BindingDB PrimarySearch

BDBM50519158 CHEMBL4445812

SMILES: Clc1ccc(cc1Cl)C(=O)Nc1ccc2cc(ccc2c1)C(=O)Nc1nccs1

InChI Key: InChIKey=MRITYVDXXFOOAU-UHFFFAOYSA-N

Data: 44 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 44 hits for monomerid = 50519158
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.11E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to human partial length PIK3CA Q546K mutant (R108 to N1068 residues) expressed in mammalian expression system measured after 1 hr by...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.11E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to human partial length PIK3CA H1047L mutant (R108 to N1068 residues) expressed in mammalian expression system measured after 1 hr b...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK3 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	456	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length PLK3 (A42 to L334 residues) expressed in mammalian expression system measured after 1 hr by kinome...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.02E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human full length CDK9 (M1 to F372 residues) expressed in bacterial expression system measured after 1 hr by kinomescan...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-Dependent Kinase 4 (CDK4) (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.02E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human full length CDK4/cyclinD1 (M1 to E303 residues) expressed in mammalian expression system measured after 1 hr by k...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.11E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length PIK3CD (R108 to Q1044 residues) expressed in mammalian expression system measured after 1 hr by ki...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.11E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length PIK3CG (S144 to A1102 residues) expressed in mammalian expression system measured after 1 hr by ki...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.02E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human full length CDK2 (M1 to L298 residues) expressed in bacterial expression system measured after 1 hr by kinomescan...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.02E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human full length CDK7 (M1 to L344 residues) expressed in mammalian expression system measured after 1 hr by kinomescan...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 8 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.02E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length CDK8 (M1 to T360 residues) expressed in bacterial expression system measured after 1 hr by kinomes...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 19 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.02E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length CDK11 (M1 to N360 residues) expressed in mammalian expression system measured after 1 hr by kinome...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 20 (Homo sapiens)	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.02E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human full-length CDK20 (M1 to G346 residues) expressed in mammalian expression system measured after 1 hr by kinomesca...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 6 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.02E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human full-length CDK6 (M1 to A326 residues) expressed in mammalian expression system measured after 1 hr by kinomescan...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
CDK3/Cyclin E (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.02E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human full length CDK3 (M1 to H305 residues) expressed in bacterial expression system measured after 1 hr by kinomescan...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.02E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human full length CDK4 (M1 to E303 residues) expressed in mammalian expression system measured after 1 hr by kinomescan...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.11E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length PIK3CB (P118 to S1070 residues) expressed in mammalian expression system measured after 1 hr by ki...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.11E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to human partial length PIK3CA M1043I mutant (R108 to N1068 residues) expressed in mammalian expression system measured after 1 hr b...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.11E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to human partial length PIK3CA H1047Y mutant (R108 to N1068 residues) expressed in mammalian expression system measured after 1 hr b...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.11E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to human partial length PIK3CA E545K mutant (R108 to N1068 residues) expressed in mammalian expression system measured after 1 hr by...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.11E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to human partial length PIK3CA E542K mutant (R108 to N1068 residues) expressed in mammalian expression system measured after 1 hr by...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.11E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to human partial length PIK3CA C420R mutant (R108 to N1068 residues) expressed in mammalian expression system measured after 1 hr by...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.11E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length PIK3CA (R108 to N1068 residues) expressed in mammalian expression system measured after 1 hr by ki...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 4 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.32E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length ERK4 (M1 to L365 residues) expressed in bacterial expression system measured after 1 hr by kinomes...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 6 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.32E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length ERK3 (M1 to P413 residues) expressed in bacterial expression system measured after 1 hr by kinomes...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
MAP kinase ERK1 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.32E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human full length ERK1 Q122L mutant (M1 to P379 residues) expressed in bacterial expression system measured after 1 hr ...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
MAP kinase ERK1 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.32E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human full length ERK1 (M1 to P379 residues) expressed in bacterial expression system measured after 1 hr by kinomescan...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	272	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length PLK2 (H58 to F354 residues) expressed in mammalian expression system measured after 1 hr by kinome...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length AURKB (D25 to A303 residues) expressed in mammalian expression system measured after 1 hr by Kinom...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.32E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human full length ERK2 (M1 to S360 residues) expressed in bacterial expression system measured after 1 hr by kinomescan...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Aurora-C (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	289	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human full length AURKC (M1 to S275 residues) expressed in bacterial expression system measured after 1 hr by Kinomesca...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-Dependent Kinase 4 (CDK4) (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.02E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human full length CDK4/cyclinD1 F93L mutant (M1 to E303 residues) expressed in mammalian expression system measured aft...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent-like kinase 5 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.02E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human full length CDK5 (M1 to P292 residues) expressed in bacterial expression system measured after 1 hr by kinomescan...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 10 (Homo sapiens)	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.02E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human full-length CDK10 (M1 to P360 residues) expressed in mammalian expression system measured after 1 hr by kinomesca...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.11E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to human partial length PIK3CA I800L mutant (R108 to N1068 residues) expressed in mammalian expression system measured after 1 hr by...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.11E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to human partial length PIK3CA E545A mutant (R108 to N1068 residues) expressed in mammalian expression system measured after 1 hr by...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 15 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.32E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length ERK8 (M1 to P437 residues) expressed in bacterial expression system measured after 1 hr by kinomes...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
CDK4/Cyclin D3 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.02E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human full length CDK4/cyclinD3 (M1 to E303 residues) expressed in mammalian expression system measured after 1 hr by k...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular signal-regulated kinase 5 (ERK5) (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.32E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length ERK5 (M1 to A409 residues) expressed in bacterial expression system measured after 1 hr by kinomes...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length PLK1 (A33 to F325 residues) expressed in mammalian expression system measured after 1 hr by kinome...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.02E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human full-length CDK1 (M1 to M297 residues) expressed in mammalian expression system measured after 1 hr by kinomescan...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.11E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length PIK3C2B (M1 to L1634 residues) expressed in mammalian expression system measured after 1 hr by kin...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length AURKA (E122 to K401 residues) expressed in mammalian expression system measured after 1 hr by Kino...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 12 (Homo sapiens)	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.02E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length CDK12 (P697 to E1077 residues) expressed in mammalian expression system measured after 1 hr by kin...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50519158 (CHEMBL4445812) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.11E+3	n/a	n/a	n/a	n/a	n/a
Chengdu University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length PIK3C2G (M1 to I1446 residues) expressed in mammalian expression system measured after 1 hr by kin...				J Med Chem 62: 7697-7707 (2019) Article DOI: 10.1021/acs.jmedchem.9b00353
Chengdu University Curated by ChEMBL					More data for this Ligand-Target Pair