50224285
(AHR-5850D | Amfenac Sodium | CHEBI:75918)Show InChI InChI=1S/C15H13NO3/c16-14-11(9-13(17)18)7-4-8-12(14)15(19)10-5-2-1-3-6-10/h1-8H,9,16H2,(H,17,18)/p-1 | PDB MMDB
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A.H. Robins Company
Curated by ChEMBL
| Assay Description Inhibitory activity against Prostaglandin G/H synthase |
J Med Chem 33: 2296-304 (1990)
BindingDB Entry DOI: 10.7270/Q2MS3RR7 |
More data for this Ligand-Target Pair | |