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Compile Data Set for Download or QSAR

Found 2 hits of ki for UniProtKB: P12392   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-3/alpha-5/beta-4


(Rattus norvegicus (Rat)-RAT)
BDBM50246823
PNG
(CHEMBL4071277)
Show SMILES OC[C@H]1CNC(=N)N1CCc1cccnc1 |r|
Show InChI InChI=1S/C11H16N4O/c12-11-14-7-10(8-16)15(11)5-3-9-2-1-4-13-6-9/h1-2,4,6,10,16H,3,5,7-8H2,(H2,12,14)/t10-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
957n/an/an/an/an/an/an/an/a



Torrey Pines Institute for Molecular Studies

Curated by ChEMBL


Assay Description
Displacement of [3H]epibatidine from rat alpha3beta4alpha5 nAChR expressed in HEK cells after 2 hrs


J Med Chem 60: 10092-10104 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01250
BindingDB Entry DOI: 10.7270/Q2PG1V5M
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/alpha-5/beta-4


(Rattus norvegicus (Rat)-RAT)
BDBM50246826
PNG
(CHEMBL4084577)
Show SMILES C[C@H]1CNC(=N)N1CCc1cccnc1 |r|
Show InChI InChI=1S/C11H16N4/c1-9-7-14-11(12)15(9)6-4-10-3-2-5-13-8-10/h2-3,5,8-9H,4,6-7H2,1H3,(H2,12,14)/t9-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.62E+3n/an/an/an/an/an/an/an/a



Torrey Pines Institute for Molecular Studies

Curated by ChEMBL


Assay Description
Displacement of [3H]epibatidine from rat alpha3beta4alpha5 nAChR expressed in HEK cells after 2 hrs


J Med Chem 60: 10092-10104 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01250
BindingDB Entry DOI: 10.7270/Q2PG1V5M
More data for this
Ligand-Target Pair