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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Homo sapiens (Human)) | BDBM50519158 (CHEMBL4445812) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet  | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 8.02E+3 | n/a | n/a | n/a | n/a | n/a |
Chengdu University Curated by ChEMBL | Assay Description Binding affinity to wild-type human full length CDK4/cyclinD1 F93L mutant (M1 to E303 residues) expressed in mammalian expression system measured aft... | J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353 BindingDB Entry DOI: 10.7270/Q2X06BF7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Homo sapiens (Human)) | BDBM50519158 (CHEMBL4445812) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 8.02E+3 | n/a | n/a | n/a | n/a | n/a |
Chengdu University Curated by ChEMBL | Assay Description Binding affinity to wild-type human full length CDK4/cyclinD1 (M1 to E303 residues) expressed in mammalian expression system measured after 1 hr by k... | J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353 BindingDB Entry DOI: 10.7270/Q2X06BF7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
