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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 7' and Ligand = 'BDBM50519158'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 7


(Homo sapiens (Human))		BDBM50519158
PNG
(CHEMBL4445812)
Show SMILES Clc1ccc(cc1Cl)C(=O)Nc1ccc2cc(ccc2c1)C(=O)Nc1nccs1
Show InChI InChI=1S/C21H13Cl2N3O2S/c22-17-6-4-15(11-18(17)23)19(27)25-16-5-3-12-9-14(2-1-13(12)10-16)20(28)26-21-24-7-8-29-21/h1-11H,(H,25,27)(H,24,26,28)
PDB
MMDB

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KEGG

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MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 8.02E+3n/an/an/an/an/a



Chengdu University

Curated by ChEMBL


Assay Description
Binding affinity to wild-type human full length CDK7 (M1 to L344 residues) expressed in mammalian expression system measured after 1 hr by kinomescan...

J Med Chem 62: 7697-7707 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00353
BindingDB Entry DOI: 10.7270/Q2X06BF7
More data for this
Ligand-Target Pair