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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 1304   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)
BDBM1304
PNG
(3-Aminopyridin-2(1H)-one analogue 24 | 5-ethyl-3-[...)
Show SMILES CCc1cc(NCc2ccco2)c(=O)[nH]c1C
Show InChI InChI=1S/C13H16N2O2/c1-3-10-7-12(13(16)15-9(10)2)14-8-11-5-4-6-17-11/h4-7,14H,3,8H2,1-2H3,(H,15,16)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.88E+4n/an/an/an/an/an/a



Organon Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of HIV-1 reverse transcriptase (HIV-1 RT)


J Med Chem 39: 4065-72 (1996)


Article DOI: 10.1021/jm960058h
BindingDB Entry DOI: 10.7270/Q2Z039F0
More data for this
Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147]


(Human immunodeficiency virus type 1)
BDBM1304
PNG
(3-Aminopyridin-2(1H)-one analogue 24 | 5-ethyl-3-[...)
Show SMILES CCc1cc(NCc2ccco2)c(=O)[nH]c1C
Show InChI InChI=1S/C13H16N2O2/c1-3-10-7-12(13(16)15-9(10)2)14-8-11-5-4-6-17-11/h4-7,14H,3,8H2,1-2H3,(H,15,16)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.90E+4n/an/an/an/a8.2n/a



Merck Research Laboratories



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.


J Med Chem 35: 3792-802 (1992)


Article DOI: 10.1021/jm00099a007
BindingDB Entry DOI: 10.7270/Q2GH9G3P
More data for this
Ligand-Target Pair