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Compile Data Set for Download or QSAR

Found 4 hits of ec50 for monomerid = 55084   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM55084
PNG
(N-[4-[(2-chlorobenzoyl)amino]-3-fluoro-phenyl]pico...)
Show SMILES Fc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1ccccc1Cl
Show InChI InChI=1S/C19H13ClFN3O2/c20-14-6-2-1-5-13(14)18(25)24-16-9-8-12(11-15(16)21)23-19(26)17-7-3-4-10-22-17/h1-11H,(H,23,26)(H,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 480n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2VT1QHF
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM55084
PNG
(N-[4-[(2-chlorobenzoyl)amino]-3-fluoro-phenyl]pico...)
Show SMILES Fc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1ccccc1Cl
Show InChI InChI=1S/C19H13ClFN3O2/c20-14-6-2-1-5-13(14)18(25)24-16-9-8-12(11-15(16)21)23-19(26)17-7-3-4-10-22-17/h1-11H,(H,23,26)(H,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 556n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization


J Med Chem 54: 1106-10 (2011)


Article DOI: 10.1021/jm101271s
BindingDB Entry DOI: 10.7270/Q27P90C1
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Rattus norvegicus (Rat))
BDBM55084
PNG
(N-[4-[(2-chlorobenzoyl)amino]-3-fluoro-phenyl]pico...)
Show SMILES Fc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1ccccc1Cl
Show InChI InChI=1S/C19H13ClFN3O2/c20-14-6-2-1-5-13(14)18(25)24-16-9-8-12(11-15(16)21)23-19(26)17-7-3-4-10-22-17/h1-11H,(H,23,26)(H,24,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 739n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization


J Med Chem 54: 1106-10 (2011)


Article DOI: 10.1021/jm101271s
BindingDB Entry DOI: 10.7270/Q27P90C1
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 [Q124R]


(Rattus norvegicus)
BDBM55084
PNG
(N-[4-[(2-chlorobenzoyl)amino]-3-fluoro-phenyl]pico...)
Show SMILES Fc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1ccccc1Cl
Show InChI InChI=1S/C19H13ClFN3O2/c20-14-6-2-1-5-13(14)18(25)24-16-9-8-12(11-15(16)21)23-19(26)17-7-3-4-10-22-17/h1-11H,(H,23,26)(H,24,25)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/an/an/a 740n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2DR2SWV
More data for this
Ligand-Target Pair